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In comparison with persons who never used analgesics, increased relative risks (RR) were seen for users of phenacetin\u2010containing drugs after adjustment for smoking and high\u2010risk occupational exposure (men: RR = 2.4; women: RR = 4.2). A significant relative risk for aspirin use among women was also observed. There was an indication of a dose\u2010effect relationship for both types of analgesics. The influence of phenacetin and aspirin on the development of renal pelvis and ureter tumours could not be separated since in this study the two compounds occurred so frequently in the same formulation. Experimental studies and phenacetin metabolism makes it biologically most relevant to attribute the observed association in the present study to the phenacetin component of the drugs.<\/jats:p>","DOI":"10.1002\/ijc.2910440603","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T21:51:19Z","timestamp":1171921879000},"page":"965-968","source":"Crossref","is-referenced-by-count":34,"title":["The copenhagen case\u2010control study of renal pelvis and ureter cancer: Role of analgesics"],"prefix":"10.1002","volume":"44","author":[{"given":"O. M.","family":"Jensen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. B.","family":"Knudsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Tomasson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B. 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