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Among the cases, 18 (60%) were non\u2010smokers and 14 (47%) non\u2010drinkers, the corresponding proportions in the controls being 52% and 44%. Thus, there was no apparent relation between tobacco, alcohol and the risk of adenocarcinoma of the oesophagus, the age\u2010 and sex\u2010adjusted point estimates being 1.0 for moderate and 0.9 for heavy smokers, 0.7 and 1.5 respectively for moderate and heavy drinkers. Upper 95% confidence limits were 1.6 for ever\u2010use of tobacco and 1.9 for ever alcohol drinking. The findings of this study, although based on a limited number of cases, indicate that alcohol and tobacco are unlikely to play a major role in the aetiology of adenocarcinoma in Barrett's oesophagus.<\/jats:p>","DOI":"10.1002\/ijc.2910450511","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T21:55:30Z","timestamp":1171922130000},"page":"852-854","source":"Crossref","is-referenced-by-count":52,"title":["The consumption of tobacco, alcohol and the risk of adenocarcinoma in Barrett's oesophagus"],"prefix":"10.1002","volume":"45","author":[{"given":"Fabio","family":"Levi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean\u2010Baptiste","family":"Olloy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlo","family":"La Vecchia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Boyle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philippe","family":"Monnier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcel","family":"Savary","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,17]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.18003815005"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198510033131404"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.294.6570.461"},{"key":"e_1_2_1_5_1","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/S0016-5085(84)80016-5","article-title":"Clinical, epidemiologic, and morphologic comparison between adenocarcinomas arising in Barrett's esophageal mucosa and in the gastric cardia","volume":"86","author":"Kalish R. 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