{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T18:18:22Z","timestamp":1790878702180,"version":"4.1.0"},"reference-count":44,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2006,7,17]],"date-time":"2006-07-17T00:00:00Z","timestamp":1153094400000},"content-version":"vor","delay-in-days":5487,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[1991,7,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The roles of ethnic origin, pigmentray traits, sun sensitivity and other cutaneous characteristics as risk factors for basal\u2010cell carcinoma (BCC) and squamous\u2010cell carcinoma (SCC) were examnied in a case\u2010control study of prevalent and incident cases of histopathologically confirmed skin cancers. Two hundred and twenty six confirmed cases of BCC, 45 of SCC and 1,015 controls with no lesions were identified in a population\u2010based survey of skin cancer in 1987 in Geralditon, Western Australia. The risk of both cancers was higher in nativeborn Australians than in migrants. The risk of BCC decreased with increasing age at arrival in Australia. Southern European ancestry was strongly protective against BCC (for any southern European grandparents) and SCC (no case of SCC had any granparetns of southern European origin). Inability to tan was the strongest pigmentary risk factor for both BCC and SCC. Among Factors that incorporated a measure of sun exposure as well as sun sensitivity, freckling on the arm in childhood was important for both cancers, the number of moles on the back was important for BCC, and forearm skin colour and having a permanent colour difference between the neck and adjacent protected areas were important for SCC. Among measures of sun damage to the skin, solar elastosis of the neck was a strong risk factor for both BCC and SCC, loss of fine texture of the sink of the back of the hands (as measured by cutaneous microtopography) was important for BCC and telangiectasia of the face for SCC. When all important variables for each cancer were examined together in a single model with age, sex, migrant status or age at arrival in Australia, and ethnicity, inability to tan, solar elastosis of the neck, and the number of moles on the back were independently significant risk factors for BCC and solar elatosis of the neck and having a permanent colour difference between the neck and adjacent protected areas were independently sifnificant risk factors for SCC. The effects of age at arrival or migrant status and ethnic origin remeained important on the models incorporating these factors. A history of ever having acne and a history of warts were protective for BCC and a history of acne was protective for SCC.<\/jats:p>","DOI":"10.1002\/ijc.2910480504","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T22:22:45Z","timestamp":1171923765000},"page":"650-662","source":"Crossref","is-referenced-by-count":180,"title":["Pigmentary and cutaneous risk factors for non\u2010melanocytic skin cancer\u2014A case\u2010control study"],"prefix":"10.1002","volume":"48","author":[{"given":"Anne","family":"Kricker","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce K.","family":"Armstrong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dallas R.","family":"English","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter J.","family":"Heenan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,7,17]]},"reference":[{"key":"e_1_2_1_2_1","volume-title":"Mortality from cancer in migrants to Australia\u20141962\u20131971","author":"Armstrong B. 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