{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T03:55:25Z","timestamp":1790913325608,"version":"4.1.0"},"reference-count":38,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2006,7,18]],"date-time":"2006-07-18T00:00:00Z","timestamp":1153180800000},"content-version":"vor","delay-in-days":5363,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[1991,11,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    In order to evaluate the protective role of the maternal antibody against mother\u2010to\u2010child transmission of HTLV\u2010I, we followed a total of 780 children born to HTLV\u2010I carrier mothers by investigating the level of anti\u2010HTLV\u2010l antibody transferred\n                    <jats:italic>in utero<\/jats:italic>\n                    , decline of the maternal antibody and seroconversion in post\u2010natal life. The anti\u2010HTLV\u20101 antibody was positively detected within the first 3\u20106 months of life and declined at 6\u201012 months after birth in all children. After the maternal antibody declined, seroconversion occurred in some of the children following either breast feeding or bottle feeding. The seroconversion rates of short\u2010term (\u22666 months) and long\u2010term (\u22677 months) breast feeders were 4.4% (4\/90 cases) and 14.4% (20\/139 cases), and the rate of bottle feeders was 5.7% (9\/158 cases). Long\u2010term breast feeding yielded more seroconverters than short\u2010term breast feeding; 14.4% (20\/139 cases) vs. 4.4% (4\/90 cases), RR = 3.68, p = 0.018. The seroconversion rate of short\u2010term breast feeders was nearly equal to that of bottle feeders; 4.4% (4\/90 cases) vs. 5.7% (9\/158 cases), RR = 0.770, p = 0.471. When neonatal lymphocytes were cultured with breast milk cells of HTLV\u2010I carrier mothers, the\n                    <jats:italic>in vitro<\/jats:italic>\n                    infection of HTLV\u2010I was inhibited by the addition of HTLV\u2010I\u2010seropositive cord\u2010blood plasma. Our results suggest that the maternal antibody may inhibit HTLV\u2010I infection by short\u2010term breast feeding but not by long\u2010term breast feeding after decline of the maternal antibody.\n                  <\/jats:p>","DOI":"10.1002\/ijc.2910490508","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T17:47:04Z","timestamp":1171907224000},"page":"673-677","source":"Crossref","is-referenced-by-count":121,"title":["Inhibitory effect of maternal antibody on mother\u2010to\u2010child transmission of human T\u2010lymphotropic virus type I"],"prefix":"10.1002","volume":"49","author":[{"given":"Kazuo","family":"Takahashi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiro","family":"Takezaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshitaka","family":"Oki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyoshi","family":"Kawakami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinji","family":"Yashiki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshinobu","family":"Fujiyoshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kouichiro","family":"Usuku","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"THE MOTHER\u2010TO\u2010CHILD TRANSMISSION STUDY GROUP","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy","family":"Mueller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuhiro","family":"Osame","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kouichiro","family":"Miyata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukihiro","family":"Nagata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunro","family":"Sonoda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,7,18]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(77)81021-4"},{"key":"e_1_2_1_3_1","first-page":"322","article-title":"Transmission of adult T\u2010cell leukemia retrovirus (HTLV\u2010I) from mother to child: comparison of bottle\u2010fed with breast\u2010fed babies","volume":"78","author":"Ando Y.","year":"1987","journal-title":"Jap. 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