{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T15:54:31Z","timestamp":1765727671279},"reference-count":39,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,7,18]],"date-time":"2006-07-18T00:00:00Z","timestamp":1153180800000},"content-version":"vor","delay-in-days":5164,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[1992,5,28]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Lymphocytes adhere to cells or extracellular matrices to perform functions relating to cytotoxicity, extravasation and tissue localization, as well as modulation of lymphocyte growth and maturation. This adherence is mainly mediated by 3 families of cell\u2010surface adhesion molecules: integrins, immunoglobulin\u2010related molecules and selectins. Since variations in the degree of adherence may affect the pathophysiology of lymphoproliferative disorders, the expression of a large number of adhesion molecules was analysed on Epstein\u2010Barr virus (EBV)\u2010transformed lymphoblastoid cell lines (LCLs), and on EBV\u2010positive or EBV\u2010negative Burkitt's lymphoma (BL) lines, by immunofluorescence flow cytometry and immunoprecipitation with monoclonal antibodies. With regard to the \u03b21, \u03b22 and \u03b23 integrin subfamilies, LCLs strongly expressed CD49d\/CD29 (VLA\u20104), CDIIa\/CD18 (Leu\u2010CAMa, LFA\u20101) and CD5I\/CD6I (vitronectin receptor). These cells also abundantly expressed CD54 (ICAM\u2010I) and CD58 (LFA\u20103) as well as the \u201ehoming receptors\u201d\ufe01 L\u2010selectin (LECAM\u2010I) and CD44, BL lines had considerably lower amounts of VLA\u20104 than LCLs, and ICAM\u20101 was expressed only by some of the tumor lines. All other adhesion molecules were absent or minimally expressed in the BL cells.<\/jats:p>","DOI":"10.1002\/ijc.2910510319","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T22:56:40Z","timestamp":1171925800000},"page":"452-458","source":"Crossref","is-referenced-by-count":32,"title":["Expression of integrins and other adhesion molecules in epstein\u2010barr virus\u2010transformed B lymphoblastoid cells and Burkitt's lymphoma cells"],"prefix":"10.1002","volume":"51","author":[{"given":"Jorge","family":"Rincon","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacqueline","family":"Prieto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Patarroyo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,18]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910470412"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910400521"},{"key":"e_1_2_1_4_1","first-page":"1","article-title":"Cellular and molecular mechanisms that direct leukocyte traffic","volume":"136","author":"Butcher E. C.","year":"1990","journal-title":"Amer. J. Pathol."},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(87)92924-2"},{"key":"e_1_2_1_6_1","doi-asserted-by":"crossref","first-page":"4082","DOI":"10.4049\/jimmunol.144.11.4082","article-title":"Role of ICAM\u2010I in antigen presentation demonstrated by ICAM\u20101 defective mutants","volume":"144","author":"Dang L. H.","year":"1990","journal-title":"J. Immunol."},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1697696"},{"key":"e_1_2_1_8_1","first-page":"3361","article-title":"Human B lymphocytes define an alternative mechanism of adhesion to fibronectin","volume":"144","author":"Garcia\u2010Pardo A.","year":"1990","journal-title":"J. Immunol."},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.167.6.1811"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-71-7-1481"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.139.1.313"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.iy.08.040190.002053"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1989.tb03566.x"},{"key":"e_1_2_1_14_1","first-page":"383","article-title":"Expression of a human homing receptor (CD44) in lymphoid malignancies and related stages of lymphoid development","volume":"4","author":"Horst E.","year":"1990","journal-title":"Leukemia"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.2237417"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.134.5.3003"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(89)90394-2"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.173.6.1297"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-230X(08)60470-4"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830200326"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.173.2.343"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/0090-1229(87)90132-2"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/0046-8177(89)90075-0"},{"key":"e_1_2_1_24_1","first-page":"320","article-title":"Phenotypic and cytogenetic characteristics of human B\u2010lymphoid cell lines and their relevance for the etiology of Burkitt's lymphoma","volume":"37","author":"Nilsson K.","year":"1982","journal-title":"Advanc. Cancer Res."},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910380414"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(87)81321-2"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3083.1989.tb01197.x"},{"key":"e_1_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910410623"},{"key":"e_1_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.1990.tb00562.x"},{"key":"e_1_2_1_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/0090-1229(91)90091-N"},{"key":"e_1_2_1_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1990.tb08275.x"},{"key":"e_1_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI114957"},{"key":"e_1_2_1_33_1","first-page":"517","volume-title":"Leukocyte typing","author":"Schmidt R. E.","year":"1989"},{"key":"e_1_2_1_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/346425a0"},{"key":"e_1_2_1_35_1","doi-asserted-by":"crossref","first-page":"532","DOI":"10.4049\/jimmunol.144.2.532","article-title":"Expression of the human leukocyte adhesion molecule, LAM1. Identity with the TQ1 and Leu\u20108 differentiation antigens","volume":"144","author":"Tedder T. F.","year":"1990","journal-title":"J. Immunol."},{"key":"e_1_2_1_36_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.83.15.5620"},{"key":"e_1_2_1_37_1","doi-asserted-by":"crossref","first-page":"1827","DOI":"10.1182\/blood.V75.9.1827.1827","article-title":"Low expression of lymphocyte function associated antigen (LFA)\u20101 and LFA\u20103 adhesion molecules is a common trait in Burkitt's lymphoma associated with and not associated with Epstein\u2010Barr virus","volume":"75","author":"Villaud M.","year":"1990","journal-title":"Blood"},{"key":"e_1_2_1_38_1","first-page":"951","volume-title":"Leukocyte typing","author":"von Dem Borne A.","year":"1989"},{"key":"e_1_2_1_39_1","series-title":"IARC Scientific Publication 60","first-page":"37","volume-title":"Burkitt's lymphoma: a human cancer model","author":"Wright D. H.","year":"1985"},{"key":"e_1_2_1_40_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V77.10.2231.2231"}],"container-title":["International Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fijc.2910510319","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.2910510319","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,24]],"date-time":"2023-10-24T02:47:42Z","timestamp":1698115662000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ijc.2910510319"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,5,28]]},"references-count":39,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1992,5,28]]}},"alternative-id":["10.1002\/ijc.2910510319"],"URL":"https:\/\/doi.org\/10.1002\/ijc.2910510319","archive":["Portico"],"relation":{},"ISSN":["0020-7136","1097-0215"],"issn-type":[{"value":"0020-7136","type":"print"},{"value":"1097-0215","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,5,28]]}}}