{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T18:25:34Z","timestamp":1750962334283},"reference-count":28,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2009,10,13]],"date-time":"2009-10-13T00:00:00Z","timestamp":1255392000000},"content-version":"vor","delay-in-days":6039,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[1993,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In order to investigate etiologic distinctions among the anatomic sub\u2010sites of the large bowel by sex, the relationship between large\u2010bowel\u2010cancer incidence and age at diagnosis, time period at diagnosis, and birth cohort was analyzed by anatomic sub\u2010site and by sex, using data from the Connecticut Tumor Registry. Included in the study were all incident large\u2010bowel\u2010cancer cases occurring between 1950 and 1984 among Connecticut residents aged 40 to 79. Cancers of the large bowel were classified into 5 anatomic sub\u2010sites: Ascending colon (including cecum), transverse colon (including flexures), descending colon, sigmoid colon, and rectum (including rectosigmoid junction, anal canal, and anus). The data were fitted to log\u2010linear age\u2010period\u2010cohort models. For each of the sub\u2010sites, the age\u2010period\u2010cohort patterns for males and females differed. Within each sex, sub\u2010site groupings with common patterns were indicated. Among males, the age\u2010period\u2010cohort patterns for the colon sub\u2010sites were fairly similar; but the pattern for the rectum differed markedly from that for the colon sub\u2010sites. There were secondary differences among the colon sub\u2010sites that pointed to a secondary distinction between the right and the left colons. Among females, the age\u2010period\u2010cohort patterns for the left colon sub\u2010sites and the rectum were fairly similar. The pattern for the transverse colon differed moderately from that of the left colon, and differed substantially from that of the rectum and the ascending colon. The ascending colon differed markedly from each of the other sub\u2010sites. It is possible that these differences in age\u2010period\u2010cohort patterns reflect etiologic distinctions among sub\u2010site groupings and between the sexes.<\/jats:p>","DOI":"10.1002\/ijc.2910530607","type":"journal-article","created":{"date-parts":[[2010,7,7]],"date-time":"2010-07-07T18:14:53Z","timestamp":1278526493000},"page":"907-913","source":"Crossref","is-referenced-by-count":21,"title":["Age\u2010period\u2010cohort modelling of large\u2010bowel\u2010cancer incidence by anatomic sub\u2010site and sex in connecticut"],"prefix":"10.1002","volume":"53","author":[{"given":"Robert","family":"Dubrow","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonine","family":"Bernstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theodore R.","family":"Holford","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,10,13]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1954.1"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(196606)19:6<750::AID-CNCR2820190603>3.0.CO;2-B"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02553382"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-113-10-779"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-230X(08)60086-X"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910100305"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/jech.43.4.356"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.3109\/02841869009096379"},{"key":"e_1_2_1_10_1","first-page":"571","volume-title":"Analysis of qualitative data","author":"Haberman S. J.","year":"1979"},{"key":"e_1_2_1_11_1","volume-title":"Forty\u2010five years of cancer incidence in Connecticut: 1935\u201379","author":"Heston J. F.","year":"1986"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.2307\/2531004"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.pu.12.050191.002233"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1984.262"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a115165"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910470314"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/030089169107700313"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02564165"},{"key":"e_1_2_1_19_1","first-page":"1201","article-title":"Reproduction, endogenous and exogenous sex hormones, and colon cancer: A review and hypothesis","volume":"65","author":"McMichael A. J.","year":"1980","journal-title":"J. Nat. Cancer Inst."},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a113672"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.2930440109"},{"key":"e_1_2_1_22_1","volume-title":"Cancer risk and incidence trends\u2014the Connecticut perspective","author":"Roush G. C.","year":"1987"},{"key":"e_1_2_1_23_1","first-page":"216","article-title":"Changing distribution of carcinoma of the colon and rectum","volume":"158","author":"Slater G. I.","year":"1984","journal-title":"Surg. Gyn. Obs."},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01694509"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19841215)54:12<3065::AID-CNCR2820541242>3.0.CO;2-C"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19901201)66:11<2442::AID-CNCR2820661134>3.0.CO;2-5"},{"key":"e_1_2_1_27_1","first-page":"197","volume-title":"Important advances in oncology, 1987","author":"Weisburger J. H.","year":"1987"},{"key":"e_1_2_1_28_1","volume-title":"ICD\u2010O, international classification of diseases for oncology","author":"World Health Organization","year":"1976"},{"key":"e_1_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1987.140"}],"container-title":["International Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fijc.2910530607","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.2910530607","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,26]],"date-time":"2023-10-26T02:10:20Z","timestamp":1698286220000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ijc.2910530607"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,4]]},"references-count":28,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1993,4]]}},"alternative-id":["10.1002\/ijc.2910530607"],"URL":"https:\/\/doi.org\/10.1002\/ijc.2910530607","archive":["Portico"],"relation":{},"ISSN":["0020-7136","1097-0215"],"issn-type":[{"value":"0020-7136","type":"print"},{"value":"1097-0215","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,4]]}}}