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The CD24 antigen, a glyco\u2010sylphosphatidylinositol\u2010anchored cell surface molecule, has been identified as a B\u2010cell marker that is lost during cell maturation. We show here that it is expressed on 3 NPC xenografts, previously defined as consisting of poorly differentiated epithelial cells, and on an NPC biopsy. In the case of the former, the level of expression of CD24 corresponds to the EBV load. A B\u2010lymphoblastoid cell line carrying the same EBV genome as one of the tumours, C15, and an EBV\u2010negative Burkitt's lymphoma cell line do not display the antigen, but epithelial\u2010like cells of a laryngeal tumour cell line (Hep2) do express it. Our data suggest that CD24 may be a marker of cell differentiation not only for B cells but also for epithelial cells and may have an indirect association with EBV gene expression.<\/jats:p>","DOI":"10.1002\/ijc.2910600422","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T00:41:49Z","timestamp":1171932109000},"page":"562-566","source":"Crossref","is-referenced-by-count":26,"title":["Expression of a B\u2010cell marker, CD24, on nasopharyngeal carcinoma cells"],"prefix":"10.1002","volume":"60","author":[{"given":"Lorainc","family":"Karran","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Jones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gary","family":"Morley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"Van Noorden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irvin","family":"Lampert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beverly E.","family":"Griffin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,18]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.84.17.6262"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910420422"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.66.5.3257-3262.1992"},{"key":"e_1_2_1_5_1","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1128\/jvi.64.3.1002-1013.1990","article-title":"Stable transfection of Epstein\u2010Barr virus (EBV) nuclear antigen 2 in lymphoma cells containing the EBV P3HRI genome induces expression of B cell activation molecules GD2I and CD23","volume":"64","author":"Cordier M.","year":"1990","journal-title":"J. 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