{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T08:09:51Z","timestamp":1780387791443,"version":"3.54.1"},"reference-count":23,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2006,7,17]],"date-time":"2006-07-17T00:00:00Z","timestamp":1153094400000},"content-version":"vor","delay-in-days":3897,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[1995,11,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Thd investigate the genetic background of human T\u2010cell leukemia virus type I (HTLV\u2010I) and II (HTLV\u2010IIhd carriers among South American native Indians, we analyzed HLA DRBI*\u2010DQBI * haplotypes of the virus carriers from Andes highlands and Orinoco lowlands by the PCR\u2010RFLP genotyping method. It was revealed that the HTLV\u2010I\u2010carrying Andes natives had one of the 5 HLA haplotypes: DRBI*\u2010DQBI* 0403\u20100302, 0802\u20100402, 0901\u20100303, 1406\u20100302 and 0407\u20100302, and that the Orinoco HTLV\u2010II carriers had one of the 3 HLA haplotypes: DRBI*\u2010DQBI* 1402\u20100301, 1602\u20100301 and 0404\u20100302. The HLA haplotypes of Andes HTLV\u2010I carriers and Orinoco HTLV\u2010II carriers were mutually exclusive. The haplotypes associated with HTLV\u2010I carriers were commonly found among the Andes Indians and Japanese, which is the known HTLV\u2010I endemic population, while the haplotypes associated with HTLV\u2010II carriers were specifically found among the Orinoco Indians and North American Indians, among whom HTLV\u2010II is endemic. These reults suggested that HLA haplotypes might be ethnically segregated among South American natives and might be involved in the susceptibility to HTLV\u2010I and HTLV\u2010II infections.<\/jats:p>","DOI":"10.1002\/ijc.2910630409","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T01:11:41Z","timestamp":1171933901000},"page":"510-515","source":"Crossref","is-referenced-by-count":13,"title":["Ethnic segregation of HTLV\u2010I and HTLV\u2010II carriers among South American native Indians"],"prefix":"10.1002","volume":"63","author":[{"given":"Toshinobu","family":"Fujiyoshi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinji","family":"Yashiki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chihaya","family":"Fujiyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Kuwayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Miyashita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Ohnishi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Blank","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladimir","family":"Zaninovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abraham","family":"Blank","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Cartier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John J.","family":"Byrnes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"William J.","family":"Harrington","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoyuki","family":"Miura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masanori","family":"Hayami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuo","family":"Tajima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunro","family":"Sonoda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,7,17]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0039.1995.tb02426.x"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4613-0705-1_21"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/scientificamerican1191-104"},{"key":"e_1_2_1_5_1","first-page":"185","volume-title":"Human retrovirology","author":"Cleghorn F.","year":"1990"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/168.4.1075"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/359201a0"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1006\/smvy.1994.1017"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V76.3.450.450"},{"key":"e_1_2_1_10_1","first-page":"23","article-title":"Peopling of the Americas, founded by four major lineages of mitochondrial DNA","volume":"10","author":"Horai S.","year":"1993","journal-title":"Mol. Biol. Evol"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1349-7006.1995.tb02983.x"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-5728(93)90004-I"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/166.1.100"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0039.1991.tb01881.x"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0039.1992.tb01935.x"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1990.43.410"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.80.12.3618"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.82.10.3101"},{"key":"e_1_2_1_19_1","first-page":"129","volume-title":"Advances in adult T\u2010cell leukemia and HTL V\u2010l research. Gann Monograph on Cancer Research No. 39","author":"Tajima K.","year":"1992"},{"key":"e_1_2_1_20_1","volume-title":"HLA 1991","author":"Tsuji K.","year":"1992"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/317395a0"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/162.3.649"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1349-7006.1990.tb02633.x"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1089\/aid.1994.10.97"}],"container-title":["International Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fijc.2910630409","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.2910630409","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,26]],"date-time":"2023-10-26T02:48:48Z","timestamp":1698288528000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ijc.2910630409"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,11,15]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1995,11,15]]}},"alternative-id":["10.1002\/ijc.2910630409"],"URL":"https:\/\/doi.org\/10.1002\/ijc.2910630409","archive":["Portico"],"relation":{},"ISSN":["0020-7136","1097-0215"],"issn-type":[{"value":"0020-7136","type":"print"},{"value":"1097-0215","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,11,15]]}}}