{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T18:27:26Z","timestamp":1788200846625,"version":"build-2803163510"},"reference-count":23,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2014,12,1]],"date-time":"2014-12-01T00:00:00Z","timestamp":1417392000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U19AI08408"],"award-info":[{"award-number":["U19AI08408"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U54CA164336"],"award-info":[{"award-number":["U54CA164336"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2015,6,15]]},"abstract":"<jats:p>In the United States, high\u2010risk human papillomavirus (HPV) testing is recommended for women with atypical squamous cells of unknown significance (ASC\u2010US) cytology, and co\u2010testing with cytology and HPV is a recommended option for screening women aged \u226530 years. No population\u2010based data are available to examine utilization of HPV testing in the United States. Using the New Mexico HPV Pap Registry data resource, we describe population trends (2007\u20132012) in utilization and positivity rates for HPV testing as a routine co\u2010testing screening procedure and for triage of ASC\u2010US and other cytologic outcomes. For women aged 30\u201365 years co\u2010testing increased from 5.2% in 2007 to 19.1% in 2012 (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Overall 82% of women with ASC\u2010US cytology who did not receive co\u2010testing also had an HPV test. HPV positivity was age and cytology result dependent but did not show time trends. For women with negative cytology, 64% received an additional screening test within 3 years if no co\u2010test was done or if it was positive, but this was reduced to 47% with a negative co\u2010test. Reflex HPV testing for ASC\u2010US cytology is well established and occurs in most women. Evidence for reflex testing is also observed following other abnormal cytology outcomes. Co\u2010testing in women aged 30\u201365 years has more than tripled from 2007 to 2012, but was still only used in 19.1% of women aged 30\u201365 years attending for screening in 2012. Women receiving co\u2010testing had longer repeat screening intervals, but rescreening within 3 years is still very common even with co\u2010testing.<\/jats:p>","DOI":"10.1002\/ijc.29337","type":"journal-article","created":{"date-parts":[[2014,11,19]],"date-time":"2014-11-19T14:14:32Z","timestamp":1416406472000},"page":"2854-2863","source":"Crossref","is-referenced-by-count":30,"title":["Human papillomavirus testing 2007\u20132012: <scp>C<\/scp>o\u2010testing and triage utilization and impact on subsequent clinical management"],"prefix":"10.1002","volume":"136","author":[{"given":"Jack","family":"Cuzick","sequence":"first","affiliation":[{"name":"Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine Queen Mary University of London London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orrin","family":"Myers","sequence":"additional","affiliation":[{"name":"Division of Epidemiology, Biostatistics and Preventive Medicine University of New Mexico Health Sciences Center Albuquerque NM"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William C.","family":"Hunt","sequence":"additional","affiliation":[{"name":"House of Prevention Epidemiology (HOPE), Department of Pathology University of New Mexico Health Sciences Center Albuquerque NM"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debbie","family":"Saslow","sequence":"additional","affiliation":[{"name":"Cancer Control Science Department American Cancer Society Atlanta GA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip E.","family":"Castle","sequence":"additional","affiliation":[{"name":"Global Cancer Initiative Chestertown MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walter","family":"Kinney","sequence":"additional","affiliation":[{"name":"Division of Gynecologic Oncology Kaiser Permanente Medical Care Program Oakland CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan","family":"Waxman","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology University of New Mexico Health Science Center School of Medicine Albuquerque NM"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Robertson","sequence":"additional","affiliation":[{"name":"House of Prevention Epidemiology (HOPE), Department of Pathology University of New Mexico Health Sciences Center Albuquerque NM"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cosette M.","family":"Wheeler","sequence":"additional","affiliation":[{"name":"House of Prevention Epidemiology (HOPE), Department of Pathology University of New Mexico Health Sciences Center Albuquerque NM"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the New Mexico HPV Pap Registry Steering Committee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,12]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-13-0973"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.287.16.2120"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.3322\/canjclin.52.6.342"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(03)00745-2"},{"key":"e_1_2_7_6_1","first-page":"1759","article-title":"Screening for cervical cancer: recommendations and rationale","volume":"67","author":"Anonymous","year":"2003","journal-title":"Am Fam Physician"},{"key":"e_1_2_7_7_1","unstructured":"FDA. 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