{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T13:23:03Z","timestamp":1762521783558,"version":"3.37.3"},"reference-count":31,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2015,4,15]],"date-time":"2015-04-15T00:00:00Z","timestamp":1429056000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Instituto Nacional del Cancer and Ministry of Health"},{"DOI":"10.13039\/501100003074","name":"Agencia Nacional de Promoci\u00f3n Cient\u00edfica y Tecnol\u00f3gica","doi-asserted-by":"crossref","award":["PICT 2012-747"],"award-info":[{"award-number":["PICT 2012-747"]}],"id":[{"id":"10.13039\/501100003074","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:p>The aim of this article is to present results of programmatic introduction of HPV testing with cytologic triage among women 30 years and older in the province of Jujuy, Argentina, including description of the planning phase and results of program performance during the first year. We describe the project implementation process, and calculate key performance indicators using SITAM, the national screening information system. We also compare disease detection rates of HPV testing in 2012 with cytology as performed during the previous year. HPV testing with cytology triage was introduced through a consensus\u2010building process. Key activities included establishment of algorithms and guidelines, creating the HPV laboratory, training of health professionals, information campaigns for women and designing the referral network. By the end of 2012, 100% (<jats:italic>n<\/jats:italic>\u2009=\u2009270) of public health care centers were offering HPV testing and 22,834 women had been HPV tested, 98.5% (<jats:italic>n<\/jats:italic>\u2009=\u200922,515) were 30+. HPV positivity among women over 30 was 12.7%, 807 women were HPV+ and had abnormal cytology, and 281 CIN2+ were identified. CIN2+ detection rates was 1.25 in 2012 and 0.62 in 2011 when the program was cytology based (<jats:italic>p<\/jats:italic>\u2009=\u20090.0002). This project showed that effective introduction of HPV testing in programmatic contexts of low\u2010middle income settings is feasible and detects more disease than cytology.<\/jats:p>","DOI":"10.1002\/ijc.29530","type":"journal-article","created":{"date-parts":[[2015,3,25]],"date-time":"2015-03-25T01:46:48Z","timestamp":1427248008000},"page":"1709-1718","source":"Crossref","is-referenced-by-count":38,"title":["Implementation of <scp>HPV<\/scp>\u2010testing for cervical cancer screening in programmatic contexts: The <scp>J<\/scp>ujuy demonstration project in <scp>A<\/scp>rgentina"],"prefix":"10.1002","volume":"137","author":[{"given":"Silvina","family":"Arrossi","sequence":"first","affiliation":[{"name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas\/Centro de Estudios de Estado y Sociedad, S\u00e1nchez de Bustamante 27 Buenos Aires Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Thouyaret","sequence":"additional","affiliation":[{"name":"Programa Nacional de Prevenci\u00f3n de C\u00e1ncer Cervicouterino\/Instituto Nacional del C\u00e1ncer (Argentina) Julio A. Roca 781 Piso 9 Buenos Aires Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosa","family":"Laudi","sequence":"additional","affiliation":[{"name":"Programa Nacional de Prevenci\u00f3n de C\u00e1ncer Cervicouterino\/Instituto Nacional del C\u00e1ncer Rivadavia 875 Buenos Aires Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oscar","family":"Mar\u00edn","sequence":"additional","affiliation":[{"name":"Hospital Pablo Soria G\u00fcemes 1345 San Salvador de Jujuy Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josefina","family":"Ram\u00edrez","sequence":"additional","affiliation":[{"name":"Ministerio de Salud de la provincia de Jujuy, Av. Italia Esq, Independencia San Salvador de Jujuy Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melisa","family":"Paolino","sequence":"additional","affiliation":[{"name":"Programa Nacional de Prevenci\u00f3n de C\u00e1ncer Cervicouterino\/Instituto Nacional del C\u00e1ncer (Argentina) Julio A. Roca 781 Piso 9 Buenos Aires Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rolando","family":"Herrero","sequence":"additional","affiliation":[{"name":"International Agency for Research on Cancer 150 Cours Albert Thomas Lyon France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alicia","family":"Campanera","sequence":"additional","affiliation":[{"name":"Ministerio de Salud de la Provincia de Jujuy, Av. Italia Esq, Independencia San de Salvador de Jujuy Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,4,15]]},"reference":[{"volume-title":"GLOBOCAN 2012 v1.0, cancer incidence and mortality worldwide: IARC CancerBase No. 11 [Internet]","year":"2013","author":"Ferlay J","key":"e_1_2_7_2_1"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0188-0128(99)00006-8"},{"key":"e_1_2_7_4_1","first-page":"954","article-title":"Effective screening programmes for cervical cancer in low\u2010 and middle\u2010income developing countries","volume":"79","author":"Sankaranarayanan R","year":"2001","journal-title":"Bull World Health Organ"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1020-49892010001000003"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2006.05.061"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2008.06.019"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0808516"},{"key":"e_1_2_7_9_1","first-page":"330","volume-title":"Stewart BW, Wild CP, eds. Word cancer report","author":"Von Karsa L","year":"2014"},{"key":"e_1_2_7_10_1","first-page":"156","volume-title":"Atlas de tendencias de mortalidad por c\u00e1ncer. Argentina, 1980\u20102001","author":"Loria D","year":"2007"},{"volume-title":"Datos epidemiol\u00f3gicos [Internet; in Spanish]","year":"2014","author":"Programa Nacional de Prevenci\u00f3n de C\u00e1ncer Cervicouterino","key":"e_1_2_7_11_1"},{"volume-title":"Resoluci\u00f3n 1472\/11 \u201cProyecto Demostraci\u00f3n para la incorporaci\u00f3n de la Prueba de HPV como Tamizaje Primario\u201d [in Spanish]","year":"2011","author":"Bolet\u00edn Oficial de la Rep\u00fablica Argentina","key":"e_1_2_7_12_1"},{"key":"e_1_2_7_13_1","first-page":"44","article-title":"Vacuna contra el virus del papiloma humano: resultados a un a\u00f1o de su incorporaci\u00f3n al calendario nacional de vacunaci\u00f3n","volume":"4","author":"Katz N","year":"2013","journal-title":"Revista Argentina de Salud P\u00fablica"},{"volume-title":"Informe final: Diagn\u00f3stico de situaci\u00f3n del Programa Nacional y Programas Provinciales","year":"2008","author":"Arrossi S","key":"e_1_2_7_14_1"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1851-82652012000400003"},{"key":"e_1_2_7_16_1","unstructured":"LaudiR.La centralizaci\u00f3n de los laboratorios de citolog\u00eda en programas organizados de prevenci\u00f3n de c\u00e1ncer cervicouterino [dissertation; in Spanish]. San Javier Argentina: V Seminario Internacional \u201cProgramas de Tamizajes basados en el Test de VPH: herramientas para su efectiva implementaci\u00f3n\u201d;2013. [update 2014 March 23; cited 2015 February 27]. Available from:http:\/\/www.msal.gov.ar\/cancer-cervico-uterino\/images\/stories\/4-seminarios\/pdf\/Seminario2013\/dia1\/mesa4\/2014-04_rosa-laudi_centralizacion-lab.pdf."},{"volume-title":"Censo Nacional de Poblaci\u00f3n y Viviendas 2010 [Internet; in Spanish]","year":"2014","author":"INDEC","key":"e_1_2_7_17_1"},{"volume-title":"Cervical cancer screening information system","year":"2014","author":"World Health Organization","key":"e_1_2_7_18_1"},{"key":"e_1_2_7_19_1","unstructured":"ArrossiS.Introducci\u00f3n del Test de VPH en Argentina. Principales lecciones para transferir al resto del pa\u00eds [dissertation]. Buenos Aires Argentina: IV Seminario Internacional \u201cPrevenci\u00f3n del C\u00e1ncer Cervicouterino en Argentina en la era del VPH: lo nuevo lo recorrido lo que vendr\u00e1\u201d;2012. [update 2014 March 23; cited 2014 November 5]. Available from:http:\/\/www.msal.gov.ar\/cancer-cervico-uterino\/images\/stories\/4-seminarios\/pdf\/Seminario2012\/dia1\/bloque2\/2014-04_4_Arrossi-Introduccion-Test-VPH-Argentinanueva.pdf\/Spanish."},{"volume-title":"Recomendaciones para el tamizaje, seguimiento y tratamiento de mujeres para la prevenci\u00f3n del c\u00e1ncer cervico\u2010uterino en el marco de la incorporaci\u00f3n de la prueba de VPH [in Spanish]","year":"2011","author":"Ministerio de Salud de la Naci\u00f3n","key":"e_1_2_7_20_1"},{"key":"e_1_2_7_21_1","unstructured":"Mar\u00ednO.Experiencia de integraci\u00f3n laboratorial de la citolog\u00eda\u2010histolog\u00eda\u2010test de HPV: La experiencia Juje\u00f1a [dissertation; in Spanish]. San Javier Argentina: V Seminario Internacional \u201cProgramas de Tamizajes basados en el Test de VPH: herramientas para su efectiva implementaci\u00f3n\u201d;2013. [update 2014 March 23; cited 2014 November 5]. Available from:http:\/\/www.msal.gov.ar\/cancer-cervico-uterino\/images\/stories\/4-seminarios\/pdf\/Seminario2013\/dia1\/mesa4\/2014-04_oscar-marin_experiencia-integracin-lab-cit-hist-jujuy.pdf."},{"volume-title":"Material Gr\u00e1fico \u00c1rea de Prevenci\u00f3n de C\u00e1ncer Cervicouterino [Internet; in Spanish]","year":"2012","author":"Instituto Nacional del C\u00e1ncer","key":"e_1_2_7_22_1"},{"key":"e_1_2_7_23_1","unstructured":"CampaneraA. Seguimiento y tratamiento de mujeres con lesiones precancerosas en el PPCCU\u2010Jujuy 2013 [dissertation; in Spanish]. San Javier Argentina: V Seminario Internacional \u201cProgramas de Tamizajes basados en el Test de VPH: herramientas para su efectiva implementaci\u00f3n\u201d;2013. [update 2014 March 23; cited 2014 November 5]. Available from:http:\/\/www.msal.gov.ar\/cancer-cervico-uterino\/images\/stories\/4-seminarios\/pdf\/Seminario2013\/dia2\/mesa2\/2014-04_6__aliciacampanera_seg-trata-experienciajujuy.pdf\/."},{"volume-title":"Resoluci\u00f3n Ministerial 7665\/11 [in Spanish]","year":"2011","author":"Bolet\u00edn Oficial e Imprenta del Estado de la Provincia de Jujuy","key":"e_1_2_7_24_1"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0968-8080(08)32410-0"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0036-36342008000400005"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(09)70360-2"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/"},{"key":"e_1_2_7_29_1","first-page":"60","volume-title":"WHO guidelines for screening and treatment of precancerous lesions for cervical cancer prevention","author":"World Health Organization","year":"2013"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2012.06.095"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)62218-7"},{"key":"e_1_2_7_32_1","unstructured":"LaudiR.A cuatro a\u00f1os del relanzamiento del Programa Nacional de Prevenci\u00f3n de C\u00e1ncer Cervicouterino (PNPCC): Balance de trabajo [dissertation; in Spanish]. Buenos Aires Argentina: IV Seminario Internacional \u201cPrevenci\u00f3n del C\u00e1ncer Cervicouterino en Argentina en la era del VPH: lo nuevo lo recorrido lo que vendr\u00e1\u201d;2012. [update 2014 March 23; cited 2014 November 5]. Available from:http:\/\/www.msal.gov.ar\/cancer-cervico-uterino\/images\/stories\/4-seminarios\/pdf\/Seminario2012\/dia1\/bloque1\/2014-04_3_laudi-rosa_a-cuatro-anois-del-relanzamiento-programa-nacional.pdf\/."}],"container-title":["International Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fijc.29530","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fijc.29530","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.29530","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T16:47:31Z","timestamp":1695574051000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ijc.29530"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,15]]},"references-count":31,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2015,10]]}},"alternative-id":["10.1002\/ijc.29530"],"URL":"https:\/\/doi.org\/10.1002\/ijc.29530","archive":["Portico"],"relation":{},"ISSN":["0020-7136","1097-0215"],"issn-type":[{"type":"print","value":"0020-7136"},{"type":"electronic","value":"1097-0215"}],"subject":[],"published":{"date-parts":[[2015,4,15]]}}}