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The aim of this study was to evaluate whether gender and ethnic differences in incidence and survival of LN subtypes existed using the Singapore Cancer Registry (SCR) from 1998 to 2012. We derived age standardised incidence rates (ASIRs) by the direct standardisation method and 5\u2010year relative survival (RSR) by the Ederer II method and period approach. Five\u2010year observed survival (OS) was obtained for each ethnicity. Malays had the highest ASIR of total LNs among the three ethnicities for each time period. The largest increase in 5\u2010year RSR subtypes was follicular lymphoma from 43.8% in 1998\u20132002 to 82.3% in 2008\u20132012; followed by chronic lymphocytic leukaemia (CLL)\/small lymphocytic lymphoma (SLL) from 48.1% in 1998\u20132002 to 77.9% in 2008\u20132012. Although males had higher incidence than females in each time period, females had greater 5\u2010year RSR for follicular lymphoma (89.8% in 2008\u20132012 for females<jats:italic>vs<\/jats:italic>. 76.6% in 2008\u20132012 for males) and CLL\/SLL (78.7% in 2008\u20132012 for females<jats:italic>vs<\/jats:italic>. 76.7% in 2008\u20132012 for males). All three ethnicities experienced an overall increase in 5\u2010year OS for mature B\u2010cell lymphoma, with Indians experiencing the greatest increase (37.1% in 1998\u20132002 to 61.1% in 2008\u20132012), followed by Malays (30.8% in 1998\u20132002 to 48.7% in 2008\u20132012) and then Chinese (36.4% in 1998\u20132002 to 51.3% in 2008\u20132012). Our study demonstrated that improved mature B\u2010cell lymphoma survival was not only observed in the West, but also in Singapore.<\/jats:p>","DOI":"10.1002\/ijc.29635","type":"journal-article","created":{"date-parts":[[2015,6,10]],"date-time":"2015-06-10T13:54:30Z","timestamp":1433944470000},"page":"2674-2687","source":"Crossref","is-referenced-by-count":32,"title":["Gender and ethnic differences in incidence and survival of lymphoid neoplasm subtypes in an<scp>A<\/scp>sian population: Secular trends of a population\u2010based cancer registry from 1998 to 2012"],"prefix":"10.1002","volume":"137","author":[{"given":"Raymond Boon Tar","family":"Lim","sequence":"first","affiliation":[{"name":"National Registry of Diseases Office, Health Promotion Board Singapore"},{"name":"Saw Swee Hock School of Public Health National University of Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"En Yun","family":"Loy","sequence":"additional","affiliation":[{"name":"National Registry of Diseases Office, Health Promotion Board Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gek Hsiang","family":"Lim","sequence":"additional","affiliation":[{"name":"National Registry of Diseases Office, Health Promotion Board Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huili","family":"Zheng","sequence":"additional","affiliation":[{"name":"National Registry of Diseases Office, Health Promotion Board Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khuan Yew","family":"Chow","sequence":"additional","affiliation":[{"name":"National Registry of Diseases Office, Health Promotion Board Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soon Thye","family":"Lim","sequence":"additional","affiliation":[{"name":"National Cancer Centre Singapore, SingHealth Singapore"},{"name":"Duke\u2010National University of Singapore Graduate Medical School Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,6,25]]},"reference":[{"key":"e_1_2_8_2_1","volume-title":"Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 11 [Internet]","author":"Ferlay J","year":"2013"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-004-0939-7"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hyp106"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-06-2508"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clml.2011.07.002"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.21824"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2003.10.007"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1309\/AJCP7YLTQPUSDQ5C"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/1746-1596-6-77"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1827.2007.02207.x"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.5045\/kjh.2012.47.1.28"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(14)70282-7"},{"key":"e_1_2_8_14_1","doi-asserted-by":"crossref","first-page":"547\u20102.","DOI":"10.1155\/2009\/547582","article-title":"Outpatient\u2010based therapy of oral fludarabine and subcutaneous alemtuzumab for Asian patients with relapsed\/refractory chronic lymphocytic leukemia","volume":"2009","author":"Hwang WY","year":"2009","journal-title":"Adv Hematol"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/10428190701809156"},{"key":"e_1_2_8_16_1","volume-title":"National Registry of Diseases Office. 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