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Based on cancer incidence for the period 1950\u20131995 in a cohort of 27,011 Chinese medical diagnostic X\u2010ray workers and a comparison cohort of 25,782 Chinese physicians who did not use X\u2010ray equipment in their work, we used Poisson regression to fit excess relative risk (ERR) and excess absolute risk (EAR) dose\u2013response models for incidence of all solid cancers combined. Radiation dose reconstruction was based on a previously published method that relied on simulating measurements for multiple X\u2010ray machines, workplaces and working conditions, information about protective measures, including use of lead aprons, and work histories. The resulting model was used to estimate calendar year\u2010specific badge dose calibrated as personal dose equivalent (Sv). To obtain calendar year\u2010specific colon doses (Gy), we applied a standard organ conversion factor. A total of 1,643 cases of solid cancer were identified in 1.45 million person\u2010years of follow\u2010up. In both ERR and EAR models, a statistically significant radiation dose\u2013response relationship was observed for solid cancers as a group. Averaged over both sexes, and using colon dose as the dose metric, the estimated ERR\/Gy was 0.87 (95% CI: 0.48, 1.45), and the EAR was 22 per 10<jats:sup>4<\/jats:sup>PY\u2010Gy (95% CI: 14, 32) at age 50. We obtained estimates of the ERR and EAR of solid cancers per unit dose that are compatible with those derived from other populations chronically exposed to low dose\u2010rate occupational or environmental radiation.<\/jats:p>","DOI":"10.1002\/ijc.30036","type":"journal-article","created":{"date-parts":[[2016,2,10]],"date-time":"2016-02-10T10:39:43Z","timestamp":1455100783000},"page":"2875-2883","source":"Crossref","is-referenced-by-count":46,"title":["Solid cancer incidence among <scp>C<\/scp>hinese medical diagnostic x\u2010ray workers, 1950\u20131995: Estimation of radiation\u2010related risks"],"prefix":"10.1002","volume":"138","author":[{"given":"Zhijuan","family":"Sun","sequence":"first","affiliation":[{"name":"Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine Institute of Radiation Medicine, Chinese Academy of Medical Sciences &amp; Peking Union Medical College Tianjin China"},{"name":"Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics National Cancer Institute, National Institutes of Health Bethesda MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter D.","family":"Inskip","sequence":"additional","affiliation":[{"name":"Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics National Cancer Institute, National Institutes of Health Bethesda MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jixian","family":"Wang","sequence":"additional","affiliation":[{"name":"Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine Institute of Radiation Medicine, Chinese Academy of Medical Sciences &amp; Peking Union Medical College Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deukwoo","family":"Kwon","sequence":"additional","affiliation":[{"name":"Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics National Cancer Institute, National Institutes of Health Bethesda MD"},{"name":"University of Miami School of Medicine Silvestre Comprehensive Cancer Center Miami FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongcheng","family":"Zhao","sequence":"additional","affiliation":[{"name":"Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine Institute of Radiation Medicine, Chinese Academy of Medical Sciences &amp; Peking Union Medical College Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liangan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine Institute of Radiation Medicine, Chinese Academy of Medical Sciences &amp; Peking Union Medical College Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qin","family":"Wang","sequence":"additional","affiliation":[{"name":"Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine Institute of Radiation Medicine, Chinese Academy of Medical Sciences &amp; Peking Union Medical College Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saijun","family":"Fan","sequence":"additional","affiliation":[{"name":"Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine Institute of Radiation Medicine, Chinese Academy of Medical Sciences &amp; Peking Union Medical College Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,3,25]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"UNSCEAR (United Nations Scientific Committee on the Effects of Atomic Radiation). 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