{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T06:54:30Z","timestamp":1776754470259,"version":"3.51.2"},"reference-count":47,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,5,14]],"date-time":"2016-05-14T00:00:00Z","timestamp":1463184000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["KL2 TR000421"],"award-info":[{"award-number":["KL2 TR000421"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:p>Higher body mass index (BMI) is a well\u2010established risk factor for colorectal cancer (CRC), but is inconsistently associated with CRC survival. In 6 prospective studies participating in the Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO), 2,249 non\u2010Hispanic white CRC cases were followed for a median 4.5 years after diagnosis, during which 777 died, 554 from CRC\u2010related causes. Associations between prediagnosis BMI and survival (overall and CRC\u2010specific) were evaluated using Cox regression models adjusted for age at diagnosis, sex, study and smoking status (current\/former\/never). The association between BMI category and CRC survival varied by cancer stage at diagnosis (I\u2010IV) for both all\u2010cause (<jats:italic>p\u2010<\/jats:italic>interaction\u2009=\u20090.03) and CRC\u2010specific mortality (<jats:italic>p\u2010<\/jats:italic>interaction\u2009=\u20090.04). Compared to normal BMI (18.5\u201324.9 kg\/m<jats:sup>2<\/jats:sup>), overweight (BMI 25.0\u201329.9) was associated with increased mortality among those with Stage I disease, and decreased mortality among those with Stages II\u2013IV disease. Similarly, obesity (BMI \u226530) was associated with increased mortality among those with Stages I\u2013II disease, and decreased mortality among those with Stages III\u2013IV disease. These results suggest the relationship between BMI and survival after CRC diagnosis differs by stage at diagnosis, and may emphasize the importance of adequate metabolic reserves for colorectal cancer survival in patients with late\u2010stage disease.<\/jats:p>","DOI":"10.1002\/ijc.30163","type":"journal-article","created":{"date-parts":[[2016,4,28]],"date-time":"2016-04-28T09:38:56Z","timestamp":1461836336000},"page":"1065-1072","source":"Crossref","is-referenced-by-count":34,"title":["Relationship of prediagnostic body mass index with survival after colorectal cancer: Stage\u2010specific associations"],"prefix":"10.1002","volume":"139","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8084-1608","authenticated-orcid":false,"given":"Jonathan M.","family":"Kocarnik","sequence":"first","affiliation":[{"name":"Department of Epidemiology University of Washington Seattle WA"},{"name":"Division of Public Health Sciences Fred Hutchinson Cancer Research Center Seattle WA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew T.","family":"Chan","sequence":"additional","affiliation":[{"name":"Channing Laboratory, Department of Medicine, Brigham and Women's Hospital Boston MA"},{"name":"Division of Gastroenterology Massachusetts General Hospital Boston MA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martha L.","family":"Slattery","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine University of Utah Health Sciences Center Salt Lake City UT"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John D.","family":"Potter","sequence":"additional","affiliation":[{"name":"Division of Public Health Sciences Fred Hutchinson Cancer Research Center Seattle WA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey","family":"Meyerhardt","sequence":"additional","affiliation":[{"name":"Dana\u2010Farber Cancer Institute Boston MA"},{"name":"Brigham and Women's Hospital Boston MA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda","family":"Phipps","sequence":"additional","affiliation":[{"name":"Department of Epidemiology University of Washington Seattle WA"},{"name":"Division of Public Health Sciences Fred Hutchinson Cancer Research Center Seattle WA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongmei","family":"Nan","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Richard M. Fairbanks School of Public Health Indiana University Indianapolis IN"},{"name":"Indiana University Melvin and Bren Simon Cancer Center Indianapolis IN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tabitha","family":"Harrison","sequence":"additional","affiliation":[{"name":"Division of Public Health Sciences Fred Hutchinson Cancer Research Center Seattle WA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas E.","family":"Rohan","sequence":"additional","affiliation":[{"name":"Department of Epidemiology &amp; Population Health Albert Einstein College of Medicine Bronx NY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lihong","family":"Qi","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences, School of Medicine University of California Davis Davis CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lifang","family":"Hou","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine and the Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine Northwestern University Chicago IL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bette","family":"Caan","sequence":"additional","affiliation":[{"name":"Division of Research Kaiser Permanente Northern California Oakland CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Candyce H.","family":"Kroenke","sequence":"additional","affiliation":[{"name":"Division of Research Kaiser Permanente Northern California Oakland CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Howard","family":"Strickler","sequence":"additional","affiliation":[{"name":"Department of Epidemiology &amp; Population Health Albert Einstein College of Medicine Bronx NY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard B.","family":"Hayes","sequence":"additional","affiliation":[{"name":"Division of Epidemiology New York University School of Medicine New York NY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert E.","family":"Schoen","sequence":"additional","affiliation":[{"name":"Department of Medicine and Epidemiology University of Pittsburgh Medical Center Pittsburgh PA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dawn Q.","family":"Chong","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology Massachusetts General Hospital Boston MA"},{"name":"Division of Medical Oncology National Cancer Centre Singapore  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily","family":"White","sequence":"additional","affiliation":[{"name":"Department of Epidemiology University of Washington Seattle WA"},{"name":"Division of Public Health Sciences Fred Hutchinson Cancer Research Center Seattle WA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonja I.","family":"Berndt","sequence":"additional","affiliation":[{"name":"Division of Cancer Epidemiology &amp; Genetics National Cancer Institute Bethesda MD"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrike","family":"Peters","sequence":"additional","affiliation":[{"name":"Department of Epidemiology University of Washington Seattle WA"},{"name":"Division of Public Health Sciences Fred Hutchinson Cancer Research Center Seattle WA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Polly A.","family":"Newcomb","sequence":"additional","affiliation":[{"name":"Department of Epidemiology University of Washington Seattle WA"},{"name":"Division of Public Health Sciences Fred Hutchinson Cancer Research Center Seattle WA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,5,14]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"FerlayJ SI ErvikM DikshitR et al. GLOBOCAN 2012 v1.0 Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 11 [Internet] Lyon France: International Agency for Research on Cancer; 2013. Available at:http:\/\/globocan.iarc.fr. (Accessed on February 24 2016)."},{"key":"e_1_2_7_3_1","unstructured":"HowladerN NA KrapchoM GarshellJ et al. (eds). SEER Cancer Statistics Review 1975\u20102012 National Cancer Institute. Bethesda MD http:\/\/seer.cancer.gov\/csr\/1975_2012\/ based on November 2014 SEER data submission posted to the SEER web site April2015."},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21235"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2013-304701"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/13813450801954303"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/obr.12140"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.38.0287"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-012-0071-2"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-11-0079"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(01)01802-2"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ypmed.2014.02.003"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2012.12.020"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001648-199011000-00009"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.2307\/3462013"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198801283180431"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0197-2456(00)00098-2"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0197-2456(00)00097-0"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwh010"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1047-2797(03)00042-5"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0197-2456(97)00078-0"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2012.04.052"},{"key":"e_1_2_7_23_1","first-page":"1","article-title":"Physical status: the use and interpretation of anthropometry. Report of a WHO Expert Committee","volume":"854","year":"1995","journal-title":"World Health Organ Tech Rep Ser"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwu121"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.158.17.1855"},{"key":"e_1_2_7_26_1","unstructured":"StataCorp. Stata Statistical Software: Release 14 College Station TX: StataCorp LP 2015."},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-005-0360-0"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-10-0522"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.28573"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-015-0664-7"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.28841"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1242\/dmm.009613"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39367.495995.AE"},{"key":"e_1_2_7_34_1","volume-title":"Food, Nutrition, Physical Activity, and the Prevention of Cancer: a Global Perspective","author":"World Cancer Research Fund\/American Institute for Cancer Research","year":"2007"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa055643"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2012.113905"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1010679"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60318-4"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2009.0056"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2009.0058"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.113.071399"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwu111"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2008.87"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-012-2436-x"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-09-2636"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2015.1796"},{"key":"e_1_2_7_47_1","doi-asserted-by":"crossref","DOI":"10.1093\/jnci\/djv198","article-title":"Patterns of Colorectal Cancer Care in the United States: 1990\u20102010","volume":"107","author":"Murphy CC","year":"2015","journal-title":"J Natl Cancer Inst"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2014.09.038"}],"container-title":["International Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fijc.30163","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fijc.30163","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.30163","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T16:23:15Z","timestamp":1695572595000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ijc.30163"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5,14]]},"references-count":47,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["10.1002\/ijc.30163"],"URL":"https:\/\/doi.org\/10.1002\/ijc.30163","archive":["Portico"],"relation":{},"ISSN":["0020-7136","1097-0215"],"issn-type":[{"value":"0020-7136","type":"print"},{"value":"1097-0215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,5,14]]}}}