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We searched the Medline database for relevant studies published by January 2016. We extracted information on the study design and the positive predictive value (PPV) of self\u2010reported FHC, defined as the proportion of reported cancer diagnoses among relatives that was confirmed by a reference standard (as a measure of over\u2010reporting). We also extracted information on sensitivity of self\u2010reported FHC (as a measure of underreporting). Overall, 21 studies were included that provided information on the PPV of self\u2010reported FHC for relevant cancers and four studies also provided information on sensitivity. The PPV was highest (mostly &gt;70%) for pancreatic, lung, thyroid and urinary system cancers and for leukemia and lymphoma, while it was lowest for stomach and liver cancer. Sensitivity was highest (&gt;70%) for pancreatic cancer, lung cancer, brain cancer, melanoma, leukemia and lymphoma. For several cancers, sample sizes were low and the number of studies limited, particularly regarding sensitivity of self\u2010reported FHC. In conclusion, for some cancers (<jats:italic>e.g<\/jats:italic>., pancreatic cancer, lung cancer, leukemia, lymphoma) self\u2010reported FHC can be considered sufficiently valid to be useful, for example, in preventive counseling. For several cancers, it is not sufficiently studied or the pattern is inconsistent. This needs to be taken into account when using self\u2010reported information about FHC in clinical practice or epidemiological research.<\/jats:p>","DOI":"10.1002\/ijc.30203","type":"journal-article","created":{"date-parts":[[2016,5,25]],"date-time":"2016-05-25T03:11:35Z","timestamp":1464145895000},"page":"1449-1460","source":"Crossref","is-referenced-by-count":51,"title":["Validity of self\u2010reported family history of cancer: A systematic literature review on selected cancers"],"prefix":"10.1002","volume":"139","author":[{"given":"Jonas","family":"Fiederling","sequence":"first","affiliation":[{"name":"Epidemiological Cancer Registry Baden\u2010Wuerttemberg, German Cancer Research Center (DKFZ) Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad Zia","family":"Shams","sequence":"additional","affiliation":[{"name":"Epidemiological Cancer Registry Baden\u2010Wuerttemberg, German Cancer Research Center (DKFZ) Heidelberg 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