{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T19:25:55Z","timestamp":1792092355737,"version":"4.4.0"},"reference-count":31,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2016,8,16]],"date-time":"2016-08-16T00:00:00Z","timestamp":1471305600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2016,8,16]],"date-time":"2016-08-16T00:00:00Z","timestamp":1471305600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","award":["2014\u20102271"],"award-info":[{"award-number":["2014\u20102271"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2016,12,1]]},"abstract":"<jats:p>\n                    Literature focusing on health\u2010related quality of life (HRQoL) by cancer site among women only is scarce. This study examines HRQoL of breast cancer (BC) survivors compared with female survivors of other cancers, and to understand which subgroups of BC survivors were particularly at risk of reduced HRQoL. We placed emphasis on young (&lt;50 years) and recently diagnosed (\u22645 years) survivors, where the deficits in HRQoL were most pronounced. The cross\u2010sectional study consisted of 2,224 BC survivors, 8,504 non\u2010cancer controls and 2,205 other cancer survivors in the Karma study. We examined HRQoL differences using linear regression analyses in the whole cohort and in a subset of young and recently diagnosed BC survivors (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u2009242) and female survivors of other cancers (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u2009140) with comparable ages at diagnosis (43.6 vs 43.6,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.917) and time since diagnosis (2.3 vs 2.8 years,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001). HRQoL was assessed using the EORTC QLQ\u2010C30 questionnaire. While only cognitive functioning was significantly compromised in BC survivors compared with survivors of other cancers when women of all ages were included, young BC survivors reported significantly lower HRQoL on multiple functional scales (global quality of life, emotional, role, social and cognitive functioning) and experienced more fatigue and insomnia. BC survivors with any prior medical history of mental disorders reported poorer HRQoL than those without such a history. We also observed a close\u2013knit relationship between tumor and treatment characteristics. BC survivors perform poorly in HRQoL in comparison with female survivors of other cancers. Our results emphasize the importance of age\u2010 and gender\u2010appropriate comparison groups.\n                  <\/jats:p>","DOI":"10.1002\/ijc.30370","type":"journal-article","created":{"date-parts":[[2016,8,3]],"date-time":"2016-08-03T11:38:12Z","timestamp":1470224292000},"page":"2415-2425","source":"Crossref","is-referenced-by-count":28,"title":["Worse quality of life in young and recently diagnosed breast cancer survivors compared with female survivors of other cancers: A cross\u2010sectional study"],"prefix":"10.1002","volume":"139","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8587-7511","authenticated-orcid":false,"given":"Jingmei","family":"Li","sequence":"first","affiliation":[{"name":"Department of Medical Epidemiology and Biostatistics Karolinska Institutet Stockholm 171 77 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith","family":"Humphreys","sequence":"additional","affiliation":[{"name":"Department of Medical Epidemiology and Biostatistics Karolinska Institutet Stockholm 171 77 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikael","family":"Eriksson","sequence":"additional","affiliation":[{"name":"Department of Medical Epidemiology and Biostatistics Karolinska Institutet Stockholm 171 77 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huma","family":"Dar","sequence":"additional","affiliation":[{"name":"Department of Medical Epidemiology and Biostatistics Karolinska Institutet Stockholm 171 77 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yvonne","family":"Brandberg","sequence":"additional","affiliation":[{"name":"Department of Oncology and Pathology Karolinska Institutet Stockholm 171 77 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per","family":"Hall","sequence":"additional","affiliation":[{"name":"Department of Medical Epidemiology and Biostatistics Karolinska Institutet Stockholm 171 77 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamila","family":"Czene","sequence":"additional","affiliation":[{"name":"Department of Medical Epidemiology and Biostatistics Karolinska Institutet Stockholm 171 77 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,8,16]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.29210"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2012.48.1903"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.05.130"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-12-526"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-12-0740"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2004.07.004"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.635"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.21488"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejon.2010.12.005"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.794"},{"key":"e_1_2_7_12_1","unstructured":"CRU. 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