{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T20:44:55Z","timestamp":1768250695869,"version":"3.49.0"},"reference-count":42,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,6,21]],"date-time":"2017-06-21T00:00:00Z","timestamp":1498003200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2017,6,21]],"date-time":"2017-06-21T00:00:00Z","timestamp":1498003200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R37 CA070867"],"award-info":[{"award-number":["R37 CA070867"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 CA188214"],"award-info":[{"award-number":["R01 CA188214"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["UM1 CA182910"],"award-info":[{"award-number":["UM1 CA182910"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["and UM1 CA173640"],"award-info":[{"award-number":["and UM1 CA173640"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007208","name":"Vanderbilt-Ingram Cancer Center","doi-asserted-by":"publisher","award":["P30 CA68485"],"award-info":[{"award-number":["P30 CA68485"]}],"id":[{"id":"10.13039\/100007208","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int. J. Cancer"],"published-print":{"date-parts":[[2017,9,15]]},"DOI":"10.1002\/ijc.30812","type":"journal-article","created":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T01:10:57Z","timestamp":1496279457000},"page":"1130-1139","source":"Crossref","is-referenced-by-count":18,"title":["Evaluation of genetic variants in association with colorectal cancer risk and survival in Asians"],"prefix":"10.1002","volume":"141","author":[{"given":"Nan","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Medicine, Division of Epidemiology; Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine; Nashville TN"},{"name":"Department of General Surgery; Tangdu Hospital, Fourth Military Medical University; Xi'an China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingchang","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Epidemiology; Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine; Nashville TN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikhil K.","family":"Khankari","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Epidemiology; Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine; Nashville TN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jirong","family":"Long","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Epidemiology; Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine; Nashville TN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong-Lan","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Epidemiology; Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine; Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Epidemiology; Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine; Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-Tang","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Epidemiology; Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine; Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong-Bing","family":"Xiang","sequence":"additional","affiliation":[{"name":"Department of Epidemiology; Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine; Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao-Ou","family":"Shu","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Epidemiology; Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine; Nashville TN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1226-070X","authenticated-orcid":false,"given":"Wei","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Epidemiology; Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine; Nashville TN"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,6,21]]},"reference":[{"key":"10.1002\/ijc.30812-BIB0001|ijc30812-cit-0001","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1001\/jamaoncol.2015.0735","article-title":"The global burden of cancer 2013","volume":"1","author":"Fitzmaurice","year":"2015","journal-title":"JAMA Oncol"},{"key":"10.1002\/ijc.30812-BIB0002|ijc30812-cit-0002","doi-asserted-by":"crossref","first-page":"10442","DOI":"10.1038\/srep10442","article-title":"A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer","volume":"5","author":"Al-Tassan","year":"2015","journal-title":"Sci Rep"},{"key":"10.1002\/ijc.30812-BIB0003|ijc30812-cit-0003","doi-asserted-by":"crossref","first-page":"4729","DOI":"10.1093\/hmg\/ddu177","article-title":"Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis","volume":"23","author":"Whiffin","year":"2014","journal-title":"Hum Mol Genet"},{"key":"10.1002\/ijc.30812-BIB0004|ijc30812-cit-0004","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1038\/ng.670","article-title":"Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33","volume":"42","author":"Houlston","year":"2010","journal-title":"Nat Genet"},{"key":"10.1002\/ijc.30812-BIB0005|ijc30812-cit-0005","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1053\/j.gastro.2012.12.020","article-title":"Identification of genetic susceptibility loci for colorectal tumors in a genome-wide meta-analysis","volume":"144","author":"Peters","year":"2013","journal-title":"Gastroenterology"},{"key":"10.1002\/ijc.30812-BIB0006|ijc30812-cit-0006","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.1093\/hmg\/ddw087","article-title":"Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease","volume":"25","author":"Orlando","year":"2016","journal-title":"Hum Mol Genet"},{"key":"10.1002\/ijc.30812-BIB0007|ijc30812-cit-0007","doi-asserted-by":"crossref","first-page":"7138","DOI":"10.1038\/ncomms8138","article-title":"Genome-wide association study of colorectal cancer identifies six new susceptibility loci","volume":"6","author":"Schumacher","year":"2015","journal-title":"Nat Commun"},{"key":"10.1002\/ijc.30812-BIB0008|ijc30812-cit-0008","doi-asserted-by":"crossref","first-page":"2512","DOI":"10.1093\/carcin\/bgu148","article-title":"A novel colorectal cancer risk locus at 4q32.2 identified from an international genome-wide association study","volume":"35","author":"Schmit","year":"2014","journal-title":"Carcinogenesis"},{"key":"10.1002\/ijc.30812-BIB0009|ijc30812-cit-0009","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1038\/ng.2505","article-title":"Genome-wide association analyses in East Asians identify new susceptibility loci for colorectal cancer","volume":"45","author":"Jia","year":"2013","journal-title":"Nat Genet"},{"key":"10.1002\/ijc.30812-BIB0010|ijc30812-cit-0010","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1038\/ng.2293","article-title":"Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk","volume":"44","author":"Dunlop","year":"2012","journal-title":"Nat Genet"},{"key":"10.1002\/ijc.30812-BIB0011|ijc30812-cit-0011","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1053\/j.gastro.2016.02.076","article-title":"Identification of susceptibility loci and genes for colorectal cancer risk","volume":"150","author":"Zeng","year":"2016","journal-title":"Gastroenterology"},{"key":"10.1002\/ijc.30812-BIB0012|ijc30812-cit-0012","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1136\/gut.2010.215947","article-title":"Common variant in 6q26-q27 is associated with distal colon cancer in an Asian population","volume":"60","author":"Cui","year":"2011","journal-title":"Gut"},{"key":"10.1002\/ijc.30812-BIB0013|ijc30812-cit-0013","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1038\/ng.111","article-title":"A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3","volume":"40","author":"Tomlinson","year":"2008","journal-title":"Nat Genet"},{"key":"10.1002\/ijc.30812-BIB0014|ijc30812-cit-0014","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1038\/ng2085","article-title":"A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21","volume":"39","author":"Tomlinson","year":"2007","journal-title":"Nat Genet"},{"key":"10.1002\/ijc.30812-BIB0015|ijc30812-cit-0015","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1038\/ng2089","article-title":"Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24","volume":"39","author":"Zanke","year":"2007","journal-title":"Nat Genet"},{"key":"10.1002\/ijc.30812-BIB0016|ijc30812-cit-0016","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1038\/ng.133","article-title":"Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21","volume":"40","author":"Tenesa","year":"2008","journal-title":"Nat Genet"},{"key":"10.1002\/ijc.30812-BIB0017|ijc30812-cit-0017","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1038\/ng.2985","article-title":"Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk","volume":"46","author":"Zhang","year":"2014","journal-title":"Nat Genet"},{"key":"10.1002\/ijc.30812-BIB0018|ijc30812-cit-0018","doi-asserted-by":"crossref","first-page":"4613","DOI":"10.1038\/ncomms5613","article-title":"Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A","volume":"5","author":"Wang","year":"2014","journal-title":"Nat Commun"},{"key":"10.1002\/ijc.30812-BIB0019|ijc30812-cit-0019","doi-asserted-by":"crossref","first-page":"11478","DOI":"10.1038\/ncomms11478","article-title":"Common genetic variation in ETV6 is associated with colorectal cancer susceptibility","volume":"7","author":"Wang","year":"2016","journal-title":"Nat Commun"},{"key":"10.1002\/ijc.30812-BIB0020|ijc30812-cit-0020","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1038\/ng.262","article-title":"Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer","volume":"40","author":"Houlston","year":"2008","journal-title":"Nat Genet"},{"key":"10.1002\/ijc.30812-BIB0021|ijc30812-cit-0021","doi-asserted-by":"crossref","first-page":"e1002105","DOI":"10.1371\/journal.pgen.1002105","article-title":"Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer","volume":"7","author":"Tomlinson","year":"2011","journal-title":"PLoS Genet"},{"key":"10.1002\/ijc.30812-BIB0022|ijc30812-cit-0022","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1038\/ng.2007.41","article-title":"Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk","volume":"40","author":"Jaeger","year":"2008","journal-title":"Nat Genet"},{"key":"10.1002\/ijc.30812-BIB0023|ijc30812-cit-0023","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1002\/ijc.28733","article-title":"Genome-wide association study identifies a new SMAD7 risk variant associated with colorectal cancer risk in East Asians","volume":"135","author":"Zhang","year":"2014","journal-title":"Int J Cancer"},{"key":"10.1002\/ijc.30812-BIB0024|ijc30812-cit-0024","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1038\/ng.2007.18","article-title":"A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk","volume":"39","author":"Broderick","year":"2007","journal-title":"Nat Genet"},{"key":"10.1002\/ijc.30812-BIB0025|ijc30812-cit-0025","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/s00439-011-1055-0","article-title":"Meta-analysis of new genome-wide association studies of colorectal cancer risk","volume":"131","author":"Peters","year":"2012","journal-title":"Hum Genet"},{"key":"10.1002\/ijc.30812-BIB0026|ijc30812-cit-0026","first-page":"1699","article-title":"GWAS-identified colorectal cancer susceptibility locus associates with disease prognosis","volume":"47","author":"Xing","year":"2011","journal-title":"Eur J Cancer Oxf Engl 1990"},{"key":"10.1002\/ijc.30812-BIB0027|ijc30812-cit-0027","doi-asserted-by":"crossref","first-page":"3754","DOI":"10.1158\/1078-0432.CCR-10-0439","article-title":"Ten common genetic variants associated with colorectal cancer risk are not associated with survival after diagnosis","volume":"16","author":"Tenesa","year":"2010","journal-title":"Clin Cancer Res Off J Am Assoc Cancer Res"},{"key":"10.1002\/ijc.30812-BIB0028|ijc30812-cit-0028","doi-asserted-by":"crossref","first-page":"e41954","DOI":"10.1371\/journal.pone.0041954","article-title":"Association of eleven common, low-penetrance colorectal cancer susceptibility genetic variants at six risk loci with clinical outcome","volume":"7","author":"Hoskins","year":"2012","journal-title":"PLoS One"},{"key":"10.1002\/ijc.30812-BIB0029|ijc30812-cit-0029","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1053\/j.gastro.2012.04.052","article-title":"Association between colorectal cancer susceptibility loci and survival time after diagnosis with colorectal cancer","volume":"143","author":"Phipps","year":"2012","journal-title":"Gastroenterology"},{"key":"10.1002\/ijc.30812-BIB0030|ijc30812-cit-0030","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1093\/carcin\/bgs147","article-title":"GWAS-identified colorectal cancer susceptibility loci associated with clinical outcomes","volume":"33","author":"Dai","year":"2012","journal-title":"Carcinogenesis"},{"key":"10.1002\/ijc.30812-BIB0031|ijc30812-cit-0031","doi-asserted-by":"crossref","first-page":"e0117816","DOI":"10.1371\/journal.pone.0117816","article-title":"A retrospective observational study of the relationship between single nucleotide polymorphisms associated with the risk of developing colorectal cancer and survival","volume":"10","author":"Morris","year":"2015","journal-title":"PLoS One"},{"key":"10.1002\/ijc.30812-BIB0032|ijc30812-cit-0032","doi-asserted-by":"crossref","first-page":"e0119649","DOI":"10.1371\/journal.pone.0119649","article-title":"Association between GWAS-identified genetic variations and disease prognosis for patients with colorectal cancer","volume":"10","author":"Kang","year":"2015","journal-title":"PLoS One"},{"key":"10.1002\/ijc.30812-BIB0033|ijc30812-cit-0033","doi-asserted-by":"crossref","first-page":"3453","DOI":"10.1158\/1078-0432.CCR-14-3136","article-title":"Analyses of 7,635 patients with colorectal cancer using independent training and validation cohorts show that rs9929218 in CDH1 is a prognostic marker of survival","volume":"21","author":"Smith","year":"2015","journal-title":"Clin Cancer Res Off J Am Assoc Cancer Res"},{"key":"10.1002\/ijc.30812-BIB0034|ijc30812-cit-0034","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1093\/aje\/kwi322","article-title":"The Shanghai Women's Health Study: rationale, study design, and baseline characteristics","volume":"162","author":"Zheng","year":"2005","journal-title":"Am J Epidemiol"},{"key":"10.1002\/ijc.30812-BIB0035|ijc30812-cit-0035","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1093\/ije\/dyv013","article-title":"Cohort Profile: The Shanghai Men's Health Study","volume":"44","author":"Shu","year":"2015","journal-title":"Int J Epidemiol"},{"key":"10.1002\/ijc.30812-BIB0036|ijc30812-cit-0036","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1053\/j.gastro.2015.02.010","article-title":"A model to determine colorectal cancer risk using common genetic susceptibility loci","volume":"148","author":"Hsu","year":"2015","journal-title":"Gastroenterology"},{"key":"10.1002\/ijc.30812-BIB0037|ijc30812-cit-0037","doi-asserted-by":"crossref","first-page":"175","DOI":"10.5808\/GI.2012.10.3.175","article-title":"Prediction of colorectal cancer risk using a genetic risk score: The Korean Cancer Prevention Study-II (KCPS-II)","volume":"10","author":"Jo","year":"2012","journal-title":"Genomics Inform"},{"key":"10.1002\/ijc.30812-BIB0038|ijc30812-cit-0038","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1038\/ng.403","article-title":"The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer","volume":"41","author":"Pomerantz","year":"2009","journal-title":"Nat Genet"},{"key":"10.1002\/ijc.30812-BIB0039|ijc30812-cit-0039","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1186\/1471-2407-10-670","article-title":"Characterization of the association between 8q24 and colon cancer: gene-environment exploration and meta-analysis","volume":"10","author":"Hutter","year":"2010","journal-title":"BMC Cancer"},{"key":"10.1002\/ijc.30812-BIB0040|ijc30812-cit-0040","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1038\/ng.406","article-title":"The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling","volume":"41","author":"Tuupanen","year":"2009","journal-title":"Nat Genet"},{"key":"10.1002\/ijc.30812-BIB0041|ijc30812-cit-0041","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1053\/j.gastro.2012.09.016","article-title":"Much of the genetic risk of colorectal cancer is likely to be mediated through susceptibility to adenomas","volume":"144","author":"Carvajal-Carmona","year":"2013","journal-title":"Gastroenterology"},{"key":"10.1002\/ijc.30812-BIB0042|ijc30812-cit-0042","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1093\/carcin\/bgs357","article-title":"BMP2\/BMP4 colorectal cancer susceptibility loci in northern and southern European populations","volume":"34","author":"Fernandez-Rozadilla","year":"2013","journal-title":"Carcinogenesis"}],"container-title":["International Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fijc.30812","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/ijc.30812","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T20:30:04Z","timestamp":1625171404000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ijc.30812"}},"subtitle":["GWAS identified SNPS and CRC risk and survival"],"short-title":[],"issued":{"date-parts":[[2017,6,21]]},"references-count":42,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,9,15]]}},"URL":"https:\/\/doi.org\/10.1002\/ijc.30812","archive":["Portico"],"relation":{},"ISSN":["0020-7136"],"issn-type":[{"value":"0020-7136","type":"print"}],"subject":[],"published":{"date-parts":[[2017,6,21]]}}}