{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T21:56:29Z","timestamp":1790373389568,"version":"4.1.0"},"reference-count":35,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,10,9]],"date-time":"2017-10-09T00:00:00Z","timestamp":1507507200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100006364","name":"Institut National Du Cancer","doi-asserted-by":"publisher","award":["INCa_11338"],"award-info":[{"award-number":["INCa_11338"]}],"id":[{"id":"10.13039\/501100006364","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:p>Some previous epidemiological studies have suggested that pesticide exposure during pregnancy may have a possible role in the development of childhood brain tumors (CBT). We pooled data from two French national population\u2010based, case\u2013control studies to investigate the association between maternal residential use of pesticides during pregnancy and the risk of CBT. The mothers of 437 CBT cases and 3,102 controls aged under 15 years who resided in France at diagnosis\/interview, frequency\u2010matched by age and gender, answered a structured telephone interview conducted by trained interviewers. Unconditional logistic regression was used to estimate pooled odds ratio (OR) and 95% confidence intervals (95% CI). CBT was significantly associated with the maternal home use of pesticides during pregnancy (OR 1.4, 95% CI 1.2\u20131.8) and, more specifically, with insecticide (OR 1.4, 1.2\u20131.8). We could not draw any conclusions about herbicides and\/or fungicides because few women used them during pregnancy and most of these mothers also used insecticides. Although potential recall bias cannot be excluded, our findings of this pooled analysis support the hypothesis that residential maternal use of pesticides during pregnancy and particularly insecticides may increase the risk of CBT. Future investigations to verify these findings and to explore for CBT subtypes and dose\u2013response are necessary to have a better understanding of the possible role of pesticides in etiology of CBT.<\/jats:p>","DOI":"10.1002\/ijc.31073","type":"journal-article","created":{"date-parts":[[2017,9,26]],"date-time":"2017-09-26T08:47:53Z","timestamp":1506415673000},"page":"489-497","source":"Crossref","is-referenced-by-count":30,"title":["Maternal residential pesticide use during pregnancy and risk of malignant childhood brain tumors: A pooled analysis of the ESCALE and ESTELLE studies (SFCE)"],"prefix":"10.1002","volume":"142","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5511-6746","authenticated-orcid":false,"given":"Nicolas","family":"Vidart d'Egurbide Bagazgo\u00eftia","sequence":"first","affiliation":[{"name":"INSERM, Universit\u00e9 Paris\u2010Descartes, Universit\u00e9 Sorbonne\u2010Paris\u2010Cit\u00e9, CRESS\u2010EPICEA Epid\u00e9miologie des cancers de l'enfant et de l'adolescent Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1259-3793","authenticated-orcid":false,"given":"Helen D.","family":"Bailey","sequence":"additional","affiliation":[{"name":"INSERM, Universit\u00e9 Paris\u2010Descartes, Universit\u00e9 Sorbonne\u2010Paris\u2010Cit\u00e9, CRESS\u2010EPICEA Epid\u00e9miologie des cancers de l'enfant et de l'adolescent Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9332-3620","authenticated-orcid":false,"given":"Laurent","family":"Orsi","sequence":"additional","affiliation":[{"name":"INSERM, Universit\u00e9 Paris\u2010Descartes, Universit\u00e9 Sorbonne\u2010Paris\u2010Cit\u00e9, CRESS\u2010EPICEA Epid\u00e9miologie des cancers de l'enfant et de l'adolescent Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brigitte","family":"Lacour","sequence":"additional","affiliation":[{"name":"INSERM, Universit\u00e9 Paris\u2010Descartes, Universit\u00e9 Sorbonne\u2010Paris\u2010Cit\u00e9, CRESS\u2010EPICEA Epid\u00e9miologie des cancers de l'enfant et de l'adolescent Paris France"},{"name":"RNCE \u2013 National Registry of Childhood Cancers, Inserm, Villejuif and CHU de Nancy  France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L\u00e9a","family":"Guerrini\u2010Rousseau","sequence":"additional","affiliation":[{"name":"Gustave Roussy, D\u00e9partement de canc\u00e9rologie de l'enfant et de l'adolescent Villejuif France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne\u2010Isabelle","family":"Bertozzi","sequence":"additional","affiliation":[{"name":"Unit\u00e9 d'H\u00e9mato\u2010Immuno\u2010Oncologie p\u00e9diatrique, P\u00f4le P\u00e9diatrique, CHU Toulouse  France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Leblond","sequence":"additional","affiliation":[{"name":"Pediatric Oncology Unit, Oscar Lambret 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