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The Janus Cohort, including 292,851 Norwegians recruited 1972\u20132003, was linked to the Cancer Registry of Norway and followed for CM through 2014. Cox regression was used to estimate hazard ratios (HRs) of CM with 95% confidence intervals (CIs). Restricted cubic splines were incorporated into the Cox models to assess possible non\u2010linear relationships. All analyses were adjusted for attained age, indicators of UVR exposure, education, and smoking status. During a mean follow\u2010up of 27 years, 3,000 incident CM cases were identified. In men, CM risk was positively associated with body mass index, body surface area (BSA), height and weight (all <jats:italic>p<\/jats:italic><jats:sub>trends<\/jats:sub>\u2009&lt;\u20090.001), and the exposure\u2010response curves indicated an exponential increase in risk for all anthropometric factors. Weight loss of more than 2 kg in men was associated with a 53% lower risk (HR 0.47, 95% CI: 0.39, 0.57). In women, CM risk increased with increasing BSA (<jats:italic>p<\/jats:italic><jats:sub>trend<\/jats:sub>\u2009=\u20090.002) and height (<jats:italic>p<\/jats:italic><jats:sub>trend<\/jats:sub>\u2009&lt;\u20090.001). The shape of the height\u2010CM risk curve indicated an exponential increase. Our study suggests that large body size, in general, is a CM risk factor in men, and is the first to report that weight loss may reduce the risk of CM among men.<\/jats:p>","DOI":"10.1002\/ijc.31086","type":"journal-article","created":{"date-parts":[[2017,10,6]],"date-time":"2017-10-06T08:42:42Z","timestamp":1507279362000},"page":"681-690","source":"Crossref","is-referenced-by-count":14,"title":["Anthropometric factors and cutaneous melanoma: Prospective data from the population\u2010based Janus Cohort"],"prefix":"10.1002","volume":"142","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1964-5410","authenticated-orcid":false,"given":"Jo S","family":"Stenehjem","sequence":"first","affiliation":[{"name":"Department of Research Cancer Registry of Norway Oslo Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2083-2758","authenticated-orcid":false,"given":"Marit B","family":"Veier\u00f8d","sequence":"additional","affiliation":[{"name":"Oslo Center for Biostatistics and Epidemiology, Department of Biostatistics University of Oslo Oslo Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lill Tove","family":"Nilsen","sequence":"additional","affiliation":[{"name":"Norwegian Radiation Protection Authority \u00d8ster\u00e5s Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reza","family":"Ghiasvand","sequence":"additional","affiliation":[{"name":"Oslo Center for Biostatistics and Epidemiology, Department of Biostatistics University of Oslo Oslo Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bj\u00f8rn","family":"Johnsen","sequence":"additional","affiliation":[{"name":"Norwegian Radiation Protection Authority \u00d8ster\u00e5s Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom K","family":"Grimsrud","sequence":"additional","affiliation":[{"name":"Department of Research Cancer Registry of Norway Oslo Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronnie","family":"Babigumira","sequence":"additional","affiliation":[{"name":"Department of Research Cancer Registry of Norway Oslo Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith R","family":"Rees","sequence":"additional","affiliation":[{"name":"New Hampshire State Cancer Registry Lebanon NH"},{"name":"Department of Epidemiology Geisel School of Medicine at Dartmouth Lebanon NH"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1652-7734","authenticated-orcid":false,"given":"Trude E","family":"Robsahm","sequence":"additional","affiliation":[{"name":"Department of Research Cancer Registry of Norway Oslo Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,10,17]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2016.01.035"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.15510"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2012.12.027"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2011.489"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-22539-5_2"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canep.2015.12.006"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910550406"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0215(19970516)71:4<600::AID-IJC15>3.0.CO;2-F"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-006-0023-9"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annepidem.2007.09.003"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-012-9941-x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.cmr.0000194429.77643.76"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1011211615524"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwj115"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.23214"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2012.08.028"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-13-0647"},{"key":"e_1_2_6_19_1","first-page":"1101","article-title":"Cohort Profile Update: The Janus Serum Bank Cohort in Norway","volume":"46","author":"Hjerkind KV","year":"2017","journal-title":"Int J Epidemiol"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2016-014829"},{"key":"e_1_2_6_21_1","volume-title":"Geigy Scientific Tables. 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