{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T00:53:26Z","timestamp":1790384006135,"version":"4.1.0"},"reference-count":48,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,10,26]],"date-time":"2017-10-26T00:00:00Z","timestamp":1508976000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004586","name":"Funda\u00e7\u00e3o Carlos Chagas Filho de Amparo \u00e0 Pesquisa do Estado do Rio de Janeiro","doi-asserted-by":"publisher","award":["26\/102.977\/2012"],"award-info":[{"award-number":["26\/102.977\/2012"]}],"id":[{"id":"10.13039\/501100004586","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["440567\/2014\u20109"],"award-info":[{"award-number":["440567\/2014\u20109"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:p>\n                    Socioeconomic status (SES) is a well\u2010known determinant of outcomes in cancer. The purpose of this study was to analyze the impact of the SES on the outcomes of Hodgkin lymphoma (HL) patients from the Brazilian Prospective HL Registry. SES stratification was done using an individual asset\/education\u2010based household index. A total of 624 classical HL patients with diagnosis from January\/2009 to December\/2014, and treated with ABVD (doxorubicin, bleomycin, vinblastine and dacarbazine), were analyzed. The median follow\u2010up was 35.6 months, and 33% were classified as lower SES. The 3\u2010year progression\u2010 free survival (PFS) in higher and lower SES were 78 and 64% (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.0001), respectively. The 3\u2010year overall survival (OS) in higher and lower SES were 94 and 82% (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.0001), respectively. Lower SES patients were more likely to be\u2009\u2265\u200960 years (16\n                    <jats:italic>vs<\/jats:italic>\n                    . 8%,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.003), and to present higher risk International Prognostic score (IPS) (44\n                    <jats:italic>vs<\/jats:italic>\n                    . 31%,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.004) and advanced disease (71\n                    <jats:italic>vs<\/jats:italic>\n                    . 58%,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.003). After adjustments for potential confounders, lower SES remained independently associated with poorer survival (HR\u2009=\u20093.12 [1.86\u20105.22] for OS and HR\u2009=\u20091.66 [1.19\u20102.32] for PFS). The fatality ratio during treatment was 7.5 and 1.3% for lower and higher SES (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.0001). Infections and treatment toxicity accounted for 81% of these deaths. SES is an independent factor associated with shorter survival in HL in Brazil. Potential underlying mechanisms associated with the impact of SES are delayed diagnosis and poorer education. Educational and socio\u2010economic support interventions must be tested in this vulnerable population.\n                  <\/jats:p>","DOI":"10.1002\/ijc.31096","type":"journal-article","created":{"date-parts":[[2017,10,11]],"date-time":"2017-10-11T04:03:49Z","timestamp":1507694629000},"page":"883-890","source":"Crossref","is-referenced-by-count":25,"title":["Lower socioeconomic status is independently associated with shorter survival in Hodgkin Lymphoma patients\u2014An analysis from the Brazilian Hodgkin Lymphoma Registry"],"prefix":"10.1002","volume":"142","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7265-7691","authenticated-orcid":false,"given":"Irene","family":"Biasoli","sequence":"first","affiliation":[{"name":"School of Medicine, Universidade Federal do Rio de Janeiro Rio de Janeiro, Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nelson","family":"Castro","sequence":"additional","affiliation":[{"name":"Hospital de Cancer de Barretos Barretos, S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcia","family":"Delamain","sequence":"additional","affiliation":[{"name":"Hematology and Hemotherapy Center, University of Campinas Campinas, S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Talita","family":"Silveira","sequence":"additional","affiliation":[{"name":"S\u00e3o Paulo Santa Casa Medical School S\u00e3o Paulo, S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Farley","sequence":"additional","affiliation":[{"name":"Liga Norte Rio Grandense contra o c\u00e2ncer Natal, Rio Grande do Norte Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Belinda","family":"Pinto Sim\u00f5es","sequence":"additional","affiliation":[{"name":"USP\u2010Ribeir\u00e3o Preto Ribeir\u00e3o Preto, S\u00e3o Paulo 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