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A 4\u2010year cohort of women (<jats:italic>n<\/jats:italic>\u2009=\u2009820) with ASCUS\/LSIL and a positive HPV test in triage were followed for 6\u20139 years. The progression risks for CIN2+\/CIN3+ were determined for single (71.2%) and multiple HPV infections (28.8%). The CIN2+ progression risk for all HPV 16, all HPV 35, single HPV 16 and single HPV 35 infections were 65.3% (95% CI: 59.6\u201371.0), 64.4% (95% CI: 50.4\u201378.4), 63.8% (95% CI: 56.2\u201371.4) and 73.7% (95% CI: 53.9\u201393.5), respectively. Based on CIN2+ progression risks four main groups were defined; the HPV 16 group, the HPV 31\/33\/35 group, the HPV 18\/45\/51\/52 group and the HPV 39\/56\/58\/59\/66\/68 group with progression risks of 65.3% (95% CI: 59.6\u201371.0), 62.1% (95% CI: 54.8\u201369.4), 52.6 (95% CI: 45.9\u201359.3) and 39.5 (95% CI: 33.0\u201346.0), respectively. In multivariate analyses, women in the age group 40\u201349 years had an increased risk of CIN2+ progression. As for CIN3+, HPV 16 had a higher progression risk than other HPV risk groups (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). In multiple infections only HPV 16 had a significant additive CIN3+ progression risk (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05) as compared to other HPV risk groups. In summary, HPV types 16 and 35, including the HPV risk group 31\/33\/35, had a similar CIN2+ progression risk, but only HPV 16 had a higher risk for CIN3+ progression.<\/jats:p>","DOI":"10.1002\/ijc.31390","type":"journal-article","created":{"date-parts":[[2018,3,23]],"date-time":"2018-03-23T11:26:22Z","timestamp":1521804382000},"page":"851-860","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Human papillomavirus type specific risk of progression and remission during long\u2010term follow\u2010up of equivocal and low\u2010grade HPV\u2010positive cervical smears"],"prefix":"10.1002","volume":"143","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0459-7863","authenticated-orcid":false,"given":"Olav Karsten","family":"Vintermyr","sequence":"first","affiliation":[{"name":"Department of Pathology Haukeland University Hospital Bergen Norway"},{"name":"The Gade Laboratory for Pathology, Department of Clinical Medicine 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