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Further, for previously studied aspects, for example, tooth\u2010loss, the findings are inconsistent. We conducted a prospective cohort study of 19,831 participants from Uppsala, Sweden, cancer\u2010free at baseline in 1973\u20131974 and followed until 2012 through linkage to national registers. We found that individuals with fewest teeth at baseline had an increased risk of gastric cancer relative to subjects with all examined teeth present (<jats:italic>p<\/jats:italic> = 1.75e\u20102). Presence of denture\u2010associated lesions was also associated with an increased risk of gastric cancer (<jats:italic>p<\/jats:italic> = 1.00e\u20104). However, these excess risks significantly varied with attained age; estimated hazard ratio (HR) at attained age 50 for tooth loss was 4.24 [95% confidence interval (CI) 1.83\u20139.80] and 5.91 (95% CI 2.76\u201312.63) for denture\u2010associated lesions, decreasing at an estimated 4% and 6% per year respectively, resulting in HR of 1.54 (95% CI 0.90\u20132.64) for tooth loss and HR 1.29 (95% CI 0.90\u20131.85) for denture\u2010associated lesions at attained age 75. No increased risk of gastric cancer was found for individuals with higher levels of dental plaque, or with <jats:italic>Candida<\/jats:italic>\u2010related or tongue lesions. In conclusion, tooth\u2010loss and denture\u2010associated lesions are associated with increased risks of gastric cancer. Previous conflicting findings of tooth\u2010loss and gastric cancer risk may partly be explained by the age\u2010varying relative risk of gastric cancer.<\/jats:p>","DOI":"10.1002\/ijc.31614","type":"journal-article","created":{"date-parts":[[2018,6,6]],"date-time":"2018-06-06T07:00:48Z","timestamp":1528268448000},"page":"2281-2288","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Association between poor oral health and gastric cancer: A prospective cohort study"],"prefix":"10.1002","volume":"143","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5297-5107","authenticated-orcid":false,"given":"Nelson","family":"Ndegwa","sequence":"first","affiliation":[{"name":"Department of Medical Epidemiology and Biostatistics Karolinska Institutet Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Ploner","sequence":"additional","affiliation":[{"name":"Department of Medical 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