{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T22:45:58Z","timestamp":1791585958504,"version":"4.3.4"},"reference-count":7,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2018,12,4]],"date-time":"2018-12-04T00:00:00Z","timestamp":1543881600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["P01CA055075, R01HL035464, U01CA167552"],"award-info":[{"award-number":["P01CA055075, R01HL035464, U01CA167552"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30CA006973, P50CA58236"],"award-info":[{"award-number":["P30CA006973, P50CA58236"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000892","name":"Prostate Cancer Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000892","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2019,5,15]]},"abstract":"<jats:p>\n                    We previously observed a positive association between seropositivity for the parasite\n                    <jats:italic>Trichomonas vaginalis<\/jats:italic>\n                    and risk of clinically significant prostate cancer at diagnosis. Here, we examined whether\n                    <jats:italic>T. vaginalis<\/jats:italic>\n                    seropositivity was associated with increased prostate cancer\u2010specific or all\u2010cause mortality among prostate cancer patients. We studied 736 men with prostate cancer from the Physicians\u2019 Health Study (PHS) and 749 men with prostate cancer from the Health Professionals Follow\u2010Up Study (HPFS). We used Cox proportional hazards regression models to estimate multivariable\u2010adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) of the association between\n                    <jats:italic>T. vaginalis<\/jats:italic>\n                    serostatus and progression to death from prostate cancer and from all causes. In PHS, 423 men died of any cause during a median follow\u2010up of 13.8 years from the date of cancer diagnosis, among whom 131 died of prostate cancer. In HPFS, there were 287 deaths, including 77 deaths from prostate cancer, during a median follow\u2010up of 12.8 years. We found no association between\n                    <jats:italic>T. vaginalis<\/jats:italic>\n                    serostatus and either prostate cancer mortality or all\u2010cause mortality in either the PHS or HPFS. While previous studies suggest a possible role for\n                    <jats:italic>T. vaginalis<\/jats:italic>\n                    in the development of clinically significant prostate cancer, our findings do not support the hypothesis that\n                    <jats:italic>T. vaginalis<\/jats:italic>\n                    serostatus is associated with mortality among prostate cancer patients.\n                  <\/jats:p>","DOI":"10.1002\/ijc.31885","type":"journal-article","created":{"date-parts":[[2018,9,22]],"date-time":"2018-09-22T11:53:50Z","timestamp":1537617230000},"page":"2377-2380","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Association between\n                    <i>Trichomonas vaginalis<\/i>\n                    and prostate cancer mortality"],"prefix":"10.1002","volume":"144","author":[{"given":"Sabrina H.","family":"Tsang","sequence":"first","affiliation":[{"name":"Cancer Prevention Fellowship Program, Division of Cancer Epidemiology and Genetics National Cancer Institute  Bethesda MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel F.","family":"Peisch","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Harvard T.H. Chan School of Public Health  Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brendan","family":"Rowan","sequence":"additional","affiliation":[{"name":"UCD School of Medicine, University College Dublin  Belfield, Dublin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah C.","family":"Markt","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Harvard T.H. Chan School of Public Health  Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amparo G.","family":"Gonzalez\u2010Feliciano","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Harvard T.H. Chan School of Public Health  Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siobhan","family":"Sutcliffe","sequence":"additional","affiliation":[{"name":"Division of Public Health Sciences, Department of Surgery Washington University School of Medicine  Saint Louis MO"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth A.","family":"Platz","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Johns Hopkins Bloomberg School of Public Health  Baltimore MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorelei A.","family":"Mucci","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Harvard T.H. Chan School of Public Health  Boston MA"},{"name":"Channing Division of Network Medicine, Department of Medicine Brigham and Women's Hospital and Harvard Medical School  Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7144-693X","authenticated-orcid":false,"given":"Ericka M.","family":"Ebot","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Harvard T.H. Chan School of Public Health  Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,12,4]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-05-0781"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djp306"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.24144"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/pros.23153"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13104-016-2033-3"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-017-0919-6"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00582-13"}],"container-title":["International Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fijc.31885","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.31885","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ijc.31885","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.31885","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T01:17:36Z","timestamp":1692494256000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ijc.31885"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,4]]},"references-count":7,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2019,5,15]]}},"alternative-id":["10.1002\/ijc.31885"],"URL":"https:\/\/doi.org\/10.1002\/ijc.31885","archive":["Portico"],"relation":{},"ISSN":["0020-7136","1097-0215"],"issn-type":[{"value":"0020-7136","type":"print"},{"value":"1097-0215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,12,4]]},"assertion":[{"value":"2018-06-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-08-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-12-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}