{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T07:06:36Z","timestamp":1772694396459,"version":"3.50.1"},"reference-count":41,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,12,20]],"date-time":"2018-12-20T00:00:00Z","timestamp":1545264000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2019,3,15]]},"abstract":"<jats:p>Little is known about the effect of evolving risk\u2010based cervical cancer screening and management guidelines on United States (US) clinical practice and patient outcomes. We describe the National Cancer Institute's Population\u2010based Research Optimizing Screening through Personalized Regimens (PROSPR I) consortium, methods and baseline findings from its cervical sites: Kaiser Permanente Washington, Kaiser Permanente Northern California, Kaiser Permanente Southern California, Parkland Health &amp; Hospital System\/University of Texas Southwestern (Parkland\u2010UTSW) and New Mexico HPV Pap Registry housed by University of New Mexico (UNM\u2010NMHPVPR). Across these diverse healthcare settings, we collected data on human papillomavirus (HPV) vaccinations, screening tests\/results, diagnostic and treatment procedures\/results and cancer diagnoses on nearly 4.7 million women aged 18\u201389 years from 2010 to 2014. We calculated baseline (2012 for UNM\u2010NMHPVPR; 2010 for other sites) frequencies for sociodemographics, cervical cancer risk factors and key screening process measures for each site's cohort. Healthcare delivery settings, cervical cancer screening strategy, race\/ethnicity and insurance status varied among sites. The proportion of women receiving a Pap test during the baseline year was similar across sites (26.1\u201336.1%). Most high\u2010risk HPV tests were performed either reflexively or as cotests, and utilization pattern varied by site. Prevalence of colposcopy or biopsy was higher at Parkland\u2010UTSW (3.6%) than other sites (1.3\u20131.4%). Incident cervical cancer was rare. HPV vaccination among age\u2010eligible women not already immunized was modest across sites (0.1\u20137.2%). Cervical PROSPR I makes available high\u2010quality, multilevel, longitudinal screening process data from a large and diverse cohort of women to evaluate and improve the effectiveness of US cervical cancer screening delivery.<\/jats:p>","DOI":"10.1002\/ijc.31940","type":"journal-article","created":{"date-parts":[[2018,10,24]],"date-time":"2018-10-24T20:40:54Z","timestamp":1540413654000},"page":"1460-1473","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Cervical cancer screening research in the PROSPR I consortium: Rationale, methods and baseline findings from a US cohort"],"prefix":"10.1002","volume":"144","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0763-989X","authenticated-orcid":false,"given":"Aruna","family":"Kamineni","sequence":"first","affiliation":[{"name":"Kaiser Permanente Washington Health Research Institute  Seattle WA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jasmin A.","family":"Tiro","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences University of Texas Southwestern Medical Center  Dallas TX"},{"name":"Simmons Comprehensive Cancer Center  Dallas TX"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabeth F.","family":"Beaber","sequence":"additional","affiliation":[{"name":"Public Health Sciences Division Fred Hutchinson Cancer Research Center  Seattle WA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael J.","family":"Silverberg","sequence":"additional","affiliation":[{"name":"Division of Research Kaiser Permanente Northern California  Oakland CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cosette M.","family":"Wheeler","sequence":"additional","affiliation":[{"name":"University of New Mexico Comprehensive Cancer Center  Albuquerque NM"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chun R.","family":"Chao","sequence":"additional","affiliation":[{"name":"Department of Research and Evaluation Kaiser Permanente Southern California  Pasadena CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica","family":"Chubak","sequence":"additional","affiliation":[{"name":"Kaiser Permanente Washington Health Research Institute  Seattle WA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Celette Sugg","family":"Skinner","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences University of Texas Southwestern Medical Center  Dallas TX"},{"name":"Simmons Comprehensive Cancer Center  Dallas TX"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas A.","family":"Corley","sequence":"additional","affiliation":[{"name":"Division of Research Kaiser Permanente Northern California  Oakland CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jane J.","family":"Kim","sequence":"additional","affiliation":[{"name":"Center for Health Decision Science Harvard T.H. Chan School of Public Health  Boston MA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bijal A.","family":"Balasubramanian","sequence":"additional","affiliation":[{"name":"Simmons Comprehensive Cancer Center  Dallas TX"},{"name":"UTHealth School of Public Health in Dallas  Dallas TX"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Paul Doria\u2010Rose","sequence":"additional","affiliation":[{"name":"Division of Cancer Control and Population Sciences National Cancer Institute  Bethesda MD"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"on behalf of the PROSPR consortium","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,12,20]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djv120"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.3322\/canjclin.49.1.8"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.11380"},{"key":"e_1_2_7_5_1","volume-title":"World Health Organization. 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