{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T05:37:23Z","timestamp":1775885843343,"version":"3.50.1"},"reference-count":34,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2019,2,25]],"date-time":"2019-02-25T00:00:00Z","timestamp":1551052800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["552429"],"award-info":[{"award-number":["552429"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:p>The International Agency for Research on Cancer first concluded that alcohol causes cancer in humans in 1988. The World Cancer Research Fund has declared that alcohol causes cancer of the oral cavity, pharynx, larynx, oesophagus (squamous cell carcinoma), female breast, colon, rectum, stomach and liver. It recommended that alcohol be avoided altogether to prevent cancer. We aimed to quantify the impact of reducing alcohol consumption on future cancer incidence in Australia. We used PREVENT 3.01 simulation modelling software to estimate the proportion of cancers that could potentially be prevented over a 25\u2010year period under two hypothetical intervention scenarios and two latency periods (20 and 30\u2009years). Under a scenario where alcohol consumption abruptly ceases, we estimated up to 4% of alcohol\u2010related cancers could be avoided over a 25\u2010year period (~49,500 cancers, depending on assumed latency). If the maximum consumption of all Australian adults was \u226420\u2009g\/day (~two Australian standard drinks), up to 2% of alcohol\u2010related cancers could be avoided (~29,600 cancers). The maximum proportions were higher for men (6% for no alcohol consumption; 5% for \u226420\u2009g\/day) than women (3%; 1%). The proportion avoidable was highest for oesophageal squamous cell carcinoma (17% no alcohol consumption; 9% \u226420\u2009g\/day), followed by cancers of the oral cavity (12%; 5%) and pharynx (11%; 5%). The cancer sites with the highest numbers of potentially avoidable cases were colon in men (11,500; 9,900) and breast in women (14,400; 4,100). Successful interventions to reduce alcohol intake could lead to significant reductions in cancer incidence.<\/jats:p>","DOI":"10.1002\/ijc.32204","type":"journal-article","created":{"date-parts":[[2019,2,12]],"date-time":"2019-02-12T18:07:03Z","timestamp":1549994823000},"page":"2944-2953","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["The impact of reducing alcohol consumption in Australia: An estimate of the proportion of potentially avoidable cancers 2013\u20132037"],"prefix":"10.1002","volume":"145","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8709-8968","authenticated-orcid":false,"given":"Louise F.","family":"Wilson","sequence":"first","affiliation":[{"name":"Population Health Department QIMR Berghofer Medical Research Institute  Herston QLD Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter D.","family":"Baade","sequence":"additional","affiliation":[{"name":"Cancer Council Queensland  Fortitude Valley QLD Australia"},{"name":"Menzies Health Institute Queensland Griffith University, Gold Coast Campus  Southport QLD Australia"},{"name":"School of Mathematical Sciences Queensland University of Technology  Brisbane QLD Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adele C.","family":"Green","sequence":"additional","affiliation":[{"name":"Population Health Department QIMR Berghofer Medical Research Institute  Herston QLD Australia"},{"name":"The University of Queensland Faculty of Medicine  Herston QLD Australia"},{"name":"Cancer Research UK Manchester Institute and Division of Musculoskeletal &amp; Dermatological Sciences University of Manchester  Manchester United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan J.","family":"Jordan","sequence":"additional","affiliation":[{"name":"Population Health Department QIMR Berghofer Medical Research Institute  Herston QLD Australia"},{"name":"The University of Queensland Faculty of Medicine  Herston QLD Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bradley J.","family":"Kendall","sequence":"additional","affiliation":[{"name":"Population Health Department QIMR Berghofer Medical Research Institute  Herston QLD Australia"},{"name":"The University of Queensland Faculty of Medicine  Herston QLD Australia"},{"name":"Department of Gastroenterology and Hepatology Princess Alexandra Hospital  Brisbane QLD Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel E.","family":"Neale","sequence":"additional","affiliation":[{"name":"Population Health Department QIMR Berghofer Medical Research Institute  Herston QLD Australia"},{"name":"The University of Queensland Faculty of Medicine  Herston QLD Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine M.","family":"Olsen","sequence":"additional","affiliation":[{"name":"Population Health Department QIMR Berghofer Medical Research Institute  Herston QLD Australia"},{"name":"The University of Queensland Faculty of Medicine  Herston QLD Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2721-9083","authenticated-orcid":false,"given":"Danny R.","family":"Youlden","sequence":"additional","affiliation":[{"name":"Cancer Council Queensland  Fortitude Valley QLD Australia"},{"name":"Menzies Health Institute Queensland Griffith University, Gold Coast Campus  Southport QLD Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Penelope M.","family":"Webb","sequence":"additional","affiliation":[{"name":"Population Health Department QIMR Berghofer Medical Research Institute  Herston QLD Australia"},{"name":"The University of Queensland Faculty of Medicine  Herston QLD Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David C.","family":"Whiteman","sequence":"additional","affiliation":[{"name":"Population Health Department QIMR Berghofer Medical Research Institute  Herston QLD Australia"},{"name":"The University of Queensland Faculty of Medicine  Herston QLD Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,2,25]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"IARC monographs on the evaluation of the carcinogenic risks to humans. 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