{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T18:18:30Z","timestamp":1777486710266,"version":"3.51.4"},"reference-count":28,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2019,10,18]],"date-time":"2019-10-18T00:00:00Z","timestamp":1571356800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["R01\u2010CA\u2010230331"],"award-info":[{"award-number":["R01\u2010CA\u2010230331"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["R01\u2010CA\u2010085178"],"award-info":[{"award-number":["R01\u2010CA\u2010085178"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["R01\u2010CA\u2010174634"],"award-info":[{"award-number":["R01\u2010CA\u2010174634"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2020,6,15]]},"abstract":"<jats:p>Infection by human papillomavirus (HPV) type 16, the most oncogenic HPV type, was found to be the least affected by HIV\u2010status and CD4 count of any of the approximately 13 oncogenic HPV types. This relative independence from host immune status has been interpreted as evidence that HPV16 may have an innate ability to avoid the effects of immunosurveillance. However, the impact of immune status on other individual HPV types has not been carefully assessed. We studied type\u2010specific HPV infection in a cohort of 2,470 HIV\u2010positive (HIV[+]) and 895 HIV\u2010negative (HIV[\u2212]) women. Semi\u2010annually collected cervicovaginal lavages were tested for &gt;40 HPV types. HPV type\u2010specific prevalence ratios (PRs), incidence and clearance hazard ratios (HRs), were calculated by contrasting HPV types detected in HIV[+] women with CD4\u2009&lt;\u2009200 to HIV[\u2212] women. HPV71 and HPV16 prevalence had the weakest associations with HIV\u2010status\/CD4 count of any HPV, according to PRs. No correlations between PRs and HPV phylogeny or oncogenicity were observed. Instead, higher HPV type\u2010specific prevalence in HIV[\u2212] women correlated with lower PRs (\u03c1 = \u22120.59; <jats:italic>p<\/jats:italic> = 0.0001). An alternative (quadratic model) statistical approach (P<jats:sub>HIV+<\/jats:sub> = a*P<jats:sub>HIV\u2212<\/jats:sub>\u2009+\u2009b*P<jats:sub>HIV\u2212<\/jats:sub><jats:sup>2<\/jats:sup>; <jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup> = 0.894) found similar associations (<jats:italic>p<\/jats:italic> = 0.0005). In summary, the most prevalent HPV types in HIV[\u2212] women were the types most independent from host immune status. These results suggest that common HPV types in HIV[\u2212] women may have a greater ability to avoid immune surveillance than other types, which may help explain why they are common.<\/jats:p>","DOI":"10.1002\/ijc.32693","type":"journal-article","created":{"date-parts":[[2019,10,2]],"date-time":"2019-10-02T16:09:34Z","timestamp":1570032574000},"page":"3320-3328","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Epidemiological evidence that common HPV types may be common because of their ability to evade immune surveillance: Results from the Women's Interagency HIV study"],"prefix":"10.1002","volume":"146","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1082-6554","authenticated-orcid":false,"given":"Philip E.","family":"Castle","sequence":"first","affiliation":[{"name":"Albert Einstein College of Medicine  Bronx NY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8376-8458","authenticated-orcid":false,"given":"Robert D.","family":"Burk","sequence":"additional","affiliation":[{"name":"Albert Einstein College of Medicine  Bronx NY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8486-9464","authenticated-orcid":false,"given":"Leslie S.","family":"Massad","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine  St. Louis MO"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isam\u2010Eldin","family":"Eltoum","sequence":"additional","affiliation":[{"name":"University of Alabama  Birmingham AB"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles B.","family":"Hall","sequence":"additional","affiliation":[{"name":"Albert Einstein College of Medicine  Bronx NY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy A.","family":"Hessol","sequence":"additional","affiliation":[{"name":"University of California  San Francisco CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathryn","family":"Anastos","sequence":"additional","affiliation":[{"name":"Albert Einstein College of Medicine  Bronx NY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xianhong","family":"Xie","sequence":"additional","affiliation":[{"name":"Albert Einstein College of Medicine  Bronx NY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Howard","family":"Minkoff","sequence":"additional","affiliation":[{"name":"Maimonides Medical Center  Brooklyn NY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaonan","family":"Xue","sequence":"additional","affiliation":[{"name":"Albert Einstein College of Medicine  Bronx NY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gypsyamber","family":"D'Souza","sequence":"additional","affiliation":[{"name":"Johns Hopkins Bloomberg School of Public Health  Baltimore MD"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Flowers","sequence":"additional","affiliation":[{"name":"Emory University School of Medicine  Atlanta GA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Colie","sequence":"additional","affiliation":[{"name":"Georgetown University Medical Center  Washington DC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Rahangdale","sequence":"additional","affiliation":[{"name":"University of North Carolina School of Medicine  Chapel Hill NC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margaret A.","family":"Fischl","sequence":"additional","affiliation":[{"name":"University of Miami Miller School of Medicine  Miami FL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joel M.","family":"Palefsky","sequence":"additional","affiliation":[{"name":"University of California  San Francisco CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7692-6147","authenticated-orcid":false,"given":"Howard D.","family":"Strickler","sequence":"additional","affiliation":[{"name":"Albert Einstein College of Medicine  Bronx NY"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,10,18]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61416-0"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61050-2"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/95.14.1062"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2015.09.086"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.aids.0000253361.63578.14"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000001113"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(17)30653-9"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1128\/CDLI.12.9.1013-1019.2005"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.10220"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/civ569"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/dji073"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/174.4.679"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/91.3.226"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.35.6.1304-1310.1997"},{"key":"e_1_2_9_16_1","first-page":"566","article-title":"Elimination of false\u2010positive signals in enhanced chemiluminescence (ECL) detection of amplified HPV DNA from clinical samples","volume":"19","author":"Jiang G","year":"1995","journal-title":"Biotechniques"},{"key":"e_1_2_9_17_1","volume-title":"IARC Monographs on the Evaluation of Oncogenic Risks to Humans. Human Papillomaviruses [100B]","author":"IARC","year":"2012"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2010.02.002"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-09-0546"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1080\/01621459.1989.10478873"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.4780130402"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.1186"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000002005"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.28038"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1177\/0956462412474538"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1086\/340824"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.83178-0"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1086\/428779"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1086\/428850"}],"container-title":["International Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.32693","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ijc.32693","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.32693","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T12:24:14Z","timestamp":1693743854000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ijc.32693"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,18]]},"references-count":28,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2020,6,15]]}},"alternative-id":["10.1002\/ijc.32693"],"URL":"https:\/\/doi.org\/10.1002\/ijc.32693","archive":["Portico"],"relation":{},"ISSN":["0020-7136","1097-0215"],"issn-type":[{"value":"0020-7136","type":"print"},{"value":"1097-0215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,18]]},"assertion":[{"value":"2019-06-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-08-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}