{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T05:34:32Z","timestamp":1791005672568,"version":"4.1.0"},"reference-count":41,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2020,3,12]],"date-time":"2020-03-12T00:00:00Z","timestamp":1583971200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000278","name":"Department for International Development, UK Government","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000278","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007155","name":"Medical Research Council Canada","doi-asserted-by":"publisher","award":["MR\/J002380\/1"],"award-info":[{"award-number":["MR\/J002380\/1"]}],"id":[{"id":"10.13039\/501100007155","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","award":["U01\u2010AA026209"],"award-info":[{"award-number":["U01\u2010AA026209"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:p>People living with HIV (PLHIV) are more likely than the general population to develop AIDS\u2010defining malignancies (ADMs) and several non\u2010ADMs (NADMs). Information is lacking on survival outcomes and cause\u2010specific mortality after cancer diagnosis among PLHIV. We investigated causes of death within 5\u2009years of cancer diagnosis in PLHIV enrolled in European and North American HIV cohorts starting antiretroviral therapy (ART) 1996\u20132015, aged \u226516\u2009years, and subsequently diagnosed with cancer. Cancers were grouped: ADMs, viral NADMs and nonviral NADMs. We calculated cause\u2010specific mortality rates (MR) after diagnosis of specific cancers and compared 5\u2010year survival with the UK and France general populations. Among 83,856 PLHIV there were 4,436 cancer diagnoses. Of 603 deaths after ADM diagnosis, 292 (48%) were due to an ADM. There were 467\/847 (55%) and 74\/189 (39%) deaths that were due to an NADM after nonviral and viral NADM diagnoses, respectively. MR were higher for diagnoses between 1996 and 2005 <jats:italic>versus<\/jats:italic> 2006\u20132015: ADMs 102 (95% CI 92\u2013113) per 1,000\u2009years <jats:italic>versus<\/jats:italic> 88 (78\u2013100), viral NADMs 134 (106\u2013169) <jats:italic>versus<\/jats:italic> 111 (93\u2013133) and nonviral NADMs 264 (232\u2013300) <jats:italic>versus<\/jats:italic> 226 (206\u2013248). Estimated 5\u2010year survival for PLHIV diagnosed with liver (29% [19\u201339%]), lung (18% [13\u201323%]) and cervical (75% [63\u201384%]) cancer was similar to general populations. Survival after Hodgkin's lymphoma diagnosis was lower in PLHIV (75% [67\u201381%]). Among ART\u2010treated PLHIV diagnosed with cancer, MR and causes of death varied by cancer type, with mortality highest for liver and lung cancers. Deaths within 5\u2009years of NADM diagnoses were more likely to be from cancer than AIDS.<\/jats:p>","DOI":"10.1002\/ijc.32895","type":"journal-article","created":{"date-parts":[[2020,1,31]],"date-time":"2020-01-31T12:06:00Z","timestamp":1580472360000},"page":"3134-3146","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Cause\u2010specific mortality after diagnosis of cancer among HIV\u2010positive patients: A collaborative analysis of cohort studies"],"prefix":"10.1002","volume":"146","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3462-2898","authenticated-orcid":false,"given":"Adam","family":"Trickey","sequence":"first","affiliation":[{"name":"Population Health Sciences, University of Bristol  Bristol United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret T.","family":"May","sequence":"additional","affiliation":[{"name":"Population Health Sciences, University of Bristol  Bristol United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. 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