{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T19:12:00Z","timestamp":1792264320807,"version":"4.4.0"},"reference-count":46,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,8,7]],"date-time":"2020-08-07T00:00:00Z","timestamp":1596758400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100005895","name":"Fred Hutchinson Cancer Research Center","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005895","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009634","name":"Susan G. Komen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009634","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010586","name":"Haukeland Universitetssjukehus","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010586","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007048","name":"Mayo Foundation for Medical Education and Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007048","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001169","name":"Cancer Council Tasmania","doi-asserted-by":"publisher","award":["ID#457636"],"award-info":[{"award-number":["ID#457636"]}],"id":[{"id":"10.13039\/501100001169","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001169","name":"Cancer Council Tasmania","doi-asserted-by":"publisher","award":["ID#403031"],"award-info":[{"award-number":["ID#403031"]}],"id":[{"id":"10.13039\/501100001169","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["U19 CA148065\u201001"],"award-info":[{"award-number":["U19 CA148065\u201001"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001282","name":"Ovarian Cancer Research Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001282","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001006","name":"Breast Cancer Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001006","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["MOP\u201086727"],"award-info":[{"award-number":["MOP\u201086727"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001029","name":"Department of Defence, Australian Government","doi-asserted-by":"publisher","award":["W81XWH\u201010\u20101\u20100341"],"award-info":[{"award-number":["W81XWH\u201010\u20101\u20100341"]}],"id":[{"id":"10.13039\/501100001029","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000009","name":"Foundation for the National Institutes of Health","doi-asserted-by":"publisher","award":["CA128978"],"award-info":[{"award-number":["CA128978"]}],"id":[{"id":"10.13039\/100000009","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000289","name":"Cancer Research UK","doi-asserted-by":"publisher","award":["C490\/A10124"],"award-info":[{"award-number":["C490\/A10124"]}],"id":[{"id":"10.13039\/501100000289","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000289","name":"Cancer Research UK","doi-asserted-by":"publisher","award":["C8197\/A16565"],"award-info":[{"award-number":["C8197\/A16565"]}],"id":[{"id":"10.13039\/501100000289","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000289","name":"Cancer Research UK","doi-asserted-by":"publisher","award":["C5047\/A10692"],"award-info":[{"award-number":["C5047\/A10692"]}],"id":[{"id":"10.13039\/501100000289","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000289","name":"Cancer Research UK","doi-asserted-by":"publisher","award":["C5047\/A15007"],"award-info":[{"award-number":["C5047\/A15007"]}],"id":[{"id":"10.13039\/501100000289","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000289","name":"Cancer Research UK","doi-asserted-by":"publisher","award":["C5047\/A8384"],"award-info":[{"award-number":["C5047\/A8384"]}],"id":[{"id":"10.13039\/501100000289","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000289","name":"Cancer Research UK","doi-asserted-by":"publisher","award":["C1281\/A12014"],"award-info":[{"award-number":["C1281\/A12014"]}],"id":[{"id":"10.13039\/501100000289","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000289","name":"Cancer Research UK","doi-asserted-by":"publisher","award":["C12292\/A11174"],"award-info":[{"award-number":["C12292\/A11174"]}],"id":[{"id":"10.13039\/501100000289","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000289","name":"Cancer Research UK","doi-asserted-by":"publisher","award":["C1287\/A10710"],"award-info":[{"award-number":["C1287\/A10710"]}],"id":[{"id":"10.13039\/501100000289","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000289","name":"Cancer Research UK","doi-asserted-by":"publisher","award":["C1287\/A10118"],"award-info":[{"award-number":["C1287\/A10118"]}],"id":[{"id":"10.13039\/501100000289","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["ID#339435"],"award-info":[{"award-number":["ID#339435"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["G0000934"],"award-info":[{"award-number":["G0000934"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["ID#1031333"],"award-info":[{"award-number":["ID#1031333"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["ID#552402"],"award-info":[{"award-number":["ID#552402"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["ID#1109286"],"award-info":[{"award-number":["ID#1109286"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2021,1,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Blood lipids have been associated with the development of a range of cancers, including breast, lung and colorectal cancer. For endometrial cancer, observational studies have reported inconsistent associations between blood lipids and cancer risk. To reduce biases from unmeasured confounding, we performed a bidirectional, two\u2010sample Mendelian randomization analysis to investigate the relationship between levels of three blood lipids (low\u2010density lipoprotein [LDL] and high\u2010density lipoprotein [HDL] cholesterol, and triglycerides) and endometrial cancer risk. Genetic variants associated with each of these blood lipid levels (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u20095\u2009\u00d7\u200910\n                    <jats:sup>\u22128<\/jats:sup>\n                    ) were identified as instrumental variables, and assessed using genome\u2010wide association study data from the Endometrial Cancer Association Consortium (12\u2009906 cases and 108\u2009979 controls) and the Global Lipids Genetic Consortium (n = 188\u2009578). Mendelian randomization analyses found genetically raised LDL cholesterol levels to be associated with lower risks of endometrial cancer of all histologies combined, and of endometrioid and non\u2010endometrioid subtypes. Conversely, higher genetically predicted HDL cholesterol levels were associated with increased risk of non\u2010endometrioid endometrial cancer. After accounting for the potential confounding role of obesity (as measured by genetic variants associated with body mass index), the association between genetically predicted increased LDL cholesterol levels and lower endometrial cancer risk remained significant, especially for non\u2010endometrioid endometrial cancer. There was no evidence to support a role for triglycerides in endometrial cancer development. Our study supports a role for LDL and HDL cholesterol in the development of non\u2010endometrioid endometrial cancer. Further studies are required to understand the mechanisms underlying these findings.\n                  <\/jats:p>","DOI":"10.1002\/ijc.33206","type":"journal-article","created":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T09:04:31Z","timestamp":1594631071000},"page":"307-319","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":55,"title":["Mendelian randomization analyses suggest a role for cholesterol in the development of endometrial cancer"],"prefix":"10.1002","volume":"148","author":[{"given":"Pik\u2010Fang","family":"Kho","sequence":"first","affiliation":[{"name":"Department of Genetics and Computational Biology QIMR Berghofer Medical Research Institute  Brisbane Queensland Australia"},{"name":"School of Biomedical Science Queensland University of Technology  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederic","family":"Amant","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Division of Gynecologic Oncology University Hospitals KU Leuven, University of Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Annibali","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Division of Gynecologic Oncology University Hospitals KU Leuven, University of Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katie","family":"Ashton","sequence":"additional","affiliation":[{"name":"Hunter Medical Research Institute John Hunter Hospital  Newcastle New South Wales Australia"},{"name":"Centre for Information Based Medicine University of Newcastle  Callaghan New South Wales Australia"},{"name":"Discipline of Medical Genetics, School of Biomedical Sciences and Pharmacy, Faculty of Health University of Newcastle  Callaghan New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Attia","sequence":"additional","affiliation":[{"name":"Hunter Medical Research Institute John Hunter Hospital  Newcastle New South Wales Australia"},{"name":"Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health University of Newcastle  Callaghan New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul L.","family":"Auer","sequence":"additional","affiliation":[{"name":"Cancer Prevention Program Fred Hutchinson Cancer Research Center  Seattle Washington USA"},{"name":"Zilber School of Public Health University of Wisconsin\u2010Milwaukee  Milwaukee Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias W.","family":"Beckmann","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Comprehensive Cancer Center ER\u2010EMN University Hospital Erlangen, Friedrich\u2010Alexander\u2010University Erlangen\u2010Nuremberg  Erlangen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Black","sequence":"additional","affiliation":[{"name":"Division of Cancer Epidemiology and Genetics National Cancer Institute  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise","family":"Brinton","sequence":"additional","affiliation":[{"name":"Division of Cancer Epidemiology and Genetics National Cancer Institute  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2225-6675","authenticated-orcid":false,"given":"Daniel D.","family":"Buchanan","sequence":"additional","affiliation":[{"name":"Department of Clinical Pathology The University of Melbourne  Melbourne Victoria Australia"},{"name":"Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health The University of Melbourne  Melbourne Victoria Australia"},{"name":"Genomic Medicine and Family Cancer Clinic Royal Melbourne Hospital  Parkville Victoria Australia"},{"name":"University of Melbourne Centre for Cancer Research, Victorian Comprehensive Cancer Centre  Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen J.","family":"Chanock","sequence":"additional","affiliation":[{"name":"Department of Health and Human Services, Division of Cancer Epidemiology and Genetics National Cancer Institute, National Institutes of Health  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2267-8050","authenticated-orcid":false,"given":"Chu","family":"Chen","sequence":"additional","affiliation":[{"name":"Epidemiology Program Fred Hutchinson Cancer Research Center  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maxine M.","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Harvard T.H. Chan School of Public Health  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy H. T.","family":"Cheng","sequence":"additional","affiliation":[{"name":"Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre University of Oxford  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda S.","family":"Cook","sequence":"additional","affiliation":[{"name":"University of New Mexico Health Sciences Center  Albuquerque New Mexico USA"},{"name":"Department of Cancer Epidemiology and Prevention Research Alberta Health Services  Calgary Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Crous\u2010Bous","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Harvard T.H. Chan School of Public Health  Boston Massachusetts USA"},{"name":"Channing Division of Network Medicine, Department of Medicine Brigham and Women's Hospital and Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamila","family":"Czene","sequence":"additional","affiliation":[{"name":"Department of Medical Epidemiology and Biostatistics Karolinska Institutet  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7185-7402","authenticated-orcid":false,"given":"Immaculata","family":"De Vivo","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Harvard T.H. Chan School of Public Health  Boston Massachusetts USA"},{"name":"Channing Division of Network Medicine, Department of Medicine Brigham and Women's Hospital and Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joe","family":"Dennis","sequence":"additional","affiliation":[{"name":"Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care University of Cambridge  Cambridge UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9458-0282","authenticated-orcid":false,"given":"Thilo","family":"D\u00f6rk","sequence":"additional","affiliation":[{"name":"Gynaecology Research Unit Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean C.","family":"Dowdy","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Division of Gynecologic Oncology Mayo Clinic  Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison M.","family":"Dunning","sequence":"additional","affiliation":[{"name":"Centre for Cancer Genetic Epidemiology, Department of Oncology University of Cambridge  Cambridge UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"D\u00fcrst","sequence":"additional","affiliation":[{"name":"Department of Gynaecology Jena University Hospital \u2010 Friedrich Schiller University  Jena Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas F.","family":"Easton","sequence":"additional","affiliation":[{"name":"Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care University of Cambridge  Cambridge UK"},{"name":"Centre for Cancer Genetic Epidemiology, Department of Oncology University of Cambridge  Cambridge UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arif B.","family":"Ekici","sequence":"additional","affiliation":[{"name":"Institute of Human Genetics, University Hospital Erlangen, Friedrich\u2010Alexander University Erlangen\u2010Nuremberg, Comprehensive Cancer Center Erlangen\u2010EMN  Erlangen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4885-8471","authenticated-orcid":false,"given":"Peter A.","family":"Fasching","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Comprehensive Cancer Center ER\u2010EMN University Hospital Erlangen, Friedrich\u2010Alexander\u2010University Erlangen\u2010Nuremberg  Erlangen Germany"},{"name":"David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology University of California at Los Angeles  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brooke L.","family":"Fridley","sequence":"additional","affiliation":[{"name":"Department of Biostatistics Kansas University Medical Center  Kansas City Kansas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4783-1966","authenticated-orcid":false,"given":"Christine M.","family":"Friedenreich","sequence":"additional","affiliation":[{"name":"Department of Cancer Epidemiology and Prevention Research Alberta Health Services  Calgary Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Montserrat","family":"Garc\u00eda\u2010Closas","sequence":"additional","affiliation":[{"name":"Department of Health and Human Services, Division of Cancer Epidemiology and Genetics National Cancer Institute, National Institutes of Health  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6429-4007","authenticated-orcid":false,"given":"Mia M.","family":"Gaudet","sequence":"additional","affiliation":[{"name":"Behavioral and Epidemiology Research Group American Cancer Society  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graham G.","family":"Giles","sequence":"additional","affiliation":[{"name":"Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health The University of Melbourne  Melbourne Victoria Australia"},{"name":"Cancer Epidemiology Division Cancer Council Victoria  Melbourne Victoria Australia"},{"name":"Precision Medicine, School of Clinical Sciences at Monash Health Monash University  Clayton Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9094-8326","authenticated-orcid":false,"given":"Ellen L.","family":"Goode","sequence":"additional","affiliation":[{"name":"Department of Health Science Research, Division of Epidemiology Mayo Clinic  Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maggie","family":"Gorman","sequence":"additional","affiliation":[{"name":"Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre University of Oxford  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher A.","family":"Haiman","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, Keck School of Medicine University of Southern California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per","family":"Hall","sequence":"additional","affiliation":[{"name":"Department of Medical Epidemiology and Biostatistics Karolinska Institutet  Stockholm Sweden"},{"name":"Department of Oncology S\u00f6dersjukhuset  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan E.","family":"Hankinson","sequence":"additional","affiliation":[{"name":"Channing Division of Network Medicine, Department of Medicine Brigham and Women's Hospital and Harvard Medical School  Boston Massachusetts USA"},{"name":"Department of Biostatistics &amp; Epidemiology University of Massachusetts, Amherst  Amherst Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Hein","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Comprehensive Cancer Center ER\u2010EMN University Hospital Erlangen, Friedrich\u2010Alexander\u2010University Erlangen\u2010Nuremberg  Erlangen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Hillemanns","sequence":"additional","affiliation":[{"name":"Gynaecology Research Unit Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shirley","family":"Hodgson","sequence":"additional","affiliation":[{"name":"Department of Clinical Genetics St George's, University of London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erling A.","family":"Hoivik","sequence":"additional","affiliation":[{"name":"Centre for Cancer Biomarkers CCBIO, Department of Clinical Science University of Bergen  Bergen Norway"},{"name":"Department of Obstetrics and Gynecology Haukeland University Hospital  Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth G.","family":"Holliday","sequence":"additional","affiliation":[{"name":"Hunter Medical Research Institute John Hunter Hospital  Newcastle New South Wales Australia"},{"name":"Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health University of Newcastle  Callaghan New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Hunter","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Harvard T.H. Chan School of Public Health  Boston Massachusetts USA"},{"name":"Program in Genetic Epidemiology and Statistical Genetics Harvard T.H. Chan School of Public Health  Boston Massachusetts USA"},{"name":"Nuffield Department of Population Health University of Oxford  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Jones","sequence":"additional","affiliation":[{"name":"Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre University of Oxford  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Kraft","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Harvard T.H. Chan School of Public Health  Boston Massachusetts USA"},{"name":"Program in Genetic Epidemiology and Statistical Genetics Harvard T.H. Chan School of Public Health  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camilla","family":"Krakstad","sequence":"additional","affiliation":[{"name":"Centre for Cancer Biomarkers CCBIO, Department of Clinical Science University of Bergen  Bergen Norway"},{"name":"Department of Obstetrics and Gynecology Haukeland University Hospital  Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diether","family":"Lambrechts","sequence":"additional","affiliation":[{"name":"VIB Center for Cancer Biology  Leuven Belgium"},{"name":"Laboratory for Translational Genetics, Department of Human Genetics University of Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loic","family":"Le Marchand","sequence":"additional","affiliation":[{"name":"Epidemiology Program University of Hawaii Cancer Center  Honolulu Hawaii USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolin","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics Memorial Sloan\u2010Kettering Cancer Center  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annika","family":"Lindblom","sequence":"additional","affiliation":[{"name":"Department of Molecular Medicine and Surgery Karolinska Institutet  Stockholm Sweden"},{"name":"Department of Clinical Genetics Karolinska University Hospital  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jolanta","family":"Lissowska","sequence":"additional","affiliation":[{"name":"Department of Cancer Epidemiology and Prevention, M. Sklodowska\u2010Curie Cancer Center Oncology Institute  Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jirong","family":"Long","sequence":"additional","affiliation":[{"name":"Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt\u2010Ingram Cancer Center Vanderbilt University School of Medicine  Nashville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9871-0809","authenticated-orcid":false,"given":"Lingeng","family":"Lu","sequence":"additional","affiliation":[{"name":"Chronic Disease Epidemiology Yale School of Medicine  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony M.","family":"Magliocco","sequence":"additional","affiliation":[{"name":"Department of Anatomic Pathology Moffitt Cancer Center &amp; Research Institute  Tampa Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynn","family":"Martin","sequence":"additional","affiliation":[{"name":"Institute of Cancer and Genomic Sciences, University of Birmingham  Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"McEvoy","sequence":"additional","affiliation":[{"name":"Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health University of Newcastle  Callaghan New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger L.","family":"Milne","sequence":"additional","affiliation":[{"name":"Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health The University of Melbourne  Melbourne Victoria Australia"},{"name":"Cancer Epidemiology Division Cancer Council Victoria  Melbourne Victoria Australia"},{"name":"Precision Medicine, School of Clinical Sciences at Monash Health Monash University  Clayton Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriam","family":"Mints","sequence":"additional","affiliation":[{"name":"Department of Women's and Children's Health Karolinska Institutet  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rami","family":"Nassir","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Medicine University of California Davis  Davis California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geoffrey","family":"Otton","sequence":"additional","affiliation":[{"name":"School of Medicine and Public Health University of Newcastle  Callaghan New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Palles","sequence":"additional","affiliation":[{"name":"Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre University of Oxford  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loreall","family":"Pooler","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, Keck School of Medicine University of Southern California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tony","family":"Proietto","sequence":"additional","affiliation":[{"name":"School of Medicine and Public Health University of Newcastle  Callaghan New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy R.","family":"Rebbeck","sequence":"additional","affiliation":[{"name":"Harvard T.H. Chan School of Public Health  Boston Massachusetts USA"},{"name":"Dana\u2010Farber Cancer Institute  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan P.","family":"Renner","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics University Hospital Erlangen, Friedrich\u2010Alexander University Erlangen\u2010Nuremberg, Comprehensive Cancer Center Erlangen\u2010EMN  Erlangen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harvey A.","family":"Risch","sequence":"additional","affiliation":[{"name":"Chronic Disease Epidemiology Yale School of Medicine  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"R\u00fcbner","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics University Hospital Erlangen, Friedrich\u2010Alexander University Erlangen\u2010Nuremberg, Comprehensive Cancer Center Erlangen\u2010EMN  Erlangen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingo","family":"Runnebaum","sequence":"additional","affiliation":[{"name":"Department of Gynaecology Jena University Hospital \u2010 Friedrich Schiller University  Jena Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8008-5096","authenticated-orcid":false,"given":"Carlotta","family":"Sacerdote","sequence":"additional","affiliation":[{"name":"Center for Cancer Prevention (CPO\u2010Peimonte)  Turin Italy"},{"name":"Human Genetics Foundation (HuGeF)  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gloria E.","family":"Sarto","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, School of Medicine and Public Health University of Wisconsin  Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fredrick","family":"Schumacher","sequence":"additional","affiliation":[{"name":"Department of Population and Quantitative Health Sciences Case Western Reserve University  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodney J.","family":"Scott","sequence":"additional","affiliation":[{"name":"Hunter Medical Research Institute John Hunter Hospital  Newcastle New South Wales Australia"},{"name":"Discipline of Medical Genetics, School of Biomedical Sciences and Pharmacy, Faculty of Health University of Newcastle  Callaghan New South Wales Australia"},{"name":"Division of Molecular Medicine, Pathology North John Hunter Hospital  Newcastle New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V. Wendy","family":"Setiawan","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, Keck School of Medicine University of Southern California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitul","family":"Shah","sequence":"additional","affiliation":[{"name":"Centre for Cancer Genetic Epidemiology, Department of Oncology University of Cambridge  Cambridge UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Sheng","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, Keck School of Medicine University of Southern California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0711-8314","authenticated-orcid":false,"given":"Xiao\u2010Ou","family":"Shu","sequence":"additional","affiliation":[{"name":"Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt\u2010Ingram Cancer Center Vanderbilt University School of Medicine  Nashville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa C.","family":"Southey","sequence":"additional","affiliation":[{"name":"Department of Clinical Pathology The University of Melbourne  Melbourne Victoria Australia"},{"name":"Cancer Epidemiology Division Cancer Council Victoria  Melbourne Victoria Australia"},{"name":"Precision Medicine, School of Clinical Sciences at Monash Health Monash University  Clayton Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma","family":"Tham","sequence":"additional","affiliation":[{"name":"Department of Molecular Medicine and Surgery Karolinska Institutet  Stockholm Sweden"},{"name":"Clinical Genetics Karolinska Institutet  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Tomlinson","sequence":"additional","affiliation":[{"name":"Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre University of Oxford  Oxford UK"},{"name":"Institute of Cancer and Genomic Sciences, University of Birmingham  Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jone","family":"Trovik","sequence":"additional","affiliation":[{"name":"Centre for Cancer Biomarkers CCBIO, Department of Clinical Science University of Bergen  Bergen Norway"},{"name":"Department of Obstetrics and Gynecology Haukeland University Hospital  Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constance","family":"Turman","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Harvard T.H. Chan School of Public Health  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan P.","family":"Tyrer","sequence":"additional","affiliation":[{"name":"Centre for Cancer Genetic Epidemiology, Department of Oncology University of Cambridge  Cambridge UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Van Den Berg","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, Keck School of Medicine University of Southern California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7556-3869","authenticated-orcid":false,"given":"Zhaoming","family":"Wang","sequence":"additional","affiliation":[{"name":"Division of Cancer Epidemiology and Genetics National Cancer Institute  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1251-0836","authenticated-orcid":false,"given":"Nicolas","family":"Wentzensen","sequence":"additional","affiliation":[{"name":"Division of Cancer Epidemiology and Genetics National Cancer Institute  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucy","family":"Xia","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, Keck School of Medicine University of Southern California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3840-9915","authenticated-orcid":false,"given":"Yong\u2010Bing","family":"Xiang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oncogene and Related Genes &amp; Department of Epidemiology Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah P.","family":"Yang","sequence":"additional","affiliation":[{"name":"Division of Cancer Epidemiology and Genetics National Cancer Institute  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3950-4815","authenticated-orcid":false,"given":"Herbert","family":"Yu","sequence":"additional","affiliation":[{"name":"Epidemiology Program University of Hawaii Cancer Center  Honolulu Hawaii USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Zheng","sequence":"additional","affiliation":[{"name":"Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt\u2010Ingram Cancer Center Vanderbilt University School of Medicine  Nashville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Penelope M.","family":"Webb","sequence":"additional","affiliation":[{"name":"Population Health Department QIMR Berghofer Medical Research Institute  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah J.","family":"Thompson","sequence":"additional","affiliation":[{"name":"Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care University of Cambridge  Cambridge UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1337-7897","authenticated-orcid":false,"given":"Amanda B.","family":"Spurdle","sequence":"additional","affiliation":[{"name":"Department of Genetics and Computational Biology QIMR Berghofer Medical Research Institute  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dylan M.","family":"Glubb","sequence":"additional","affiliation":[{"name":"Department of Genetics and Computational Biology QIMR Berghofer Medical Research Institute  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5436-3232","authenticated-orcid":false,"given":"Tracy A.","family":"O'Mara","sequence":"additional","affiliation":[{"name":"Department of Genetics and Computational Biology QIMR Berghofer Medical Research Institute  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,8,7]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21492"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2017.08.011"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.2217\/fon.14.142"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)00130-0"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djv178"},{"key":"e_1_2_10_7_1","first-page":"ED000095","article-title":"The emerging epidemic of endometrial cancer: time to take action","author":"Crosbie E","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdv142"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2004-0395"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2019.05.037"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20160935"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2017.01.017"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2016.02.017"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hyt125"},{"key":"e_1_2_10_15_1","first-page":"575","article-title":"Endometrial cancer risk in relation to serum lipids and lipoprotein levels","volume":"3","author":"Swanson CA","year":"1994","journal-title":"Cancer Epidemiol Biomark Prev"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2009.12.029"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-11-0715"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.24285"},{"key":"e_1_2_10_19_1","first-page":"122","article-title":"Lipid profiles and the risk of endometrial cancer in the Swedish AMORIS study","volume":"3","author":"Seth D","year":"2012","journal-title":"Int J Mol Epidemiol Genet"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwq006"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-017-0991-y"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1677\/ERC-07-0132"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.30560"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-14-0923"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.17219"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.2797"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-05427-7"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.3562"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-02317-2"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.34408"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddy271"},{"key":"e_1_2_10_32_1","volume-title":"Endotexted","author":"Feingold KR","year":"2000"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2013.12.014"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-16-0147"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc18-0372"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2012.48.2596"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kws200"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-06467-9"},{"key":"e_1_2_10_39_1","article-title":"Assessing a causal relationship between circulating lipids and breast cancer risk: Mendelian randomization study","author":"Johnson KE","year":"2019","journal-title":"bioRxiv"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyz242"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0177875"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2017.09.019"},{"key":"e_1_2_10_43_1","first-page":"1240","article-title":"Cell death induced by peroxidized low\u2010density lipoprotein: endopepsis","volume":"54","author":"Fossel ET","year":"1994","journal-title":"Cancer Res"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10456-013-9340-2"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.765032"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature02924"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-11-0817"}],"container-title":["International Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fijc.33206","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.33206","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ijc.33206","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.33206","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T02:37:49Z","timestamp":1693795069000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ijc.33206"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,7]]},"references-count":46,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,1,15]]}},"alternative-id":["10.1002\/ijc.33206"],"URL":"https:\/\/doi.org\/10.1002\/ijc.33206","archive":["Portico"],"relation":{},"ISSN":["0020-7136","1097-0215"],"issn-type":[{"value":"0020-7136","type":"print"},{"value":"1097-0215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,7]]},"assertion":[{"value":"2019-12-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}