{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T22:36:30Z","timestamp":1782513390270,"version":"3.54.5"},"reference-count":33,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2021,2,17]],"date-time":"2021-02-17T00:00:00Z","timestamp":1613520000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["NIH\/NHLBI\u2010CSB\u2010WH\u20102016\u201001\u2010CM"],"award-info":[{"award-number":["NIH\/NHLBI\u2010CSB\u2010WH\u20102016\u201001\u2010CM"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["UM1\u2010CA173642\u201005"],"award-info":[{"award-number":["UM1\u2010CA173642\u201005"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HHSN268201600004C"],"award-info":[{"award-number":["HHSN268201600004C"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HHSN268201600003C"],"award-info":[{"award-number":["HHSN268201600003C"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HHSN268201600002C"],"award-info":[{"award-number":["HHSN268201600002C"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HHSN268201600001C"],"award-info":[{"award-number":["HHSN268201600001C"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HHSN268201600018C"],"award-info":[{"award-number":["HHSN268201600018C"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"The National Cancer Institute","doi-asserted-by":"publisher","award":["U01\u2010CA202979"],"award-info":[{"award-number":["U01\u2010CA202979"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"The National Cancer Institute","doi-asserted-by":"publisher","award":["P30\u2010CA014089"],"award-info":[{"award-number":["P30\u2010CA014089"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"The National Cancer Institute","doi-asserted-by":"publisher","award":["P30\u2010CA68485"],"award-info":[{"award-number":["P30\u2010CA68485"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"The National Cancer Institute","doi-asserted-by":"publisher","award":["R01\u2010CA092447"],"award-info":[{"award-number":["R01\u2010CA092447"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"The National Cancer Institute","doi-asserted-by":"publisher","award":["R01\u2010CA076016"],"award-info":[{"award-number":["R01\u2010CA076016"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"The National Cancer Institute","doi-asserted-by":"publisher","award":["R01\u2010CA58598"],"award-info":[{"award-number":["R01\u2010CA58598"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"The National Cancer Institute","doi-asserted-by":"publisher","award":["R01\u2010CA17054"],"award-info":[{"award-number":["R01\u2010CA17054"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"The National Cancer Institute","doi-asserted-by":"publisher","award":["R01\u2010CA142081"],"award-info":[{"award-number":["R01\u2010CA142081"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"The National Cancer Institute","doi-asserted-by":"publisher","award":["R01\u2010CA61093"],"award-info":[{"award-number":["R01\u2010CA61093"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"The National Cancer Institute","doi-asserted-by":"publisher","award":["U01\u2010CA164974"],"award-info":[{"award-number":["U01\u2010CA164974"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"The National Cancer Institute","doi-asserted-by":"publisher","award":["UM1\u2010CA164974"],"award-info":[{"award-number":["UM1\u2010CA164974"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"The National Cancer Institute","doi-asserted-by":"publisher","award":["R01\u2010CA058420"],"award-info":[{"award-number":["R01\u2010CA058420"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"The National Cancer Institute","doi-asserted-by":"publisher","award":["K01\u2010CA212056"],"award-info":[{"award-number":["K01\u2010CA212056"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"The National Cancer Institute","doi-asserted-by":"publisher","award":["R01\u2010CA207260"],"award-info":[{"award-number":["R01\u2010CA207260"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2021,6,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Family history (FH) of ovarian cancer and breast cancer are well\u2010established risk factors for ovarian cancer, but few studies have examined this association in African American (AA) and white women by histotype. We assessed first\u2010 and second\u2010degree FH of ovarian and breast cancer and risk of epithelial ovarian cancer in the Ovarian Cancer in Women of African Ancestry Consortium. Analyses included 1052 AA cases, 2328 AA controls, 2380 white cases and 3982 white controls. Race\u2010specific odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using multilevel logistic regression with adjustment for covariates. Analyses were stratified by histotype (high\u2010grade serous vs others). First\u2010degree FH of ovarian cancer was associated with high\u2010grade serous carcinoma in AA (OR = 2.32, 95% CI: 1.50, 3.59) and white women (OR = 2.48, 95% CI: 1.82, 3.38). First\u2010degree FH of breast cancer increased risk irrespective of histotype in AAs, but with high\u2010grade serous carcinoma only in white women. Associations with second\u2010degree FH of ovarian cancer were observed for overall ovarian cancer in white women and with high\u2010grade serous carcinoma in both groups. First\u2010degree FH of ovarian cancer and of breast cancer, and second\u2010degree FH of ovarian cancer is strongly associated with high\u2010grade serous ovarian carcinoma in AA and white women. The association of FH of breast cancer with high\u2010grade serous ovarian carcinoma is similar in white women and AA women, but may differ for other histotypes.<\/jats:p>","DOI":"10.1002\/ijc.33493","type":"journal-article","created":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T06:31:13Z","timestamp":1612161073000},"page":"2964-2973","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["First\u2010 and second\u2010degree family history of ovarian and breast cancer in relation to risk of invasive ovarian cancer in African American and white women"],"prefix":"10.1002","volume":"148","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3205-2078","authenticated-orcid":false,"given":"Traci N.","family":"Bethea","sequence":"first","affiliation":[{"name":"Office of Minority Health and Health Disparities Research Georgetown Lombardi Comprehensive Cancer Center, Georgetown University Medical Campus  Washington DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1255-7714","authenticated-orcid":false,"given":"Heather M.","family":"Ochs\u2010Balcom","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Environmental Health School of Public Health and Health Professions, University at Buffalo, The State University of New York  Buffalo New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisa V.","family":"Bandera","sequence":"additional","affiliation":[{"name":"Cancer Epidemiology and Health Outcomes Rutgers Cancer Institute of New Jersey  New Brunswick New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicia","family":"Beeghly\u2010Fadiel","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Epidemiology Vanderbilt University Medical Center  Nashville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabian","family":"Camacho","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences University of Virginia  Charlottesville Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deanna","family":"Chyn","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences University of Virginia  Charlottesville Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily K.","family":"Cloyd","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences University of Virginia  Charlottesville Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holly R.","family":"Harris","sequence":"additional","affiliation":[{"name":"Program in Epidemiology, Division of Public Health Sciences Fred Hutchinson Cancer Research Center  Seattle Washington USA"},{"name":"Department of Epidemiology University of Washington  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1402-3989","authenticated-orcid":false,"given":"Charlotte E.","family":"Joslin","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences University of Illinois at Chicago School of Medicine  Chicago Illinois USA"},{"name":"Division of Epidemiology and Biostatistics University of Illinois at Chicago School of Public Health  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evan","family":"Myers","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Duke University Medical Center  Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia G.","family":"Moorman","sequence":"additional","affiliation":[{"name":"Department of Family Medicine and Community Health Duke University Medical Center  Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6620-8600","authenticated-orcid":false,"given":"Lauren C.","family":"Peres","sequence":"additional","affiliation":[{"name":"Department of Cancer Epidemiology H. Lee Moffitt Cancer Center and Research Institute  Tampa Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Will","family":"Rosenow","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences University of Virginia  Charlottesville Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronica W.","family":"Setiawan","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center  Los Angeles, California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna H.","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center  Los Angeles, California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynn","family":"Rosenberg","sequence":"additional","affiliation":[{"name":"Slone Epidemiology Center at Boston University  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joellen M.","family":"Schildkraut","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Rollins School of Public Health, Emory University  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,2,17]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/bs.acr.2020.01.002"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-016-0806-6"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2017.10.001"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/CEJ.0000000000000217"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1998.tb10148.x"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyx252"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-019-01199-7"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-14-688"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2015.00008"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.24091"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwp176"},{"issue":"2","key":"e_1_2_10_13_1","first-page":"56","article-title":"The Black Women's Health Study: a follow\u2010up study for causes and preventions of illness","volume":"50","author":"Rosenberg L","year":"1995","journal-title":"J Am Med Womens Assoc"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a010213"},{"issue":"7","key":"e_1_2_10_15_1","first-page":"972","article-title":"Southern Community Cohort Study: establishing a cohort to investigate health disparities","volume":"97","author":"Signorello LB","year":"2005","journal-title":"J Natl Med Assoc"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1047-2797(03)00042-5"},{"key":"e_1_2_10_17_1","unstructured":"World Health Organization.International Classification of Diseases for Oncology;2000."},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djy071"},{"issue":"3","key":"e_1_2_10_19_1","first-page":"33","article-title":"Ovarian carcinoma: recent developments of tumour histological subtype","volume":"3","author":"Clarke BA","year":"2011","journal-title":"Can J Pathol"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/MLR.0000000000000696"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwt245"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13142-016-0386-8"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/jrsm.1164"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a114174"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2016.66.8178"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-8049(99)00313-5"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-15-0023"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.18280"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2014.00019"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-1029-3"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-19-0444"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a009259"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-007-9108-3"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-29888-4"}],"container-title":["International Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.33493","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ijc.33493","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.33493","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T04:58:42Z","timestamp":1693544322000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ijc.33493"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,17]]},"references-count":33,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2021,6,15]]}},"alternative-id":["10.1002\/ijc.33493"],"URL":"https:\/\/doi.org\/10.1002\/ijc.33493","archive":["Portico"],"relation":{},"ISSN":["0020-7136","1097-0215"],"issn-type":[{"value":"0020-7136","type":"print"},{"value":"1097-0215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,17]]},"assertion":[{"value":"2020-11-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-02-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}