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To investigate if there are any actively transcribed HPV infections in these tumors, we identified all skin cancers diagnosed after solid organ transplantation in Sweden during 1964\u20102011 (n\u00a0=\u00a07614 NMSCs) and requested the diagnostic tumor blocks from the corresponding pathology archives. For the present study, we selected diagnostic specimens from 345 NMSC and performed whole genome transcriptome analysis using NovaSeq (Illumina), in comparison with three cervical cancers. Although we obtained an abundance of high\u2010quality paired reads per sample (median of 35 million reads), only 15 NMSC specimens contained HPV transcription. Three specimens had transcription of oncogenic anogenital HPVs (HPV16 and 56), six tumors had transcription of HPVs from the beta\u20102 species (three HPV38, two with HPV23 and one with HPV107) and then there was one observation each of transcription of HPVs 3, 26, 57, 147, 158, 168 and of two nonestablished HPV types belonging to the gamma genus. In conclusion, transcription of specific HPV types can be found in NMSC among the immunosuppressed, but this is not common.<\/jats:p>","DOI":"10.1002\/ijc.33683","type":"journal-article","created":{"date-parts":[[2021,5,15]],"date-time":"2021-05-15T00:14:45Z","timestamp":1621037685000},"page":"1341-1347","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Transcription of human papillomaviruses in\n                    <scp>nonmelanoma<\/scp>\n                    skin cancers of the immunosuppressed"],"prefix":"10.1002","volume":"149","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2498-5206","authenticated-orcid":false,"given":"Laila Sara","family":"Arroyo M\u00fchr","sequence":"first","affiliation":[{"name":"Department of Laboratory Medicine Karolinska Institutet  Stockholm 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