{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T11:30:37Z","timestamp":1774438237767,"version":"3.50.1"},"reference-count":34,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2021,6,19]],"date-time":"2021-06-19T00:00:00Z","timestamp":1624060800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["U01AI069919"],"award-info":[{"award-number":["U01AI069919"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2021,10,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Non\u2010Hodgkin lymphomas (NHL) are underestimated causes of cancer in West Africa where chronic viral hepatitis and HIV are endemic. While the association with HIV infection has already been characterized, limited information is available on the association between chronic viral hepatitis and NHL in sub\u2010Saharan Africa. A case\u2010control study was conducted in referral hospitals of Abidjan (Cote d'Ivoire) and Dakar (Senegal). Cases of NHL were matched with controls on age, gender and participating site. The diagnosis of NHL relied on local pathological examination completed with immunohistochemistry. HIV, HBV and HCV serology tests were systematically performed. A conditional logistic regression model estimated the associations by the Odds Ratio (OR) with their 95% confidence interval (CI). A total of 117 NHL cases (Abidjan n\u00a0=\u00a097, Dakar n\u00a0=\u00a020) and their 234 matched controls were enrolled. Cases were predominantly men (68.4%) and had a median age of 50\u2009years (IQR 37\u201057). While Diffuse Large B\u2010cell lymphoma were the most reported morphological type (n\u00a0=\u00a035) among mature B\u2010cell NHL, the proportion mature T\u2010cell NHL (30%) was high. The prevalence figures of HBV, HCV and HIV infection were 12.8%, 7.7% and 14.5%, respectively among cases of NHL. In multivariate analysis, HBV, HCV and HIV were independently associated with NHL with OR of 2.23 (CI 1.05\u20104.75), 4.82 (CI 1.52\u201015.29) and 3.32 (CI 1.54\u20107.16), respectively. Chronic viral hepatitis B and C were significantly associated with NHL in West Africa. Timely preventive measures against HBV infection and access to curative anti\u2010HCV treatment might prevent a significant number of NHL.<\/jats:p>","DOI":"10.1002\/ijc.33709","type":"journal-article","created":{"date-parts":[[2021,6,14]],"date-time":"2021-06-14T09:30:46Z","timestamp":1623663046000},"page":"1536-1543","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Chronic viral hepatitis, <scp>HIV<\/scp> infection and <scp>Non\u2010Hodgkin<\/scp> lymphomas in West Africa, a case\u2010control study"],"prefix":"10.1002","volume":"149","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3426-9492","authenticated-orcid":false,"given":"Antoine","family":"Jaquet","sequence":"first","affiliation":[{"name":"University of Bordeaux Inserm, French National Research Institute for Sustainable Development (IRD)  Bordeaux France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon P.","family":"Boni","sequence":"additional","affiliation":[{"name":"Programme National de Lutte Contre le Cancer (PNLCa)  Abidjan C\u00f4te d'Ivoire"},{"name":"Programme PACCI\/Site ANRS Abidjan  Abidjan C\u00f4te d'Ivoire"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kouakou","family":"Boidy","sequence":"additional","affiliation":[{"name":"Service d'h\u00e9matologie Centre Hospitalier Universitaire de Yopougon  Abidjan C\u00f4te d'Ivoire"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judica\u00ebl","family":"Tine","sequence":"additional","affiliation":[{"name":"Service des Maladies Infectieuses et Tropicales Centre Hospitalier National Universitaire de Fann  Dakar Senegal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boris","family":"Tchounga","sequence":"additional","affiliation":[{"name":"Programme PACCI\/Site ANRS Abidjan  Abidjan C\u00f4te d'Ivoire"},{"name":"Elizabeth Glaser Pediatric AIDS Foundation  Yaound\u00e9 Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sokhna A.","family":"Tour\u00e9","sequence":"additional","affiliation":[{"name":"Service d'h\u00e9matologie Centre National de Transfusion Sanguine  Dakar Senegal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean\u2010Jacques","family":"Koffi","sequence":"additional","affiliation":[{"name":"Programme PACCI\/Site ANRS Abidjan  Abidjan C\u00f4te d'Ivoire"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cherif","family":"Dial","sequence":"additional","affiliation":[{"name":"Service Anatomopathologie H\u00f4pital de Grand Yoff  Dakar Senegal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alain","family":"Monnereau","sequence":"additional","affiliation":[{"name":"University of Bordeaux Inserm, French National Research Institute for Sustainable Development (IRD)  Bordeaux France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isidore","family":"Diomande","sequence":"additional","affiliation":[{"name":"Service Anatomopathologie Centre Hospitalier Universitaire Cocody  Abidjan C\u00f4te d'Ivoire"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aristophane","family":"Tanon","sequence":"additional","affiliation":[{"name":"Service des Maladies Infectieuses et Tropicales Centre Hospitalier Universitaire de Treichville  Abidjan C\u00f4te d'Ivoire"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moussa","family":"Seydi","sequence":"additional","affiliation":[{"name":"Service des Maladies Infectieuses et Tropicales Centre Hospitalier National Universitaire de Fann  Dakar Senegal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran\u00e7ois","family":"Dabis","sequence":"additional","affiliation":[{"name":"University of Bordeaux Inserm, French National Research Institute for Sustainable Development (IRD)  Bordeaux France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saliou","family":"Diop","sequence":"additional","affiliation":[{"name":"Service d'h\u00e9matologie Centre National de Transfusion Sanguine  Dakar Senegal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gustave","family":"Koffi","sequence":"additional","affiliation":[{"name":"Service d'h\u00e9matologie Centre Hospitalier Universitaire de Yopougon  Abidjan C\u00f4te d'Ivoire"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"The IeDEA West Africa Collaboration","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,6,19]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1200\/JGO.2015.000299"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21492"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000000620"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.28661"},{"key":"e_1_2_11_6_1","unstructured":"IARC Working Group on the Evaluation of Carcinogenic Risks to Humans.IARC Monographs on the Evaluation of Carcinogenic Risks to Humans Biological Agents. Vol 100B. Lyon: International Agency for Research on Cancer 2012http:\/\/monographs.iarc.fr\/ENG\/Monographs\/vol100B\/. Accessed January 12 2020."},{"key":"e_1_2_11_7_1","first-page":"1","article-title":"1993 revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults","volume":"41","author":"Anonymous","year":"1992","journal-title":"MMWR Recomm Rep"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13027-019-0228-7"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canep.2015.09.002"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3018(18)30360-6"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3018(17)30125-X"},{"key":"e_1_2_11_12_1","unstructured":"IARC List of Classifications Agents classified by the IARC Monographs. Vols. 1\u2013128. Lyon: International Agency for Research on Cancer 2020.https:\/\/monographs.iarc.fr\/wp-content\/uploads\/2019\/07\/Classifications_by_cancer_site.pdf. Accessed August 12 2020."},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvh.12892"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-06-289561"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/07357900600815232"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.leukres.2013.06.007"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-06-275818"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.33027"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-019-5718-x"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.2471\/BLT.18.208603"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(15)00006-7"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-017-2775-0"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa1046"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.28894"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-018-0265-3"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/aqw118"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.2631"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0150445"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.13885"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2016.148809"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2017.01425"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/tmi.13305"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.15234"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)61412-X"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.31537"}],"container-title":["International Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.33709","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ijc.33709","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.33709","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,16]],"date-time":"2023-08-16T23:20:31Z","timestamp":1692228031000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ijc.33709"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,19]]},"references-count":34,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,10,15]]}},"alternative-id":["10.1002\/ijc.33709"],"URL":"https:\/\/doi.org\/10.1002\/ijc.33709","archive":["Portico"],"relation":{},"ISSN":["0020-7136","1097-0215"],"issn-type":[{"value":"0020-7136","type":"print"},{"value":"1097-0215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,19]]},"assertion":[{"value":"2021-04-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-05-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-06-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}