{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:11:28Z","timestamp":1772118688387,"version":"3.50.1"},"reference-count":44,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,11,3]],"date-time":"2021-11-03T00:00:00Z","timestamp":1635897600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["CM20\/00174"],"award-info":[{"award-number":["CM20\/00174"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"publisher","award":["Investment ID INV\u2010016201"],"award-info":[{"award-number":["Investment ID INV\u2010016201"]}],"id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100013322","name":"European Federation of Pharmaceutical Industries and Associations","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The relationship between cancer and coronavirus disease 2019 (COVID\u201019) infection and severity remains poorly understood. We conducted a population\u2010based cohort study between 1 March and 6 May 2020 describing the associations between cancer and risk of COVID\u201019 diagnosis, hospitalisation and COVID\u201019\u2010related death. Data were obtained from the Information System for Research in Primary Care (SIDIAP) database, including primary care electronic health records from ~80% of the population in Catalonia, Spain. Cancer was defined as any primary invasive malignancy excluding non\u2010melanoma skin cancer. We estimated adjusted hazard ratios (aHRs) for the risk of COVID\u201019 (outpatient) clinical diagnosis, hospitalisation (with or without a prior COVID\u201019 diagnosis) and COVID\u201019\u2010related death using Cox proportional hazard regressions. Models were estimated for the overall cancer population and by years since cancer diagnosis (&lt;1\u00a0year, 1\u20105\u2009years and \u22655\u2009years), sex, age and cancer type; and adjusted for age, sex, smoking status, deprivation and comorbidities. We included 4\u2009618\u2009377 adults, of which 260\u2009667 (5.6%) had a history of cancer. A total of 98\u2009951 individuals (5.5% with cancer) were diagnosed, and 6355 (16.4% with cancer) were directly hospitalised with COVID\u201019. Of those diagnosed, 6851 were subsequently hospitalised (10.7% with cancer), and 3227 died without being hospitalised (18.5% with cancer). Among those hospitalised, 1963 (22.5% with cancer) died. Cancer was associated with an increased risk of COVID\u201019 diagnosis (aHR: 1.08; 95% confidence interval [1.05\u20101.11]), direct COVID\u201019 hospitalisation (1.33 [1.24\u20101.43]) and death following hospitalisation (1.12 [1.01\u20101.25]). These associations were stronger for patients recently diagnosed with cancer, aged &lt;70\u2009years, and with haematological cancers. These patients should be prioritised in COVID\u201019 vaccination campaigns and continued non\u2010pharmaceutical interventions.<\/jats:p>","DOI":"10.1002\/ijc.33846","type":"journal-article","created":{"date-parts":[[2021,10,18]],"date-time":"2021-10-18T23:35:36Z","timestamp":1634600136000},"page":"782-794","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Cancer and the risk of coronavirus disease 2019 diagnosis, hospitalisation and death: A population\u2010based multistate cohort study including 4\u2009618\u2009377 adults in Catalonia, Spain"],"prefix":"10.1002","volume":"150","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1964-3546","authenticated-orcid":false,"given":"Elena","family":"Roel","sequence":"first","affiliation":[{"name":"Fundaci\u00f3 Institut Universitari per a la recerca a l'Atenci\u00f3 Prim\u00e0ria de Salut Jordi Gol i Gurina (IDIAPJGol)  Barcelona Spain"},{"name":"Universitat Aut\u00f2noma de Barcelona  Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Pistillo","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3 Institut Universitari per a la recerca a l'Atenci\u00f3 Prim\u00e0ria de Salut Jordi Gol i Gurina (IDIAPJGol)  Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2256-618X","authenticated-orcid":false,"given":"Martina","family":"Recalde","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3 Institut Universitari per a la recerca a l'Atenci\u00f3 Prim\u00e0ria de Salut Jordi Gol i Gurina (IDIAPJGol)  Barcelona Spain"},{"name":"Universitat Aut\u00f2noma de Barcelona  Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0029-6564","authenticated-orcid":false,"given":"Sergio","family":"Fern\u00e1ndez\u2010Bertol\u00edn","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3 Institut Universitari per a la recerca a l'Atenci\u00f3 Prim\u00e0ria de Salut Jordi Gol i Gurina (IDIAPJGol)  Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda","family":"Arag\u00f3n","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3 Institut Universitari per a la recerca a l'Atenci\u00f3 Prim\u00e0ria de Salut Jordi Gol i Gurina (IDIAPJGol)  Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6017-741X","authenticated-orcid":false,"given":"Isabelle","family":"Soerjomataram","sequence":"additional","affiliation":[{"name":"International Agency for Research on Cancer (IARC\u2010WHO)  Lyon France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mazda","family":"Jenab","sequence":"additional","affiliation":[{"name":"International Agency for Research on Cancer (IARC\u2010WHO)  Lyon 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