{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T13:53:50Z","timestamp":1779371630373,"version":"3.53.1"},"reference-count":33,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2022,5,17]],"date-time":"2022-05-17T00:00:00Z","timestamp":1652745600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000289","name":"Cancer Research UK","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000289","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008700","name":"Centre International de Recherche sur le Cancer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004484","name":"Tehran University of Medical Sciences and Health Services","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004484","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100013743","name":"World Cancer Research Fund International","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013743","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Red meat and processed meat are associated with some gastrointestinal cancers. Our study aims to investigate the association of different meat types with esophageal and gastric cancer (EC, GC) in a high\u2010risk population. The Golestan Cohort Study (GCS) is a population\u2010based cohort of 50\u2009045 individuals aged 40 to 75 from northeast Iran. Detailed data on different exposures were collected using validated questionnaires. We considered quintiles of meat consumption, using grams and density (g\/1000\u2009kcal\/day). We calculated intake of red, processed, organ and white meat, as well as total red meat, including the first three. We used proportional hazards regression models to estimate hazard ratios (HRs) and corresponding 95% confidence intervals (CIs) for the association between meat types and cancer. During 12\u2009years of follow\u2010up, out of 49\u2009585 participants (57.4% women), 369 developed EC (48.2% women) and 368 developed GC (27.5% women), including 309 esophageal squamous cell, 20 esophageal adenocarcinomas, 216 cardia and 95 non\u2010cardia GC. No association was found for EC except for red meat among females (HR for one quintile increase 1.13, 95% CI\u00a0=\u00a01.00\u20101.27). The risk of GC increased for intake of total red meat (HR 1.08, 95% CI\u00a0=\u00a01.00\u20101.17) and red meat separately (HR 1.09, 95% CI\u00a0=\u00a01.00\u20101.18). The HR for red meat and non\u2010cardia GC was 1.23 (95% CI\u00a0=\u00a01.02\u20101.48). No associations were observed for other types of meat. In conclusion, in this high\u2010risk population red meat intake is associated with GC, but not EC, suggesting a substantial role of this modifiable factor in determining the burden of GC.<\/jats:p>","DOI":"10.1002\/ijc.34056","type":"journal-article","created":{"date-parts":[[2022,4,30]],"date-time":"2022-04-30T15:33:08Z","timestamp":1651332788000},"page":"1005-1012","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Meat consumption and risk of esophageal and gastric cancer in the Golestan Cohort Study, Iran"],"prefix":"10.1002","volume":"151","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2309-7365","authenticated-orcid":false,"given":"Giulia","family":"Collatuzzo","sequence":"first","affiliation":[{"name":"Department of Medical and Surgical Sciences University of Bologna  Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3458-1072","authenticated-orcid":false,"given":"Arash","family":"Etemadi","sequence":"additional","affiliation":[{"name":"Metabolic Epidemiology Branch, Division of Cancer Epidemiology and Genetics National Cancer Institute  Bethesda Maryland USA"},{"name":"Digestive Oncology Research Center, Digestive Diseases Research Institute Tehran University of Medical Sciences, Shariati Hospital  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masoud","family":"Sotoudeh","sequence":"additional","affiliation":[{"name":"Digestive Oncology Research Center, Digestive Diseases Research Institute Tehran University of Medical Sciences, Shariati Hospital  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arash","family":"Nikmanesh","sequence":"additional","affiliation":[{"name":"Digestive Oncology Research Center, Digestive Diseases Research Institute Tehran University of Medical Sciences, Shariati Hospital  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hossein","family":"Poustchi","sequence":"additional","affiliation":[{"name":"Digestive Oncology Research Center, Digestive Diseases Research Institute Tehran University of Medical Sciences, Shariati Hospital  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masoud","family":"Khoshnia","sequence":"additional","affiliation":[{"name":"Digestive Oncology Research Center, Digestive Diseases Research Institute Tehran University of Medical Sciences, Shariati Hospital  Tehran Iran"},{"name":"Golestan Research Center of Gastroenterology and Hepatology Golestan University of Medical Sciences  Gorgan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akram","family":"Pourshams","sequence":"additional","affiliation":[{"name":"Digestive Oncology Research Center, Digestive Diseases Research Institute Tehran University of Medical Sciences, Shariati Hospital  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam","family":"Hashemian","sequence":"additional","affiliation":[{"name":"Digestive Oncology Research Center, Digestive Diseases Research Institute Tehran University of Medical Sciences, Shariati Hospital  Tehran Iran"},{"name":"Department of Biology, School of Art and Sciences Utica College  Utica New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gholamreza","family":"Roshandel","sequence":"additional","affiliation":[{"name":"Digestive Oncology Research Center, Digestive Diseases Research Institute Tehran University of Medical Sciences, Shariati Hospital  Tehran Iran"},{"name":"Golestan Research Center of Gastroenterology and Hepatology Golestan University of Medical Sciences  Gorgan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanford M.","family":"Dawsey","sequence":"additional","affiliation":[{"name":"Metabolic Epidemiology Branch, Division of Cancer Epidemiology and Genetics National Cancer Institute  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian C.","family":"Abnet","sequence":"additional","affiliation":[{"name":"Metabolic Epidemiology Branch, Division of Cancer Epidemiology and Genetics National Cancer Institute  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farin","family":"Kamangar","sequence":"additional","affiliation":[{"name":"Department of Biology, School of Computer, Mathematical, and Natural Sciences Morgan State University  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0518-8714","authenticated-orcid":false,"given":"Paul","family":"Brennan","sequence":"additional","affiliation":[{"name":"Section of Genetics International Agency for Research on Cancer  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Boffetta","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences University of Bologna  Bologna Italy"},{"name":"Stony Brook Cancer Center Stony Brook University  Stony Brook New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reza","family":"Malekzadeh","sequence":"additional","affiliation":[{"name":"Digestive Oncology Research Center, Digestive Diseases Research Institute Tehran University of Medical Sciences, Shariati Hospital  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,5,17]]},"reference":[{"key":"e_1_2_11_2_1","volume-title":"Red Meat and Processed Meat. 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Accessed November 10 2021."}],"container-title":["International Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.34056","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ijc.34056","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.34056","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,18]],"date-time":"2023-08-18T08:52:50Z","timestamp":1692348770000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ijc.34056"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,17]]},"references-count":33,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["10.1002\/ijc.34056"],"URL":"https:\/\/doi.org\/10.1002\/ijc.34056","archive":["Portico"],"relation":{},"ISSN":["0020-7136","1097-0215"],"issn-type":[{"value":"0020-7136","type":"print"},{"value":"1097-0215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,17]]},"assertion":[{"value":"2022-01-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}