{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T15:52:06Z","timestamp":1790351526001,"version":"4.1.0"},"reference-count":33,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2024,1,23]],"date-time":"2024-01-23T00:00:00Z","timestamp":1705968000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006636","name":"Forskningsr\u00e5det om H\u00e4lsa, Arbetsliv och V\u00e4lf\u00e4rd","doi-asserted-by":"publisher","award":["2019\u201000198"],"award-info":[{"award-number":["2019\u201000198"]}],"id":[{"id":"10.13039\/501100006636","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010733","name":"B\u00f8rnecancerfonden","doi-asserted-by":"publisher","award":["2018\u20103672"],"award-info":[{"award-number":["2018\u20103672"]}],"id":[{"id":"10.13039\/100010733","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006313","name":"Barncancerfonden","doi-asserted-by":"publisher","award":["PR2018\u20100097"],"award-info":[{"award-number":["PR2018\u20100097"]}],"id":[{"id":"10.13039\/501100006313","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2024,5,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Socioeconomic differences in overall survival from childhood cancer have been shown previously, but the underlying mechanisms remain unclear. We aimed to investigate if social inequalities were seen already for early mortality in settings with universal healthcare. From national registers, all children diagnosed with cancer at ages 0\u201319\u2009years, during 1991\u20132014, in Sweden and Denmark, were identified, and information on parental social characteristics was collected. We estimated odds ratios (OR) and 95% confidence intervals (CI) of early mortality (death within 90\u2009days after cancer diagnosis) by parental education, income, employment, cohabitation, and country of birth using logistic regression. For children with acute lymphoblastic leukaemia (ALL), clinical characteristics were obtained. Among 13,926 included children, 355 (2.5%) died within 90\u2009days after diagnosis. Indications of higher early mortality were seen among the disadvantaged groups, with the most pronounced associations observed for maternal education (OR\n                    <jats:sub>adj_Low_vs_High<\/jats:sub>\n                    1.65 [95% CI 1.22\u20132.23]) and income (OR\n                    <jats:sub>adj_Q1(lowest)_vs_Q4(highest)<\/jats:sub>\n                    1.77 [1.25\u20132.49]). We found attenuated or null associations between social characteristics and later mortality (deaths occurring 1\u20135\u2009years after cancer diagnosis). In children with ALL, the associations between social factors and early mortality remained unchanged when adjusting for potential mediation by clinical characteristics. In conclusion, this population\u2010based cohort study indicated differences in early mortality after childhood cancer by social background, also in countries with universal healthcare. Social differences occurring this early in the disease course requires further investigation, also regarding the timing of diagnosis.\n                  <\/jats:p>","DOI":"10.1002\/ijc.34851","type":"journal-article","created":{"date-parts":[[2024,1,23]],"date-time":"2024-01-23T09:44:23Z","timestamp":1706003063000},"page":"1719-1730","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Early mortality in children with cancer in Denmark and Sweden: The role of social background in a setting with universal healthcare"],"prefix":"10.1002","volume":"154","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5195-8065","authenticated-orcid":false,"given":"Hanna","family":"Mogensen","sequence":"first","affiliation":[{"name":"Unit of Epidemiology Institute of Environmental Medicine, Karolinska Institutet  Stockholm 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Bern\u2010Solothurn University of Bern  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gitte","family":"Vrelits S\u00f8rensen","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Adolescent Medicine Aarhus University Hospital  Aarhus Denmark"},{"name":"Department of Clinical Genetics Aalborg University Hospital  Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mats","family":"Talb\u00e4ck","sequence":"additional","affiliation":[{"name":"Unit of Epidemiology Institute of Environmental Medicine, Karolinska Institutet  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Tj\u00f8rnelund Nielsen","sequence":"additional","affiliation":[{"name":"Childhood Cancer Research Group Danish Cancer Institute  Copenhagen 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