{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T07:15:26Z","timestamp":1781075726899,"version":"3.54.1"},"reference-count":339,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000969","name":"American Institute for Cancer Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000969","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000321","name":"World Cancer Research Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000321","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013514","name":"Wereld Kanker Onderzoek Fonds","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013514","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The adiposity influence on colorectal cancer prognosis remains poorly characterised. We performed a systematic review and meta\u2010analysis on post\u2010diagnosis adiposity measures (body mass index [BMI], waist circumference, waist\u2010to\u2010hip ratio, weight) or their changes and colorectal cancer outcomes. PubMed and Embase were searched through 28 February 2022. Random\u2010effects meta\u2010analyses were conducted when at least three studies had sufficient information. The quality of evidence was interpreted and graded by the Global Cancer Update Programme (CUP Global) independent Expert Committee on Cancer Survivorship and Expert Panel. We reviewed 124 observational studies (85 publications). Meta\u2010analyses were possible for BMI and all\u2010cause mortality, colorectal cancer\u2010specific mortality, and cancer recurrence\/disease\u2010free survival. Non\u2010linear meta\u2010analysis indicated a reverse J\u2010shaped association between BMI and colorectal cancer outcomes (nadir at BMI 28\u2009kg\/m<jats:sup>2<\/jats:sup>). The highest risk, relative to the nadir, was observed at both ends of the BMI distribution (18 and 38\u2009kg\/m<jats:sup>2<\/jats:sup>), namely 60% and 23% higher risk for all\u2010cause mortality; 95% and 26% for colorectal cancer\u2010specific mortality; and 37% and 24% for cancer recurrence\/disease\u2010free survival, respectively. The higher risk with low BMI was attenuated in secondary analyses of RCTs (compared to cohort studies), among studies with longer follow\u2010up, and in women suggesting potential methodological limitations and\/or altered physiological state. Descriptively synthesised studies on other adiposity\u2010outcome associations of interest were limited in number and methodological quality. All the associations were graded as limited (likelihood of causality: no conclusion) due to potential methodological limitations (reverse causation, confounding, selection bias). Additional well\u2010designed observational studies and interventional trials are needed to provide further clarification.<\/jats:p>","DOI":"10.1002\/ijc.34905","type":"journal-article","created":{"date-parts":[[2024,5,2]],"date-time":"2024-05-02T00:15:11Z","timestamp":1714608911000},"page":"400-425","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Post\u2010diagnosis adiposity and colorectal cancer prognosis: A Global Cancer Update Programme (<scp>CUP<\/scp> Global) systematic literature review and meta\u2010analysis"],"prefix":"10.1002","volume":"155","author":[{"given":"Nerea","family":"Becerra\u2010Tom\u00e1s","sequence":"first","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health Imperial College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8481-579X","authenticated-orcid":false,"given":"Georgios","family":"Markozannes","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health Imperial College London  London UK"},{"name":"Department of Hygiene and Epidemiology University of Ioannina Medical School  Ioannina Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margarita","family":"Cariolou","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health Imperial College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katia","family":"Balducci","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health Imperial College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita","family":"Vieira","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health Imperial College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonia","family":"Kiss","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health Imperial College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4533-1722","authenticated-orcid":false,"given":"Dagfinn","family":"Aune","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health Imperial College London  London UK"},{"name":"Department of Nutrition Oslo New University College  Oslo Norway"},{"name":"Department of Research The Cancer Registry of Norway  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darren C.","family":"Greenwood","sequence":"additional","affiliation":[{"name":"Leeds Institute for Data Analytics, Faculty of Medicine and Health University of Leeds  Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laure","family":"Dossus","sequence":"additional","affiliation":[{"name":"Nutrition and Metabolism Branch, International Agency for Research on Cancer, World Health Organization  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen","family":"Copson","sequence":"additional","affiliation":[{"name":"Cancer Sciences Academic Unit, Faculty of Medicine University of Southampton  Southampton UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew G.","family":"Renehan","sequence":"additional","affiliation":[{"name":"The Christie NHS Foundation Trust, Manchester Cancer Research Centre, NIHR Manchester Biomedical Research Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health University of Manchester  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martijn","family":"Bours","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, GROW School for Oncology and Reproduction Maastricht University  Maastricht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5241-932X","authenticated-orcid":false,"given":"Wendy","family":"Demark\u2010Wahnefried","sequence":"additional","affiliation":[{"name":"O'Neal Comprehensive Cancer Center University of Alabama at Birmingham  Birmingham Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa M.","family":"Hudson","sequence":"additional","affiliation":[{"name":"Department of Oncology St Jude Children's Research Hospital  Memphis Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne M.","family":"May","sequence":"additional","affiliation":[{"name":"Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht Utrecht University  Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Folakemi T.","family":"Odedina","sequence":"additional","affiliation":[{"name":"Mayo Clinic Comprehensive Cancer Center  Jacksonville Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roderick","family":"Skinner","sequence":"additional","affiliation":[{"name":"Department of Paediatric and Adolescent Haematology\/Oncology, Great North Children's Hospital and Translational and Clinical Research Institute, and Centre for Cancer Newcastle University  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Steindorf","sequence":"additional","affiliation":[{"name":"Division of Physical Activity Prevention and Cancer, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT)  Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Tj\u00f8nneland","sequence":"additional","affiliation":[{"name":"Danish Cancer Society Research Center, Diet, Cancer and Health  Copenhagen Denmark"},{"name":"Department of Public Health University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Galina","family":"Velikova","sequence":"additional","affiliation":[{"name":"School of Medicine, Faculty of Medicine and Health University of Leeds  Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica L.","family":"Baskin","sequence":"additional","affiliation":[{"name":"UPMC Hillman Cancer Center  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajiv","family":"Chowdhury","sequence":"additional","affiliation":[{"name":"Department of Global Health Robert Stempel College of Public Health and Social Work, Florida International University  Miami Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynette","family":"Hill","sequence":"additional","affiliation":[{"name":"World Cancer Research Fund International  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah J.","family":"Lewis","sequence":"additional","affiliation":[{"name":"Department of Population Health Sciences, Bristol Medical School University of Bristol  Bristol UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaap","family":"Seidell","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, Faculty of Science Vrije Universiteit Amsterdam  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matty P.","family":"Weijenberg","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, GROW School for Oncology and Reproduction Maastricht University  Maastricht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Krebs","sequence":"additional","affiliation":[{"name":"Department of Biology University of Oxford  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda J.","family":"Cross","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health Imperial College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8452-8472","authenticated-orcid":false,"given":"Konstantinos K.","family":"Tsilidis","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health Imperial College London  London UK"},{"name":"Department of Hygiene and Epidemiology University of Ioannina Medical School  Ioannina Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0198-1897","authenticated-orcid":false,"given":"Doris S. M.","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health Imperial College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,5]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2022-327736"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tranon.2021.101174"},{"key":"e_1_2_11_5_1","first-page":"175","article-title":"Global pattern and trends of colorectal cancer survival: a systematic review of population\u2010based registration data","volume":"19","author":"Jiang YF","year":"2022","journal-title":"Cancer Biol Med"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21262"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/jpm5030243"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)32129-3"},{"key":"e_1_2_11_9_1","volume-title":"Diet, Nutrition, Physical Activity and Cancer: A Global Perspective","author":"World Cancer Research Fund\/American Institute for Cancer Research","year":"2018"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-014-0450-y"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-014-0435-x"},{"key":"e_1_2_11_12_1","article-title":"Association between body mass index and prognosis of colorectal cancer: a meta\u2010analysis of prospective cohort studies","volume":"10","author":"Lee J","year":"2015","journal-title":"PLos One"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/nutrit\/nuac005"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2022.05.020"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.34322"},{"key":"e_1_2_11_16_1","unstructured":"Global Cancer Update Programme (CUP Global). Accessed November 2022.https:\/\/www.wcrf.org\/diet-activity-and-cancer\/global-cancer-update-programme\/about-the-global-cancer-update-programme\/"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.34906"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.34903"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.34904"},{"key":"e_1_2_11_20_1","unstructured":"ChanDSM TsilidisK Becerra\u2010TomasN et al.Global Cancer Update Programme Protocol for the data collection and systematic literature review on the role of diet body fatness and physical activity on survival after colorectal cancer. Accessed November 17 2022.https:\/\/osf.io\/r5ud2\/registrations"},{"key":"e_1_2_11_21_1","unstructured":"USDA Nutrition Evidence Systematic Review. Risk of Bias for Nutrition Observational Studies (RoB\u2010NObs) Tool. Accessed November 2022.https:\/\/nesr.usda.gov\/sites\/default\/files\/2019\u201007\/RiskOfBiasForNutritionObservationalStudies\u2010RoB\u2010NObs.pdf"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i4919"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/0197-2456(86)90046-2"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/1536867X211025798"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwn005"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdr398"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a116237"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1177\/1536867X0600600103"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.3013"},{"key":"e_1_2_11_30_1","first-page":"i","article-title":"Obesity: preventing and managing the global epidemic. Report of a WHO consultation","volume":"894","year":"2000","journal-title":"World Health Organ Tech Rep Ser"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2016.0732"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.11544"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2004.07.121"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2021.09.028"},{"key":"e_1_2_11_35_1","first-page":"pkaa024","volume-title":"Body Mass Index and Weight Loss in Metastatic Colorectal Cancer in CALGB (Alliance)\/SWOG 80405","author":"Guercio BJ","year":"2020"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers11050609"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13143592"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djj442"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.1186"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-8-79"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/jrsm.1230"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.38.0287"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/nqaa394"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41416-020-01155-2"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.315.7109.629"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnesp.2020.07.010"},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10147-021-02062-z"},{"key":"e_1_2_11_48_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-021-04039-w"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.13594"},{"key":"e_1_2_11_50_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers12071986"},{"key":"e_1_2_11_51_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/nqz230"},{"key":"e_1_2_11_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2015.05.059"},{"key":"e_1_2_11_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2018.03.031"},{"key":"e_1_2_11_54_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12029-017-0047-2"},{"key":"e_1_2_11_55_1","first-page":"815","article-title":"Site\u2010specific evaluation of prognostic factors on survival in Iranian colorectal cancer patients: a competing risks survival analysis","volume":"10","author":"Asghari\u2010Jafarabadi M","year":"2009","journal-title":"Asian Pac J Cancer Prev"},{"key":"e_1_2_11_56_1","doi-asserted-by":"publisher","DOI":"10.15430\/JCP.2020.25.1.38"},{"key":"e_1_2_11_57_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0b013e3182880ffa"},{"key":"e_1_2_11_58_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-013-1748-z"},{"key":"e_1_2_11_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.suronc.2021.101562"},{"key":"e_1_2_11_60_1","doi-asserted-by":"publisher","DOI":"10.7314\/APJCP.2014.15.15.6253"},{"key":"e_1_2_11_61_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13304-019-00631-6"},{"key":"e_1_2_11_62_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.22031"},{"key":"e_1_2_11_63_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-010-0908-4"},{"key":"e_1_2_11_64_1","doi-asserted-by":"publisher","DOI":"10.1080\/02656736.2017.1371342"},{"key":"e_1_2_11_65_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.14107"},{"key":"e_1_2_11_66_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-012-1563-y"},{"key":"e_1_2_11_67_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph18157734"},{"key":"e_1_2_11_68_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-17-0200"},{"key":"e_1_2_11_69_1","doi-asserted-by":"publisher","DOI":"10.1080\/01635581.2017.1285038"},{"key":"e_1_2_11_70_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2020.36330"},{"key":"e_1_2_11_71_1","doi-asserted-by":"publisher","DOI":"10.7314\/APJCP.2012.13.3.1059"},{"key":"e_1_2_11_72_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-019-5319-8"},{"key":"e_1_2_11_73_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-018-3843-5"},{"key":"e_1_2_11_74_1","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2020.11617"},{"key":"e_1_2_11_75_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14030489"},{"key":"e_1_2_11_76_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.21.01784"},{"key":"e_1_2_11_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2010.03.010"},{"key":"e_1_2_11_78_1","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2016.31.10.1571"},{"key":"e_1_2_11_79_1","doi-asserted-by":"publisher","DOI":"10.3857\/roj.2016.01725"},{"key":"e_1_2_11_80_1","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-10-0614"},{"key":"e_1_2_11_81_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers12010060"},{"key":"e_1_2_11_82_1","doi-asserted-by":"publisher","DOI":"10.5009\/gnl16526"},{"key":"e_1_2_11_83_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12029-018-0056-9"},{"key":"e_1_2_11_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(98)02309-5"},{"key":"e_1_2_11_85_1","first-page":"34","article-title":"Overweight is associated with better prognosis in metastatic colorectal cancer patients treated with bevacizumab plus FOLFOX chemotherapy","volume":"24","author":"Cybulska\u2010Stopa B","year":"2020","journal-title":"Contemp Oncol (Pozn)"},{"key":"e_1_2_11_86_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2021.671547"},{"key":"e_1_2_11_87_1","doi-asserted-by":"publisher","DOI":"10.21873\/anticanres.12802"},{"key":"e_1_2_11_88_1","doi-asserted-by":"publisher","DOI":"10.1111\/ans.16758"},{"key":"e_1_2_11_89_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.12026"},{"key":"e_1_2_11_90_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-019-02072-0"},{"key":"e_1_2_11_91_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12357"},{"key":"e_1_2_11_92_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.52.6.868"},{"key":"e_1_2_11_93_1","first-page":"473","article-title":"Prognostic analysis of colorectal cancer patients with diabetes mellitus in China\u2014the experience of a single institution","volume":"20","author":"Feng JF","year":"2011","journal-title":"Adv Clin Exp Med"},{"key":"e_1_2_11_94_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v22.i45.9984"},{"key":"e_1_2_11_95_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-020-09049-6"},{"key":"e_1_2_11_96_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2017.04.44"},{"key":"e_1_2_11_97_1","doi-asserted-by":"publisher","DOI":"10.1177\/0284185120918373"},{"key":"e_1_2_11_98_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2019.07.011"},{"key":"e_1_2_11_99_1","doi-asserted-by":"publisher","DOI":"10.3892\/mco.2021.2346"},{"key":"e_1_2_11_100_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-15-1336"},{"key":"e_1_2_11_101_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2009.188946"},{"key":"e_1_2_11_102_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejcn.1602029"},{"key":"e_1_2_11_103_1","doi-asserted-by":"publisher","DOI":"10.4143\/crt.2019.249"},{"key":"e_1_2_11_104_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-020-03577-z"},{"key":"e_1_2_11_105_1","doi-asserted-by":"publisher","DOI":"10.4314\/jmbs.v6i1.5"},{"key":"e_1_2_11_106_1","doi-asserted-by":"publisher","DOI":"10.21873\/invivo.12724"},{"key":"e_1_2_11_107_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-010-0963-0"},{"key":"e_1_2_11_108_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2017.11.032"},{"key":"e_1_2_11_109_1","doi-asserted-by":"publisher","DOI":"10.4183\/aeb.2017.425"},{"key":"e_1_2_11_110_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000001352"},{"key":"e_1_2_11_111_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12957-020-01836-5"},{"key":"e_1_2_11_112_1","first-page":"333","article-title":"Prognostic factors affecting short\u2010 and long\u2010term recurrence\u2010free survival of patients with rectal cancer using cure models: a cohort study","volume":"45","author":"Hosseini SV","year":"2020","journal-title":"Iran J Med Sci"},{"key":"e_1_2_11_113_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7819-10-76"},{"key":"e_1_2_11_114_1","doi-asserted-by":"publisher","DOI":"10.7150\/jca.26637"},{"key":"e_1_2_11_115_1","doi-asserted-by":"publisher","DOI":"10.1177\/15330338211037418"},{"key":"e_1_2_11_116_1","doi-asserted-by":"publisher","DOI":"10.21037\/atm-20-3751"},{"key":"e_1_2_11_117_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2013.350"},{"key":"e_1_2_11_118_1","first-page":"3291","article-title":"Clinical significance of tumor pathology for postoperative survival of patients undergoing surgery for stage IV colorectal cancer","volume":"32","author":"Ishizuka M","year":"2012","journal-title":"Anticancer Res"},{"key":"e_1_2_11_119_1","doi-asserted-by":"publisher","DOI":"10.1097\/MJT.0000000000000859"},{"key":"e_1_2_11_120_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0076125"},{"key":"e_1_2_11_121_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-014-2418-6"},{"key":"e_1_2_11_122_1","doi-asserted-by":"publisher","DOI":"10.21037\/jgo-20-48"},{"key":"e_1_2_11_123_1","doi-asserted-by":"publisher","DOI":"10.1097\/CAD.0000000000000201"},{"key":"e_1_2_11_124_1","doi-asserted-by":"publisher","DOI":"10.3892\/mco.2016.964"},{"key":"e_1_2_11_125_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-011-1333-2"},{"key":"e_1_2_11_126_1","doi-asserted-by":"publisher","DOI":"10.1177\/1078155220959427"},{"key":"e_1_2_11_127_1","doi-asserted-by":"publisher","DOI":"10.3393\/ac.2019.04.22"},{"key":"e_1_2_11_128_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2021.10.001"},{"key":"e_1_2_11_129_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2017.11.038"},{"key":"e_1_2_11_130_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-018-6828-4"},{"key":"e_1_2_11_131_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-017-4255-5"},{"key":"e_1_2_11_132_1","doi-asserted-by":"publisher","DOI":"10.7314\/APJCP.2015.16.12.4853"},{"key":"e_1_2_11_133_1","first-page":"4171","article-title":"Clinical value of serum p53 antibody in the diagnosis and prognosis of colorectal cancer","volume":"36","author":"Kunizaki M","year":"2016","journal-title":"Anticancer Res"},{"key":"e_1_2_11_134_1","first-page":"533","article-title":"Prognostic significance of unintentional body weight loss in colon cancer patients","volume":"8","author":"Kuo YH","year":"2018","journal-title":"Mol Clin Oncol"},{"key":"e_1_2_11_135_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-018-3038-2"},{"key":"e_1_2_11_136_1","doi-asserted-by":"publisher","DOI":"10.4103\/jmas.JMAS_68_17"},{"key":"e_1_2_11_137_1","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2017.32.12.1974"},{"key":"e_1_2_11_138_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12957-020-02006-3"},{"key":"e_1_2_11_139_1","doi-asserted-by":"publisher","DOI":"10.4174\/jkss.2013.85.1.35"},{"key":"e_1_2_11_140_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-01086-9"},{"key":"e_1_2_11_141_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-018-3065-z"},{"key":"e_1_2_11_142_1","doi-asserted-by":"publisher","DOI":"10.7150\/jca.14797"},{"key":"e_1_2_11_143_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.23932"},{"key":"e_1_2_11_144_1","doi-asserted-by":"publisher","DOI":"10.4174\/astr.2019.96.3.116"},{"key":"e_1_2_11_145_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2017.06.028"},{"key":"e_1_2_11_146_1","first-page":"158","article-title":"Overweight but not obesity is associated with decreased survival in rectal cancer","volume":"22","author":"Lino\u2010Silva LS","year":"2018","journal-title":"Contemp Oncol (Pozn)"},{"key":"e_1_2_11_147_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7819-11-271"},{"key":"e_1_2_11_148_1","doi-asserted-by":"publisher","DOI":"10.2147\/CMAR.S268928"},{"key":"e_1_2_11_149_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-63644-x"},{"key":"e_1_2_11_150_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2022.796601"},{"key":"e_1_2_11_151_1","article-title":"Comparative analysis of circulating biomarkers for patients undergoing resection of colorectal liver metastases","volume":"11","author":"Loosen SH","year":"2021","journal-title":"Diagnostics (Basel)"},{"key":"e_1_2_11_152_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2014.03.023"},{"key":"e_1_2_11_153_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.10075"},{"key":"e_1_2_11_154_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0068206"},{"key":"e_1_2_11_155_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10147-019-01580-1"},{"key":"e_1_2_11_156_1","doi-asserted-by":"publisher","DOI":"10.1093\/bjsopen\/zrab078"},{"key":"e_1_2_11_157_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2017.05.017"},{"key":"e_1_2_11_158_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-012-2436-x"},{"key":"e_1_2_11_159_1","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/3109165"},{"key":"e_1_2_11_160_1","first-page":"54","article-title":"Evaluation of prognostic factors effect on survival time in patients with colorectal cancer, based on Weibull competing\u2010risks model","volume":"10","author":"Moamer S","year":"2017","journal-title":"Gastroenterol Hepatol Bed Bench"},{"key":"e_1_2_11_161_1","first-page":"1","article-title":"Survival analysis of colorectal cancer patients using exponentiated Weibull distribution","volume":"11","author":"Moein Y","year":"2018","journal-title":"Int J Cancer Manag"},{"key":"e_1_2_11_162_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-013-2156-9"},{"key":"e_1_2_11_163_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-008-9891-4"},{"key":"e_1_2_11_164_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00595-012-0352-0"},{"key":"e_1_2_11_165_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-019-03488-8"},{"key":"e_1_2_11_166_1","doi-asserted-by":"publisher","DOI":"10.2147\/CMAR.S255332"},{"key":"e_1_2_11_167_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000002071"},{"key":"e_1_2_11_168_1","doi-asserted-by":"publisher","DOI":"10.4174\/astr.2020.99.3.153"},{"key":"e_1_2_11_169_1","doi-asserted-by":"publisher","DOI":"10.1159\/000442527"},{"key":"e_1_2_11_170_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-021-03934-6"},{"key":"e_1_2_11_171_1","doi-asserted-by":"publisher","DOI":"10.1097\/COC.0000000000000150"},{"key":"e_1_2_11_172_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000002990"},{"key":"e_1_2_11_173_1","first-page":"10","article-title":"The elevated pre\u2010treatment C\u2010reactive protein predicts poor prognosis in patients with locally advanced rectal cancer treated with neo\u2010adjuvant radiochemotherapy","volume":"10","author":"Partl R","year":"2020","journal-title":"Diagnostics (Basel)"},{"key":"e_1_2_11_174_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2009.09.004"},{"key":"e_1_2_11_175_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2021.694997"},{"key":"e_1_2_11_176_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.soard.2020.10.022"},{"key":"e_1_2_11_177_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-021-04043-0"},{"key":"e_1_2_11_178_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-019-05073-0"},{"key":"e_1_2_11_179_1","doi-asserted-by":"publisher","DOI":"10.21873\/invivo.11467"},{"key":"e_1_2_11_180_1","doi-asserted-by":"publisher","DOI":"10.2147\/CMAR.S290416"},{"key":"e_1_2_11_181_1","doi-asserted-by":"publisher","DOI":"10.3747\/co.23.2809"},{"key":"e_1_2_11_182_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12664-018-0923-0"},{"key":"e_1_2_11_183_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/dju333"},{"key":"e_1_2_11_184_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-012-2045-9"},{"key":"e_1_2_11_185_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-021-10289-3"},{"key":"e_1_2_11_186_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-010-1410-8"},{"key":"e_1_2_11_187_1","doi-asserted-by":"publisher","DOI":"10.4103\/jcrt.JCRT_326_18"},{"key":"e_1_2_11_188_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-67285-y"},{"key":"e_1_2_11_189_1","first-page":"5735","article-title":"Obesity is a risk factor for multifocal disease and recurrence after colorectal cancer surgery: a case\u2013control study","volume":"34","author":"Scarpa M","year":"2014","journal-title":"Anticancer Res"},{"key":"e_1_2_11_190_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgo.2018.05.001"},{"key":"e_1_2_11_191_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.29440"},{"key":"e_1_2_11_192_1","doi-asserted-by":"publisher","DOI":"10.1097\/CEJ.0000000000000482"},{"key":"e_1_2_11_193_1","first-page":"62","article-title":"Body mass index influences long\u2010term outcome in patients with colorectal cancer","volume":"57","author":"Shibakita M","year":"2010","journal-title":"Hepatogastroenterology"},{"key":"e_1_2_11_194_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-020-01516-6"},{"key":"e_1_2_11_195_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2010.02348.x"},{"key":"e_1_2_11_196_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-09-2636"},{"key":"e_1_2_11_197_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.39.2563"},{"key":"e_1_2_11_198_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djx253"},{"key":"e_1_2_11_199_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.33649"},{"key":"e_1_2_11_200_1","doi-asserted-by":"publisher","DOI":"10.4174\/astr.2019.96.2.86"},{"key":"e_1_2_11_201_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v21.i43.12410"},{"key":"e_1_2_11_202_1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/1509140"},{"key":"e_1_2_11_203_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0195406"},{"key":"e_1_2_11_204_1","doi-asserted-by":"publisher","DOI":"10.2147\/CMAR.S234688"},{"key":"e_1_2_11_205_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.2930270407"},{"key":"e_1_2_11_206_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10147-016-1016-7"},{"key":"e_1_2_11_207_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.14793"},{"key":"e_1_2_11_208_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000000458"},{"key":"e_1_2_11_209_1","first-page":"5639","article-title":"Preoperative lower body mass index correlates with poorer prognosis in patients undergoing curative laparoscopic surgery for colorectal cancer","volume":"35","author":"Uratani R","year":"2015","journal-title":"Anticancer Res"},{"key":"e_1_2_11_210_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2018.0126"},{"key":"e_1_2_11_211_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.7823"},{"key":"e_1_2_11_212_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2018.05.029"},{"key":"e_1_2_11_213_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6606005"},{"key":"e_1_2_11_214_1","first-page":"216","article-title":"High expression of AMPD2 and obesity are associated with poor prognosis in colorectal cancer","volume":"11","author":"Wang F","year":"2018","journal-title":"Int J Clin Exp Pathol"},{"key":"e_1_2_11_215_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-65091-0"},{"key":"e_1_2_11_216_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v26.i42.6638"},{"key":"e_1_2_11_217_1","doi-asserted-by":"publisher","DOI":"10.4143\/crt.2019.695"},{"key":"e_1_2_11_218_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.6517"},{"key":"e_1_2_11_219_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000016066"},{"key":"e_1_2_11_220_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1743-7563.2011.01512.x"},{"key":"e_1_2_11_221_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.33671"},{"key":"e_1_2_11_222_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.16597"},{"key":"e_1_2_11_223_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2021.710423"},{"key":"e_1_2_11_224_1","doi-asserted-by":"publisher","DOI":"10.18632\/aging.103972"},{"key":"e_1_2_11_225_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-018-5723-5"},{"key":"e_1_2_11_226_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000000479"},{"key":"e_1_2_11_227_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.8334"},{"key":"e_1_2_11_228_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i43.16258"},{"key":"e_1_2_11_229_1","doi-asserted-by":"publisher","DOI":"10.1177\/17246008211022769"},{"key":"e_1_2_11_230_1","doi-asserted-by":"publisher","DOI":"10.1080\/01635581.2021.1957130"},{"key":"e_1_2_11_231_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2020.585083"},{"key":"e_1_2_11_232_1","doi-asserted-by":"publisher","DOI":"10.31557\/APJCP.2021.22.11.3705"},{"key":"e_1_2_11_233_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00595-019-01778-w"},{"key":"e_1_2_11_234_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.6182"},{"key":"e_1_2_11_235_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2021.741309"},{"key":"e_1_2_11_236_1","doi-asserted-by":"publisher","DOI":"10.21037\/jgo-21-781"},{"key":"e_1_2_11_237_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-8049(97)10090-9"},{"key":"e_1_2_11_238_1","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.118.210161"},{"key":"e_1_2_11_239_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-012-0071-2"},{"key":"e_1_2_11_240_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v18.i31.4191"},{"key":"e_1_2_11_241_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12029-012-9472-4"},{"key":"e_1_2_11_242_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-015-1147-z"},{"key":"e_1_2_11_243_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-11-0079"},{"key":"e_1_2_11_244_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aer444"},{"key":"e_1_2_11_245_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11764-010-0141-y"},{"key":"e_1_2_11_246_1","doi-asserted-by":"publisher","DOI":"10.7314\/APJCP.2016.17.3.1193"},{"key":"e_1_2_11_247_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12234"},{"key":"e_1_2_11_248_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3181a3e52b"},{"key":"e_1_2_11_249_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.30932"},{"key":"e_1_2_11_250_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clcc.2015.07.002"},{"key":"e_1_2_11_251_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-16-0145"},{"key":"e_1_2_11_252_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2017.07.022"},{"key":"e_1_2_11_253_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.je.2016.12.004"},{"key":"e_1_2_11_254_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.116.136531"},{"key":"e_1_2_11_255_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2007.15.6687"},{"key":"e_1_2_11_256_1","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.490"},{"key":"e_1_2_11_257_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00595-014-0899-z"},{"key":"e_1_2_11_258_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2015.61.6441"},{"key":"e_1_2_11_259_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-015-1704-0"},{"key":"e_1_2_11_260_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.27938"},{"key":"e_1_2_11_261_1","first-page":"199","article-title":"Does the prognosis of colorectal cancer vary with tumor site?","volume":"4","author":"Jafarabadi MA","year":"2011","journal-title":"Gastroenterol Hepatol Bed Bench"},{"key":"e_1_2_11_262_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0209307"},{"key":"e_1_2_11_263_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000010843"},{"key":"e_1_2_11_264_1","doi-asserted-by":"publisher","DOI":"10.1080\/01635581.2019.1679198"},{"key":"e_1_2_11_265_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00432-016-2225-1"},{"key":"e_1_2_11_266_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clcc.2020.02.010"},{"key":"e_1_2_11_267_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2018.09.012"},{"key":"e_1_2_11_268_1","first-page":"1","article-title":"Validation of the survival benefits of metformin in middle eastern patients with type II diabetes mellitus and colorectal cancer","volume":"4","author":"Al Omari A","year":"2018","journal-title":"J Glob Oncol"},{"key":"e_1_2_11_269_1","doi-asserted-by":"publisher","DOI":"10.1159\/000479852"},{"key":"e_1_2_11_270_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-012-1496-5"},{"key":"e_1_2_11_271_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-008-0463-7"},{"key":"e_1_2_11_272_1","first-page":"125","article-title":"Estimating the cure proportion of colorectal cancer and related factors after surgery in patients using parametric cure models","volume":"13","author":"Izadi N","year":"2020","journal-title":"Gastroenterol Hepatol Bed Bench"},{"key":"e_1_2_11_273_1","first-page":"653","article-title":"Predictors of survival in stage IV metastatic colorectal cancer","volume":"30","author":"Zacharakis M","year":"2010","journal-title":"Anticancer Res"},{"key":"e_1_2_11_274_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdh267"},{"key":"e_1_2_11_275_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0218761"},{"key":"e_1_2_11_276_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-76643-9"},{"key":"e_1_2_11_277_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2011.06.038"},{"key":"e_1_2_11_278_1","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2019-0590"},{"key":"e_1_2_11_279_1","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.2787"},{"key":"e_1_2_11_280_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2019.11.512"},{"key":"e_1_2_11_281_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2020.10.039"},{"key":"e_1_2_11_282_1","doi-asserted-by":"publisher","DOI":"10.5812\/ijcm.7352"},{"key":"e_1_2_11_283_1","doi-asserted-by":"publisher","DOI":"10.3109\/02841869409098438"},{"key":"e_1_2_11_284_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.24598"},{"key":"e_1_2_11_285_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.24706"},{"key":"e_1_2_11_286_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clcc.2019.07.005"},{"key":"e_1_2_11_287_1","first-page":"200","article-title":"Risk of relapse and death from colorectal cancer and its related factors using non\u2010Markovian multi\u2010state model","volume":"13","author":"Hajebi Khaniki S","year":"2020","journal-title":"Gastroenterol Hepatol Bed Bench"},{"key":"e_1_2_11_288_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2018.00620"},{"key":"e_1_2_11_289_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.26619"},{"key":"e_1_2_11_290_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12029-021-00609-x"},{"key":"e_1_2_11_291_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13304-020-00959-4"},{"key":"e_1_2_11_292_1","doi-asserted-by":"publisher","DOI":"10.1080\/01635581.2021.1900300"},{"key":"e_1_2_11_293_1","doi-asserted-by":"publisher","DOI":"10.5812\/ijcm.110257"},{"key":"e_1_2_11_294_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2021.04.002"},{"key":"e_1_2_11_295_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-79657-5"},{"key":"e_1_2_11_296_1","doi-asserted-by":"publisher","DOI":"10.5009\/gnl20266"},{"key":"e_1_2_11_297_1","doi-asserted-by":"publisher","DOI":"10.1159\/000504507"},{"key":"e_1_2_11_298_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.33775"},{"key":"e_1_2_11_299_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000001746"},{"key":"e_1_2_11_300_1","doi-asserted-by":"publisher","DOI":"10.1002\/cnr2.1346"},{"key":"e_1_2_11_301_1","doi-asserted-by":"publisher","DOI":"10.1111\/ans.16706"},{"key":"e_1_2_11_302_1","doi-asserted-by":"publisher","DOI":"10.1002\/onco.13774"},{"key":"e_1_2_11_303_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu13051604"},{"key":"e_1_2_11_304_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13102442"},{"key":"e_1_2_11_305_1","doi-asserted-by":"publisher","DOI":"10.4178\/epih.e2018045"},{"key":"e_1_2_11_306_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-016-2668-5"},{"key":"e_1_2_11_307_1","first-page":"S37","article-title":"Mixture cure model for estimating short\u2010term and long\u2010term colorectal cancer survival","volume":"12","author":"Amanpour F","year":"2019","journal-title":"Gastroenterol Hepatol Bed Bench"},{"key":"e_1_2_11_308_1","doi-asserted-by":"publisher","DOI":"10.4143\/crt.2021.656"},{"key":"e_1_2_11_309_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12957-021-02460-7"},{"key":"e_1_2_11_310_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2018.07.031"},{"key":"e_1_2_11_311_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2012.267"},{"key":"e_1_2_11_312_1","first-page":"11","article-title":"Effect of metabolic syndrome and individual components on colon cancer characteristics and prognosis","author":"Silva A","year":"2021","journal-title":"Front Oncol"},{"key":"e_1_2_11_313_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI10842"},{"key":"e_1_2_11_314_1","doi-asserted-by":"publisher","DOI":"10.5114\/aoms.2016.58928"},{"key":"e_1_2_11_315_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/94.13.972"},{"key":"e_1_2_11_316_1","doi-asserted-by":"publisher","DOI":"10.1080\/13813450801954303"},{"key":"e_1_2_11_317_1","article-title":"adiponectin, and survival in metastatic colorectal cancer: results from CALGB (Alliance)\/SWOG 80405","volume":"5","author":"Guercio BJ","year":"2020","journal-title":"JNCI Cancer Spectr"},{"key":"e_1_2_11_318_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.17.9945"},{"key":"e_1_2_11_319_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-08-0480"},{"key":"e_1_2_11_320_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v25.i31.4383"},{"key":"e_1_2_11_321_1","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.4143"},{"key":"e_1_2_11_322_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-020-01817-1"},{"key":"e_1_2_11_323_1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/1053125"},{"key":"e_1_2_11_324_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdr277"},{"key":"e_1_2_11_325_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-021-06626-7"},{"key":"e_1_2_11_326_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.298.17.2028"},{"key":"e_1_2_11_327_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2016.0868"},{"key":"e_1_2_11_328_1","doi-asserted-by":"publisher","DOI":"10.1097\/SPC.0000000000000382"},{"key":"e_1_2_11_329_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trecan.2018.10.001"},{"key":"e_1_2_11_330_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13539-013-0111-0"},{"key":"e_1_2_11_331_1","doi-asserted-by":"publisher","DOI":"10.1586\/17474124.2015.1089170"},{"key":"e_1_2_11_332_1","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2006.269"},{"key":"e_1_2_11_333_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i2156"},{"key":"e_1_2_11_334_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyu276"},{"key":"e_1_2_11_335_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-17-3043"},{"key":"e_1_2_11_336_1","doi-asserted-by":"publisher","DOI":"10.1097\/NT.0000000000000092"},{"key":"e_1_2_11_337_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-17-3287"},{"key":"e_1_2_11_338_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0954422409990035"},{"key":"e_1_2_11_339_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-33563-z"},{"key":"e_1_2_11_340_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.4456"}],"container-title":["International Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.34905","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,6]],"date-time":"2025-04-06T00:59:19Z","timestamp":1743901159000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ijc.34905"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":339,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,8]]}},"alternative-id":["10.1002\/ijc.34905"],"URL":"https:\/\/doi.org\/10.1002\/ijc.34905","archive":["Portico"],"relation":{},"ISSN":["0020-7136","1097-0215"],"issn-type":[{"value":"0020-7136","type":"print"},{"value":"1097-0215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"2023-07-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}