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The aim of this study was to identify the prognostic factors of salivary carcinomas of the tongue in a population\u2010based cohort. This retrospective multicentric study, based on the \u201cR\u00e9seau d'Expertise Fran\u00e7ais sur les Cancers ORL Rares\u201d (REFCOR), included all the patients with a salivary carcinoma of the tongue, diagnosed between January 2009 and December 2018. Dubious slides were reviewed by REFCOR expert pathologists to ensure diagnostic accuracy. Treatment was performed in accordance with national REFCOR recommendations. From 28 centers, 103 patients were included in this study. Median age at diagnosis was 63\u2009years, and 60.2% were female. Tumors were adenoid cystic carcinomas (41.7%), mucoepidermoid carcinomas (30.1%), and other adenocarcinomas (28.2%). Primary treatment was surgical for 61.2% of them. Five\u2010year overall survival (OS) and event\u2010free survival (EFS) rates were 84.7% and 38.6%, respectively. In multivariable analysis, EFS was significantly worse in case of nonsurgical treatment, alcohol consumption, and glossotonsillar sulcus involvement. N\u2010positive status was the only significant prognostic factor for OS in multivariable analysis. Salivary carcinomas of the tongue represent a heterogeneous group of rare tumors, with a high risk of recurrence. In this national cohort, surgery was associated with better EFS and N\u2010status was the main independent prognostic factor for OS.<\/jats:p>","DOI":"10.1002\/ijc.35167","type":"journal-article","created":{"date-parts":[[2024,9,20]],"date-time":"2024-09-20T10:24:14Z","timestamp":1726827854000},"page":"310-321","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Malignant salivary gland tumors of the tongue: <scp>A<\/scp> multicenter <scp>REFCOR<\/scp> study"],"prefix":"10.1002","volume":"156","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6676-0916","authenticated-orcid":false,"given":"Valentine","family":"Poissonnet","sequence":"first","affiliation":[{"name":"Otolaryngology, Head and Neck Surgery Department University Cancer Institute Toulouse and Toulouse University Hospital, Larrey Hospital  Toulouse 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