{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:44:37Z","timestamp":1786977877115,"version":"build-2736575974"},"reference-count":48,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,10,3]],"date-time":"2024-10-03T00:00:00Z","timestamp":1727913600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2025,2,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Treatment modifications and contact restrictions were common during the COVID\u201019 pandemic and can be stressors for mental health. There is a lack of studies assessing pandemic\u2010related risk factors for anxiety and depression of cancer patients and survivors systematically in multifactorial models. A total of 2391 participants, mean age 65.5\u2009years, \u22645\u2009years post\u2010diagnosis of either lung, prostate, breast, colorectal cancer, or leukemia\/lymphoma, were recruited in 2021 via the Baden\u2010W\u00fcrttemberg Cancer Registry, Germany. Sociodemographic information, pandemic\u2010related treatment modifications, contact restrictions, and anxiety\/depression (Hospital Anxiety and Depression Scale, HADS) were assessed via self\u2010administered questionnaire. Clinical information (diagnosis, stage, and treatment information) was obtained from the cancer registry. Overall, 22% of participants reported oncological care modifications due to COVID\u201019, mostly in follow\u2010up care and rehabilitation. Modifications of active cancer treatment were reported by 5.8%. Among those, 50.5% had subclinical anxiety and 55.4% subclinical depression (vs. 37.4% and 45.4%, respectively, for unchanged active treatment). Age &lt;60\u2009years, female sex, lung cancer, low income, and contact restrictions to peer support groups or physicians were identified as independent risk factors for anxiety. Risk factors for depression were lung cancer (both sexes), leukemia\/lymphoma (females), recurrence or palliative treatment, living alone, low income, and contact restrictions to relatives, physicians, or caregivers. The study demonstrates that changes in active cancer treatment and contact restrictions are associated with impaired mental well\u2010being. The psychological consequences of treatment changes and the importance for cancer patients to maintain regular contact with their physicians should be considered in future responses to threats to public health.<\/jats:p>","DOI":"10.1002\/ijc.35204","type":"journal-article","created":{"date-parts":[[2024,10,3]],"date-time":"2024-10-03T10:24:11Z","timestamp":1727951051000},"page":"711-722","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Anxiety and depression in cancer patients and survivors in the context of restrictions in contact and oncological care during the\n                    <scp>COVID<\/scp>\n                    \u201019 pandemic"],"prefix":"10.1002","volume":"156","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7499-5376","authenticated-orcid":false,"given":"Daniela","family":"Doege","sequence":"first","affiliation":[{"name":"Unit of Cancer Survivorship, Division of Clinical Epidemiology and Aging Research German Cancer Research Center (DKFZ)  Heidelberg Germany"},{"name":"Epidemiological Cancer Registry of Baden\u2010W\u00fcrttemberg German Cancer Research Center (DKFZ)  Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julien","family":"Frick","sequence":"additional","affiliation":[{"name":"Unit of Cancer Survivorship, Division of Clinical Epidemiology and Aging Research German Cancer Research Center (DKFZ)  Heidelberg Germany"},{"name":"Medical Faculty of Heidelberg University of Heidelberg  Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel D.","family":"Eckford","sequence":"additional","affiliation":[{"name":"Division of Health Economics German Cancer Research Center (DKFZ)  Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lena","family":"Koch\u2010Gallenkamp","sequence":"additional","affiliation":[{"name":"Division of Clinical Epidemiology and Aging Research German Cancer Research Center (DKFZ)  Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Schlander","sequence":"additional","affiliation":[{"name":"Division of Health Economics German Cancer Research Center (DKFZ)  Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Baden\u2010W\u00fcrttemberg Cancer Registry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volker","family":"Arndt","sequence":"additional","affiliation":[{"name":"Unit of Cancer Survivorship, Division of Clinical Epidemiology and Aging Research German Cancer Research Center (DKFZ)  Heidelberg Germany"},{"name":"Epidemiological Cancer Registry of Baden\u2010W\u00fcrttemberg German Cancer Research Center (DKFZ)  Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,10,3]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(20)30201-1"},{"key":"e_1_2_11_3_1","unstructured":"Bundestag.Gesetz zum Ausgleich COVID\u201019 bedingter finanzieller Belastungen der Krankenh\u00e4user und weiterer Gesundheitseinrichtungen (COVID\u201019\u2010Krankenhausentlastungsgesetz). 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