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As awareness of KHE increases, it is imperative that the management of KHE be updated to reflect the latest evidence\u2010based guidelines. The aim of this study was to integrate the literature and Chinese expert opinions to provide updated recommendations that will guide the diagnosis, treatment, and prognosis of patients with KHE. According to this consensus statement, 28 nationally peer\u2010recognized experts in vascular anomalies and an expert in evidence\u2010based medicine were assembled and formed three consensus subgroups. A series of key themes and questions were developed for each group, including recommendations for diagnosis, treatment, and prognosis. A systematic search was conducted for English\u2010language articles published in PubMed and other relevant studies identified by the expert panel. A diagnosis of KHE necessitates the integration of clinical, imaging, and histologic features. The treatment of KHE should be tailored to the specific characteristics of each patient, including the size of the lesion, the presence of symptoms, the location, and the overall condition of the patient. In addition to focusing on the disease itself, it is also important to consider the complications of KHE and their impact on prognosis. The recommendations presented herein are intended to assist in the guidance of clinical practice and decision\u2010making in patients with KHE, with the objective of improving patient outcomes.<\/jats:p>","DOI":"10.1002\/ijc.35344","type":"journal-article","created":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T12:42:36Z","timestamp":1737376956000},"page":"1986-1994","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Consensus statement for the diagnosis, treatment, and prognosis of kaposiform hemangioendothelioma"],"prefix":"10.1002","volume":"156","author":[{"given":"Jiangyuan","family":"Zhou","sequence":"first","affiliation":[{"name":"Division of Oncology, Department of Pediatric Surgery, and Rare Diseases Center, West China Hospital Sichuan University  China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tong","family":"Qiu","sequence":"additional","affiliation":[{"name":"Division of 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