{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T20:09:14Z","timestamp":1793650154170,"version":"4.5.1"},"reference-count":46,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T00:00:00Z","timestamp":1748304000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T00:00:00Z","timestamp":1748304000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100013933","name":"CNIB Foundation","doi-asserted-by":"publisher","award":["INCa\u2010ResPP22\u2010002"],"award-info":[{"award-number":["INCa\u2010ResPP22\u2010002"]}],"id":[{"id":"10.13039\/100013933","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2025,9,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Cutaneous melanoma (CM) accounted for around 331,700 cancer cases globally in 2022. Ultraviolet radiation (UVR) is a major CM risk factor. In this study, we update and improve global estimates of UVR\u2010attributable CM cases. Population attributable fractions (PAFs) were calculated by age, sex, and country using GLOBOCAN 2022 national incidence estimates comparing to a minimally exposed Nordic 1930 birth cohort reference population. Adjustments for acral lentiginous melanoma were made to exclude non\u2010UVR\u2010associated melanomas. In sensitivity analyses, PAFs were recalculated with a theoretical minimally exposed 1903 South Thames, England birth cohort and world region\u2010specific reference populations. An estimated 267,353 (95% uncertainty intervals [UI]: 242,818, 278,638) CM cases were UVR attributable globally in 2022. Males contributed to a larger proportion (57%, 151,921 out of 267,353) of UVR\u2010attributable CMs. We found significant regional variation with the highest PAF observed in Australia\/ New Zealand, Northern Europe, and North America, all with more than 95% CM cases UVR\u2010attributable. Attributable age\u2010standardized rates were highest in regions with populations of lighter skin color such as Australia\/New Zealand, Northern Europe, and North America, with 75.68 (95%UI: 74.50, 76.86), 36.82 (95%UI: 36.38, 37.26) and 33.69 (95%UI: 33.47, 33.91) attributable cases per 100,000 people. By age group, the burden increased with age, with PAF of 76.39% (95%UI: 66.24, 81.01) among people aged 30\u201349 versus 86.13% (95%UI: 80.04, 88.99) among 70+ years. Most of the global CM burden in 2022 was UVR\u2010attributable. Primary prevention through increasing sun safety awareness and affordable sun protection provision options is key to reducing CM.<\/jats:p>","DOI":"10.1002\/ijc.35463","type":"journal-article","created":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T05:45:12Z","timestamp":1748324712000},"page":"1110-1119","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":53,"title":["Global burden of cutaneous melanoma incidence attributable to ultraviolet radiation in 2022"],"prefix":"10.1002","volume":"157","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-8862-133X","authenticated-orcid":false,"given":"Oliver","family":"Langselius","sequence":"first","affiliation":[{"name":"Cancer Surveillance Branch International Agency for Research on Cancer (IARC)  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1862-9371","authenticated-orcid":false,"given":"Harriet","family":"Rumgay","sequence":"additional","affiliation":[{"name":"Cancer Surveillance Branch International Agency for Research on Cancer (IARC)  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5560-2258","authenticated-orcid":false,"given":"Esther","family":"de Vries","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology and Biostatistics Pontificia Universidad Javeriana  Bogota Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2563-9559","authenticated-orcid":false,"given":"David C.","family":"Whiteman","sequence":"additional","affiliation":[{"name":"Population Health Department QIMR Berghofer Medical Research Institute  Brisbane Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0000-4111","authenticated-orcid":false,"given":"Ahmedin","family":"Jemal","sequence":"additional","affiliation":[{"name":"Surveillance and Health Equity Science American Cancer Society  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3229-1784","authenticated-orcid":false,"given":"D. Maxwell","family":"Parkin","sequence":"additional","affiliation":[{"name":"Nuffield Department of Medicine University of Oxford  Oxford UK"},{"name":"African Cancer Registry Network  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6017-741X","authenticated-orcid":false,"given":"Isabelle","family":"Soerjomataram","sequence":"additional","affiliation":[{"name":"Cancer Surveillance Branch International Agency for Research on Cancer (IARC)  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,27]]},"reference":[{"key":"e_1_2_12_2_1","volume-title":"Cancer","author":"Ferlay J","year":"2024"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2022.0160"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-148X.2011.00880.x"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.31527"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2011.486"},{"key":"e_1_2_12_7_1","volume-title":"International statistical Classification of Diseases and Related Health Problems, 10th revision","author":"World Health Organization","year":"2015"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.35278"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.3109\/02841861003782017"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2020.02.010"},{"key":"e_1_2_12_11_1","unstructured":"African Cancer Registry Network. 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