{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:53:22Z","timestamp":1773017602067,"version":"3.50.1"},"reference-count":43,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T00:00:00Z","timestamp":1762387200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T00:00:00Z","timestamp":1762387200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"publisher","award":["INV\u2010003617"],"award-info":[{"award-number":["INV\u2010003617"]}],"id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2026,4,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Cervical cancer is the most common cancer in Uganda. In 2015, a national human papillomavirus (HPV) vaccination program was initiated, targeting girls aged 10\u2009years. To provide a pre\u2010vaccination baseline to monitor HPV vaccine effectiveness, first\u2010void urine (FVU) samples were collected from females aged 16\u201321\u2009years in the General Population Cohort (GPC) in South\u2010East Uganda, between 2019 and 2023. HPV vaccination status was obtained from questionnaires and vaccination cards. FVU samples were tested for 28 HPV types using Allplex HPV28. Among 1009 participants, 28 type prevalence was 33%, and was higher among females reporting sexual intercourse (aPR\u2009=\u20093.7, 95%CI 2.8\u20134.8) and HIV infection (PR\u2009=\u20091.4, 95%CI 1.1\u20131.8). HPV16\/18 prevalence was 4.8% overall, and lower in 146 vaccinated (1.4%) than 783 unvaccinated (5.6%) females (aPR\u2009=\u20090.4, 95%CI 0.1\u20131.4). No decrease was observed in other high\u2010risk (aPR\u2009=\u20091.5, 95%CIs 1.0\u20132.2) or low\u2010risk (aPR\u2009=\u20091.4, 95%CIs 1.0\u20132.1) types which were more prevalent in vaccinated females. Among vaccinated 16\u201321\u2009year\u2010olds, 30.8% (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200945) received one, 44.5% (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200965) two, and 14.3% (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200921) three doses. Vaccination status was also obtained from 1121 younger girls aged 10\u201315\u2009years from the same GPC population, among whom 42.8% (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u2009480) were vaccinated, 47.1% (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u2009226) with one, 44.2% (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u2009212) two, and 6.7% (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200932) three doses. In conclusion, we report high HPV prevalence in young women in Uganda and see first impacts of vaccination on HPV16\/18 infection. This population, shown to have suboptimal HPV vaccine coverage and heterogeneity in doses received, can serve as a robust baseline for future evaluations of HPV vaccine effectiveness.\n                  <\/jats:p>","DOI":"10.1002\/ijc.70227","type":"journal-article","created":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T12:21:02Z","timestamp":1762431662000},"page":"2051-2059","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Human papillomavirus infection and vaccination among young females in rural Uganda"],"prefix":"10.1002","volume":"158","author":[{"given":"Rob","family":"Newton","sequence":"first","affiliation":[{"name":"MRC\/UVRI Uganda Research Unit  Entebbe Uganda"},{"name":"University of York  York UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanessa","family":"Tenet","sequence":"additional","affiliation":[{"name":"International Agency for Research on Cancer (IARC\/WHO), Early Detection, Prevention and Infections Branch  Lyon France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Mugisha","sequence":"additional","affiliation":[{"name":"MRC\/UVRI Uganda Research Unit  Entebbe Uganda"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beatrice","family":"Kimono","sequence":"additional","affiliation":[{"name":"MRC\/UVRI Uganda Research Unit  Entebbe Uganda"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alex","family":"Vorsters","sequence":"additional","affiliation":[{"name":"Centre for the Evaluation of Vaccination (CEV), Vaccine &amp; Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences University of Antwerp  Antwerp Flanders Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margo","family":"Bell","sequence":"additional","affiliation":[{"name":"Centre for the Evaluation of Vaccination (CEV), Vaccine &amp; Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences University of Antwerp  Antwerp Flanders Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7534-333X","authenticated-orcid":false,"given":"Gary M.","family":"Clifford","sequence":"additional","affiliation":[{"name":"International Agency for Research on Cancer (IARC\/WHO), Early Detection, Prevention and Infections Branch  Lyon France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,6]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21834"},{"key":"e_1_2_12_3_1","volume-title":"Global Cancer Observatory: Cancer Tomorrow (version 1.1)","author":"Ferlay J","year":"2024"},{"key":"e_1_2_12_4_1","unstructured":"World Health Organization.Global strategy to accelerate the elimination of cervical cancer as a public health problem.2020."},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(20)30860-4"},{"key":"e_1_2_12_6_1","unstructured":"The Republic of Uganda Ministry of Health.The National Cervical Cancer Prevention and Control Strategic Plan 2018\u20132023.2018."},{"key":"e_1_2_12_7_1","unstructured":"PATH.Uganda factsheet.2023."},{"key":"e_1_2_12_8_1","unstructured":"The Republic of Uganda.The Immunisation Act Kampala: Ministry of Health UNEPI.2017."},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)02178-4"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djab080"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1917338"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djad263"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dys234"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2701.191364"},{"key":"e_1_2_12_15_1","unstructured":"BaussanoI TenetV BagdasarovaK et al.HPV burden in armenia among unvaccinated women: A series of cross\u2010sectional population\u2010based prevalence surveys. 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