{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T04:41:29Z","timestamp":1791520889293,"version":"4.3.4"},"reference-count":48,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2026,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Population\u2010based cancer registry (PBCR) of Bhutan was established in Jigme Dorji Wangchuk National Referral Hospital (JDWNRH) in 2014 with the support of the Ministry of Health (Bhutan) and IARC Regional Hub, Tata Memorial Centre (TMC), Mumbai, India. This PBCR provides nationwide coverage (0.7 million population). We aim to present the cancer patterns in Bhutan for the years 2014\u20132022 using PBCR data. Trained registry staff collect cancer patient information by visiting various sources such as hospitals and diagnostic facilities. Data is entered into\n                    <jats:italic>CanReg5<\/jats:italic>\n                    software. Data quality and consistency are checked by the IARC Regional Hub\u2010TMC, Mumbai. The age\u2010specific rate and age\u2010adjusted rate were calculated using\n                    <jats:italic>CanReg5<\/jats:italic>\n                    software. In the 9\u2010year period (2014\u20132022), the PBCR registered 5906 incidence cancer cases, of which 2659 (45%) were males and 3247 (55%) were females. The age\u2010adjusted incidence rate for males and females was 88.3 and 113.2 per 100,000 population, respectively. Age\u2010adjusted mortality rates for males and females were 42.7 and 44.6 per 100,000 population, respectively. The leading cancer sites among males are stomach, esophagus, liver, lung, and rectum, and for females, cervix uteri, stomach, breast, lung, and thyroid. Cancer registry will play a pivotal role in boosting and monitoring screening program initiatives in Bhutan. Through effective linkages, it will build a robust database providing a cancer profile of the Bhutanese population which can be employed to devise effective cancer control activities in Bhutan.\n                  <\/jats:p>","DOI":"10.1002\/ijc.70308","type":"journal-article","created":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T04:46:57Z","timestamp":1770180417000},"page":"2829-2840","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Cancer pattern in Bhutan (2014\u20132022): Findings from population\u2010based cancer registry\u2014A pathway to monitor cancer control activities"],"prefix":"10.1002","volume":"158","author":[{"given":"Phub","family":"Tshering","sequence":"first","affiliation":[{"name":"Jigme Dorji Wangchuck National Referral Hospital (JDWNRH)  Thimphu Bhutan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ugyen","family":"Tshomo","sequence":"additional","affiliation":[{"name":"Jigme Dorji Wangchuck National Referral Hospital (JDWNRH)  Thimphu Bhutan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meera","family":"Chetri","sequence":"additional","affiliation":[{"name":"Jigme Dorji Wangchuck National Referral Hospital (JDWNRH)  Thimphu Bhutan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumitra","family":"Suberi","sequence":"additional","affiliation":[{"name":"Jigme Dorji Wangchuck National Referral Hospital (JDWNRH)  Thimphu Bhutan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yangdon","family":"Yangdon","sequence":"additional","affiliation":[{"name":"Department of Public Health Ministry of Health  Thimphu Bhutan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laigden","family":"Dzed","sequence":"additional","affiliation":[{"name":"Department of Public Health Ministry of Health  Thimphu Bhutan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tshewang","family":"Lhadon","sequence":"additional","affiliation":[{"name":"Department of Public Health Ministry of Health  Thimphu Bhutan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonali","family":"Bagal","sequence":"additional","affiliation":[{"name":"Centre for Cancer Epidemiology (CCE), Tata Memorial Centre  Mumbai Maharashtra India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharyu","family":"Mhamane","sequence":"additional","affiliation":[{"name":"Centre for Cancer Epidemiology (CCE), Tata Memorial Centre  Mumbai Maharashtra India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6723-802X","authenticated-orcid":false,"given":"Atul","family":"Budukh","sequence":"additional","affiliation":[{"name":"Centre for Cancer Epidemiology (CCE), Tata Memorial Centre  Mumbai Maharashtra India"},{"name":"Homi Bhabha National Institute (HBNI), Training School Complex  Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,2,3]]},"reference":[{"key":"e_1_2_13_2_1","unstructured":"Ministry of Health.Annual Health Bulletin. Policy and Planning Division (PPD) Ministry of Health (MoH) Royal Government of Bhuta.2022https:\/\/moh.gov.bt\/wp-content\/uploads\/2025\/01\/Annual-Health-Bulleti-2022_Link-3.pdf"},{"key":"e_1_2_13_3_1","unstructured":"FerlayJ ErvikM LamF et al.Global Cancer Observatory. International Agency for Research on Cancer Lyon France.2024https:\/\/gco.iarc.fr\/"},{"key":"e_1_2_13_4_1","unstructured":"JensenOM ParkinDM MacLennanR MuirCS SkeetRG.Cancer registration: principles and methods (IARC Scientific Publications No. 95). International Agency for Research on Cancer World Health Organization Lyon France.1991."},{"key":"e_1_2_13_5_1","unstructured":"The World Bank in Bhutan.2025.https:\/\/www.worldbank.org\/en\/country\/bhutan\/overview"},{"key":"e_1_2_13_6_1","unstructured":"Cancer Incidence and Mortality in Bhutan: 2014\u20132018.Report of the Population Based Cancer Registry Bhutan Jigme Dorji Wangchuck National Referral Hospital (JDWNRH) Thimphu Bhutan.2020."},{"key":"e_1_2_13_7_1","unstructured":"TshomoU TsheringP BagalS BudukhA.Cancer Incidence and Mortality in Bhutan: 2019\u20132022. National Cancer Control Program Department of Public Health Ministry of Health Thimphu Bhutan.2024https:\/\/moh.gov.bt\/wp-content\/uploads\/2025\/07\/A4_Final_PBCR-19-22-report.pdf"},{"key":"e_1_2_13_8_1","unstructured":"The Global Initiative for Cancer Registry Development.The Global Initiative for Cancer Registry Development.2024https:\/\/gicr.iarc.fr\/about-the-gicr\/"},{"key":"e_1_2_13_9_1","unstructured":"International Agency for Research on Cancer.CanReg5 Open Source Software (Lyon France: International Agency for Research on Cancer).2008http:\/\/www.iacr.com.fr\/index.php?option=com_content&view=article&id=9:canreg5&catid=68&Itemid=445"},{"key":"e_1_2_13_10_1","unstructured":"BudukhA DikshitR.IARC Regional Hub for Cancer Registration Mumbai \u2013 Journey over the Decade 2012\u20132022 Tata Memorial Centre (TMC) Mumbai India.2023."},{"key":"e_1_2_13_11_1","unstructured":"World Health Organization (WHO).International Classification of Diseases for Oncology 3rd edn (Geneva: WHO).2000https:\/\/www.who.int\/standards\/classifications\/other-classifications\/international-classification-of-diseases-for-oncology"},{"key":"e_1_2_13_12_1","unstructured":"Census Report \u2013 National Statistics Bureau Bhutan.2025https:\/\/www.nsb.gov.bt\/publications\/census-report\/"},{"key":"e_1_2_13_13_1","unstructured":"DhimalM DahalU KhadkaK et al.Cancer incidence and mortality in selected districts of Nepal in 2019. 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