{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T16:02:31Z","timestamp":1793721751654,"version":"4.6.1"},"reference-count":26,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T00:00:00Z","timestamp":1780790400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T00:00:00Z","timestamp":1780790400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2026,10,15]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Classic mid\u201020th\u2010century migrant studies demonstrated that gastric cancer risk declines after migration but does not fully converge to host\u2010country levels, implicating early\u2010life exposures and long disease latency. Whether these migration\u2010associated risk gradients remain detectable in contemporary low\u2010incidence settings has not been systematically evaluated using modern U.S. cancer surveillance data.<\/jats:p>\n                  <jats:p>We analyzed SEER and state cancer registry data linked to U.S. Census\u2013derived population denominators to estimate crude and age\u2010adjusted gastric cancer incidence from 2010 to 2022 in California and New York. Asian populations were disaggregated into Chinese, Japanese, Korean, and Vietnamese subgroups. Temporal trends were assessed using Joinpoint regression, and U.S. incidence patterns were contextualized against country\u2010of\u2010origin incidence. Scenario\u2010based extrapolations to 2035 were conducted.<\/jats:p>\n                  <jats:p>Gastric cancer incidence remained consistently higher among Asian populations than among non\u2010Hispanic Whites, with age\u2010adjusted incidence ranging from ~3.6\u20134.7 per 100,000 in non\u2010Hispanic Whites versus 12\u201326 per 100,000 in Korean populations. Disaggregated analyses showed persistent differences across subgroups, with Korean populations consistently exhibiting the highest incidence. Incidence declined significantly over time in California (annual percent change ~\u22121% to \u22123%) but not in New York. Extrapolations suggest that a clinically meaningful burden will persist among high\u2010risk subgroups through 2035.<\/jats:p>\n                  <jats:p>These findings demonstrate that migration\u2010associated variation in gastric cancer risk remains detectable and prevention\u2010relevant in contemporary U.S. populations, supporting migration\u2010informed approaches to risk stratification and prevention.<\/jats:p>","DOI":"10.1002\/ijc.70552","type":"journal-article","created":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T04:25:19Z","timestamp":1780892719000},"page":"1891-1903","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Migration\u2010Associated Variation in Gastric Cancer Risk in the United States: Implications for Risk Stratification"],"prefix":"10.1002","volume":"159","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7213-2761","authenticated-orcid":false,"given":"Chul S.","family":"Hyun","sequence":"first","affiliation":[{"name":"Section of Digestive Diseases Yale School of Medicine  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2169-4174","authenticated-orcid":false,"given":"Rong","family":"Wang","sequence":"additional","affiliation":[{"name":"Yale School of Public Health  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung Hwi","family":"Hong","sequence":"additional","affiliation":[{"name":"Severance Underwood Meta\u2010Research Center, Institute of Convergence Science Yonsei University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuehong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Yale School of Nursing  Orange Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2326-1820","authenticated-orcid":false,"given":"Jae Il","family":"Shin","sequence":"additional","affiliation":[{"name":"Section of Digestive Diseases Yale School of Medicine  New Haven Connecticut USA"},{"name":"Severance Underwood Meta\u2010Research Center, Institute of Convergence Science Yonsei University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,7]]},"reference":[{"key":"e_1_2_12_2_1","first-page":"43","article-title":"Studies of Japanese Migrants. I. Mortality From Cancer and Other Diseases Among Japanese in the United States","volume":"40","author":"Haenszel W.","year":"1968","journal-title":"Journal of the National Cancer Institute"},{"key":"e_1_2_12_3_1","first-page":"37","article-title":"Cancer Mortality Among the Foreign\u2010Born in the United States","volume":"26","author":"Haenszel W.","year":"1961","journal-title":"Journal of the National Cancer Institute"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008849014992"},{"key":"e_1_2_12_5_1","first-page":"1149","article-title":"Cancer Mortality Risk Among Japanese in the United States","volume":"65","author":"Locke F. B.","year":"1980","journal-title":"Journal of the National Cancer Institute"},{"key":"e_1_2_12_6_1","first-page":"1141","article-title":"Cancer Mortality Among Chinese in the United States","volume":"65","author":"King H.","year":"1980","journal-title":"Journal of the National Cancer Institute"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41575\u2010025\u201001098\u20100"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0959-8049(96)00062-7"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.3322\/canjclin.57.4.190"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1200\/OA\u201025\u201000063"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2022.101404"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"e_1_2_12_13_1","unstructured":"International Agency for Research on Cancer \u201cGlobal Cancer Observatory: Cancer Today \u201d(2020) https:\/\/gco.iarc.fr\/today."},{"key":"e_1_2_12_14_1","unstructured":"National Cancer Institute Division of Cancer Control and Population Sciences andSurveillance Research Program \u201cSurveillance Epidemiology and End Results (SEER) Program. SEER*Stat Database: Incidence\u2014SEER Research Plus Limited\u2010Field Data 21 Registries November 2024 Submission (2000\u20132022) Linked to County Attributes\u2014Total U.S. 1969\u20132023 Counties \u201d(April 2025) https:\/\/www.seer.cancer.gov."},{"key":"e_1_2_12_15_1","unstructured":"US Census Bureau \u201cAmerican Community Survey (ACS) Public Use Microdata Sample (PUMS) Technical Documentation \u201d(2024) https:\/\/www.census.gov\/programs\u2010surveys\/acs\/microdata.html."},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097\u20100258(20000215)19:3<335::AID\u2010SIM336>3.0.CO;2\u2010Z"},{"key":"e_1_2_12_17_1","unstructured":"National Cancer Institute \u201cJoinpoint Regression Program Version 5.4.0.0\u2014User Guide \u201d(2024) https:\/\/surveillance.cancer.gov\/joinpoint."},{"key":"e_1_2_12_18_1","first-page":"969","article-title":"Stomach Cancer Among Japanese in Hawaii","volume":"49","author":"Haenszel W.","year":"1972","journal-title":"Journal of the National Cancer Institute"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djt157"},{"key":"e_1_2_12_20_1","first-page":"3","article-title":"Cancer Situation in China: What Does the China Cancer Map Indicate From the First National Death Survey to the Latest Cancer Registration?","volume":"43","author":"Feng R.","year":"2023","journal-title":"Cancer Commun (Lond)"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/acprof:oso\/9780199778386.003.0013"},{"key":"e_1_2_12_22_1","first-page":"141","article-title":"Migration, Sociocultural Factors, and Local Cultural Worlds Among Fuzhounese Chinese Immigrants","volume":"6","author":"Lai G. Y. C.","year":"2012","journal-title":"International Journal of Culture and Mental Health"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(25)01635\u20106"},{"key":"e_1_2_12_24_1","first-page":"6735","article-title":"Human Gastric Carcinogenesis: A Multistep and Multifactorial Process","volume":"52","author":"Correa P.","year":"1992","journal-title":"Cancer Research"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.28999"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2020.07.049"}],"container-title":["International Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.70552","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ijc.70552","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.70552","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:09:12Z","timestamp":1787317752000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ijc.70552"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,7]]},"references-count":26,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,10,15]]}},"alternative-id":["10.1002\/ijc.70552"],"URL":"https:\/\/doi.org\/10.1002\/ijc.70552","archive":["Portico"],"relation":{},"ISSN":["0020-7136","1097-0215"],"issn-type":[{"value":"0020-7136","type":"print"},{"value":"1097-0215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,7]]},"assertion":[{"value":"2026-01-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-07","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}