{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T07:10:15Z","timestamp":1792566615691,"version":"4.5.0"},"reference-count":23,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T00:00:00Z","timestamp":1781481600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T00:00:00Z","timestamp":1781481600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2026,11,15]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Cancer stage at diagnosis is crucial to guide clinical decision making and support cancer surveillance, enabling meaningful international comparisons of epidemiological cancer indicators and evaluation of cancer control policies. The collection of stage information by population\u2010based cancer registries (PBCRs) is therefore essential, yet a comprehensive overview of stage availability across European PBCRs has been lacking. We analyzed the availability and completeness of stage at diagnosis reported by PBCRs affiliated with the European Network of Cancer Registries (ENCR) in the 2022 European Cancer Information System (ECIS) data call. The assessment focused on six major cancers, that is, breast, cervix, colorectum, gastric, lung, and prostate. Between 1990 and 2022, 67 (78%) PBCRs from 18 countries\u2014out of 86 registries submitting incidence data to ECIS by September 2025\u2014provided information on stage. Sixty\u2010five (97%) used the Tumor\u2010Nodes\u2010Metastasis (TNM) system, although four coded a substantial proportion of cases using other staging systems. Many countries showed improvements over time in reporting TNM stage. In the period 2017\u20132019, in most countries more than 80% of breast, cervical, colorectal, and lung cancer cases had TNM information, while gastric and prostate cancers exceeded 70%. Nevertheless, a few countries reported TNM stage for less than half of their cases. Overall, stage at diagnosis is available for a large proportion of cancer cases in Europe, demonstrating the commitment of PBCRs to high\u2010quality data collection. However, important gaps persist in some countries. Continued cooperation between the ENCR and ECIS is needed to support harmonized stage reporting across European registries.<\/jats:p>","DOI":"10.1002\/ijc.70593","type":"journal-article","created":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T06:16:30Z","timestamp":1781590590000},"page":"2540-2551","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Availability of Stage Information From Cancer Registries Providing Data to the European Cancer Information System for Six Selected Cancers"],"prefix":"10.1002","volume":"159","author":[{"given":"Cristina","family":"Bosetti","sequence":"first","affiliation":[{"name":"European Commission, Joint Research Centre (JRC)  Ispra Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Otto","family":"Visser","sequence":"additional","affiliation":[{"name":"Department of Registration Netherlands Comprehensive Cancer Organisation (IKNL)  Utrecht the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4788-968X","authenticated-orcid":false,"given":"Liesbet","family":"Van Eycken","sequence":"additional","affiliation":[{"name":"Belgian Cancer Registry  Brussels Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Pettersson","sequence":"additional","affiliation":[{"name":"European Commission, Joint Research Centre (JRC)  Ispra Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna Julia","family":"Bartnicka","sequence":"additional","affiliation":[{"name":"European Commission, Joint Research Centre (JRC)  Ispra Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadeusz","family":"Dyba","sequence":"additional","affiliation":[{"name":"Engineering Ingegneria Informatica S.p.A.  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgia","family":"Randi","sequence":"additional","affiliation":[{"name":"Piksel S.r.l  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuela","family":"Flego","sequence":"additional","affiliation":[{"name":"Piksel S.r.l  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raquel N.","family":"Carvalho","sequence":"additional","affiliation":[{"name":"European Commission, Joint Research Centre (JRC)  Ispra Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manola","family":"Bettio","sequence":"additional","affiliation":[{"name":"European Commission, Joint Research Centre (JRC)  Ispra Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"ECIS Working Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,15]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-019-0253-x"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.27651"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.33326"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2024.113557"},{"key":"e_1_2_11_6_1","unstructured":"European Commission \u201cEurope's Beating Cancer Plan (EBCP). Communication from the Commission to the European Parliament and the Council 2022\u201d https:\/\/health.ec.europa.eu\/system\/files\/2022\u201002\/eu_cancer\u2010plan_en_0.pd."},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2023.4837"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.2340\/1651-226X.2024.35232"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2017.07.015"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.3389\/frhs.2023.1039266"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.27957"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2016.177"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.33679"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.35516"},{"key":"e_1_2_11_15_1","unstructured":"IKNL \u201cStage at Diagnosis Distribution 2025\u201d https:\/\/nkr\u2010cijfers.iknl.nl\/viewer\/incidentie\u2010verdeling\u2010per\u2010stadium?language=en_GB&viewerId=d900cd39\u20109311\u20104c91\u20109140\u2010744078afe1a9."},{"key":"e_1_2_11_16_1","first-page":"48","article-title":"Measuring the Cancer Burden in Europe: The European Cancer Information System","volume":"7","author":"Bettio M.","year":"2019","journal-title":"European Medical Journal Oncology"},{"key":"e_1_2_11_17_1","unstructured":"European Commission Joint Research Centre \u201cData Protocol for European Cancer Information System (ECIS) 2025\u201d https:\/\/www.encr.eu\/call\u2010for\u2010data."},{"key":"e_1_2_11_18_1","unstructured":"European Commission \u201cCouncil Recommendation on Strengthening Prevention Through Early Detection: A New EU Approach on Cancer Screening Replacing Council Recommendation 2003\/878\/EC 2022\u201d https:\/\/health.ec.europa.eu\/system\/files\/2022\u201009\/com_2022\u2010474_act_en.pdf."},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.21237"},{"key":"e_1_2_11_20_1","volume-title":"Extent of Disease (EOD) 2018 General Coding Instructions","author":"Ruhl J.","year":"2023"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2009.02.012"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(09)70157-3"},{"key":"e_1_2_11_23_1","volume-title":"TNM Classification of Malignant Tumours","author":"Brierley J.","year":"2017"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2014.07.016"}],"container-title":["International Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.70593","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ijc.70593","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.70593","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T11:32:56Z","timestamp":1790076776000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ijc.70593"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,15]]},"references-count":23,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,11,15]]}},"alternative-id":["10.1002\/ijc.70593"],"URL":"https:\/\/doi.org\/10.1002\/ijc.70593","archive":["Portico"],"relation":{},"ISSN":["0020-7136","1097-0215"],"issn-type":[{"value":"0020-7136","type":"print"},{"value":"1097-0215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,15]]},"assertion":[{"value":"2026-02-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-01","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}