{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T12:03:29Z","timestamp":1791201809912,"version":"4.2.0"},"reference-count":42,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T00:00:00Z","timestamp":1783987200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T00:00:00Z","timestamp":1783987200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2026,12,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Socioeconomic position (SEP) influences cancer care and outcomes, even in countries with government\u2010funded healthcare. This population\u2010based study examined associations between SEP, rectal cancer care and survival of patients in the Netherlands. Data from 25,995 patients with Stage I\u2013III rectal cancer diagnosed between 2015 and 2023 were obtained from the Netherlands Cancer Registry. SEP was categorised as lower, intermediate or higher using income\u2010based postal code data. Associations between SEP and detection method, treatments, and outcomes were analysed using multivariable logistic regression. Relative survival and relative excess risk (RER) of death were calculated using a generalised linear model. Compared to lower SEP, higher SEP patients were younger (median age 66 vs. 71\u2009years), more often male (65% vs. 59%), had better performance status (71% vs. 52% PS0), fewer comorbidities (63% vs. 50% CCI 0) and lower obesity rates (15% vs. 23%). Higher rates of Stage I tumours (34% vs. 30%), screen\u2010detection (45% vs. 38%), laparoscopic surgery use (93% vs. 90%), and lower rates of colostomies (64% vs. 71%) and adverse in\u2010hospital outcomes (44% vs. 55%) were observed among higher SEP patients (all\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001). Five\u2010year relative survival improved with increasing SEP (79.5% lower, 82.4% intermediate, 84.9% higher SEP;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001), with lower excess mortality for higher SEP patients (RER 0.90, 95% CI 0.81\u20130.99). SEP\u2010related differences were observed in screening, stage at diagnosis, surgical treatment and survival. Although several disparities were partly explained by comorbidity and BMI, others persisted, highlighting the need for targeted strategies to reduce differences between SEP groups in rectal cancer management and outcomes.\n                  <\/jats:p>","DOI":"10.1002\/ijc.70627","type":"journal-article","created":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T04:28:46Z","timestamp":1784089726000},"page":"2665-2675","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association Between Socioeconomic Position and Diagnosis, Treatment and Survival of Patients With Stage I\u2013III Rectal Cancer in the Netherlands"],"prefix":"10.1002","volume":"159","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8788-1810","authenticated-orcid":false,"given":"Suzanne E. N.","family":"de Vries","sequence":"first","affiliation":[{"name":"Department of Surgery Netherlands Cancer Institute  Amsterdam the Netherlands"},{"name":"Department of Surgery Radboud University Medical Center  Nijmegen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0125-1429","authenticated-orcid":false,"given":"Felice N.","family":"van Erning","sequence":"additional","affiliation":[{"name":"Department of Research and Development Netherlands Comprehensive Cancer Organisation  Utrecht the Netherlands"},{"name":"Department of Surgery Catharina Hospital  Eindhoven the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mieke J.","family":"Aarts","sequence":"additional","affiliation":[{"name":"Department of Research and Development Netherlands Comprehensive Cancer Organisation  Utrecht the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice M.","family":"Couwenberg","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy Netherlands Cancer Institute  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laskarina J. K.","family":"Galanos","sequence":"additional","affiliation":[{"name":"Department of Research and Development Netherlands Comprehensive Cancer Organisation  Utrecht the Netherlands"},{"name":"Department of Surgery Catharina Hospital  Eindhoven the Netherlands"},{"name":"Grow \u2013 School for Oncology and Developmental Biology Maastricht University  Maastricht the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6775-7364","authenticated-orcid":false,"given":"Irene E. G.","family":"van Hellemond","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Catharina Hospital  Eindhoven the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ignace H. J. T.","family":"de Hingh","sequence":"additional","affiliation":[{"name":"Department of Research and Development Netherlands Comprehensive Cancer Organisation  Utrecht the Netherlands"},{"name":"Department of Surgery Catharina Hospital  Eindhoven the Netherlands"},{"name":"Grow \u2013 School for Oncology and Developmental Biology Maastricht University  Maastricht the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin","family":"Lurvink","sequence":"additional","affiliation":[{"name":"Department of Surgery Catharina Hospital  Eindhoven the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iris D.","family":"Nagtegaal","sequence":"additional","affiliation":[{"name":"Department of Pathology Radboud University Medical Center  Nijmegen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes H. W.","family":"de Wilt","sequence":"additional","affiliation":[{"name":"Department of Surgery Radboud University Medical Center  Nijmegen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marloes A. G.","family":"Elferink","sequence":"additional","affiliation":[{"name":"Department of Research and Development Netherlands Comprehensive Cancer Organisation  Utrecht the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,14]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-54444-2"},{"key":"e_1_2_11_3_1","unstructured":"\u201cNetherlands Cancer Registry \u201dwww.nkr\u2010cijfers.iknl.nl."},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000543921"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-023-16677-6"},{"issue":"2","key":"e_1_2_11_6_1","first-page":"89","article-title":"Epidemiology of Colorectal Cancer: Incidence, Mortality, Survival, and Risk Factors","volume":"14","author":"Rawla P.","year":"2019","journal-title":"Gastroenterology Review\/Przegl\u0105d Gastroenterologiczny"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.26677"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2022.08.018"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/0969141319887996"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2023.112942"},{"issue":"2","key":"e_1_2_11_11_1","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0264067","article-title":"Socioeconomic Differences in Participation and Diagnostic Yield Within the Dutch National Colorectal Cancer Screening Programme With Faecal Immunochemical Testing","volume":"17","author":"Meulen M. P.","year":"2022","journal-title":"PLoS One"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/1753-6405.12762"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2023.1081518"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6605949"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.33622"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2010.03.015"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/10732748231204474"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010025\u201017555\u20108"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2010.04.026"},{"key":"e_1_2_11_20_1","volume-title":"International Classification of Diseases for Oncology","author":"Fritz A.","year":"2000"},{"key":"e_1_2_11_21_1","volume-title":"TNM: Classification of Malignant Tumours","author":"Sobin L.","year":"2009"},{"key":"e_1_2_11_22_1","unstructured":"\u201cNetherlands S Data Per Postcode \u201dhttps:\/\/www.cbs.nl\/nl\u2010nl\/dossier\/nederland\u2010regionaal\/geografische\u2010data\/gegevens\u2010per\u2010postcode."},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000421-198212000-00014"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(87)90171-8"},{"key":"e_1_2_11_25_1","first-page":"101","article-title":"The Relative Survival Rate: A Statistical Methodology","volume":"6","author":"Ederer F.","year":"1961","journal-title":"National Cancer Institute Monograph"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2004.07.002"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.7018"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2025.1575820"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-24-1239"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6605962"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2015-009470"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)01154-X"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2024.e33318"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.9555"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sipas.2023.100167"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2021.03.050"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1080\/0284186X.2018.1557785"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2024.07.009"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000004702"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2012-001248"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.4251\/wjgo.v16.i6.2284"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-014-2735-4"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2026.116732"}],"container-title":["International Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.70627","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ijc.70627","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.70627","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T11:45:27Z","timestamp":1791200727000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ijc.70627"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,14]]},"references-count":42,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2026,12,1]]}},"alternative-id":["10.1002\/ijc.70627"],"URL":"https:\/\/doi.org\/10.1002\/ijc.70627","archive":["Portico"],"relation":{},"ISSN":["0020-7136","1097-0215"],"issn-type":[{"value":"0020-7136","type":"print"},{"value":"1097-0215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,14]]},"assertion":[{"value":"2025-12-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}