{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T09:42:19Z","timestamp":1792662139567,"version":"4.5.0"},"reference-count":56,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T00:00:00Z","timestamp":1784073600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T00:00:00Z","timestamp":1784073600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2026,12,15]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Primary screening for human papillomavirus (HPV) followed by treatment with thermal ablation (TA) is an important component of the global strategy to eliminate cervical cancer. However, evidence on post\u2010TA outcomes in women living with HIV (WLWH) remains limited. The aim of this study is to evaluate the risk and determinants of post\u2010TA CIN2+. As part of the AIMA\u2010CC study, WLWH from C\u00f4te d'Ivoire, Burkina Faso and Cambodia were screened using HPV testing (GeneXpert). All HPV\u2010positive women were biopsied and those with positive triage (positive visual inspection and\/or HPV\u2010161845) were treated with TA using a flat probe and followed for 12\u2009months with HPV testing and biopsies. Among the 456 WLWH (age: 30\u201359\u2009years) treated with TA and with valid histology, 396 (86%) attended the 12\u2010month follow\u2010up visit. HPV persistence (HPV of same GeneXpert channel at baseline and 12\u2010month post\u2010treatment) was 40% and was associated with baseline HPV16 positivity (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.007), age\u2009\u2265\u200940\u2009years (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.03) and CD4\u2009\u2264\u2009500 cells\/mm\n                    <jats:sup>3<\/jats:sup>\n                    (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.02). CIN2+ was detected at 12\u2009months in 12 (4%) of the 318 WLWH with valid histology and was associated with 12\u2010month HPV positivity (OR: 5.29 [1.46\u201328.46]). The risk of CIN2+ was particularly high among women with HPV\u201016 at 12\u2009months (OR: 15.53 [3.49\u201391.17]). HPV positivity at 12\u2009months had a sensitivity for detecting CIN2+ of 83% but a specificity of 54%. HPV\u201016 positivity had lower sensitivity (42%) but high specificity (&gt;\u200990%).\n                  <\/jats:p>\n                  <jats:p>In conclusion, there is an urgent need to improve TA management in WLWH who are at high risk of CIN2+ re\u2010occurrence post\u2010treatment.<\/jats:p>","DOI":"10.1002\/ijc.70648","type":"journal-article","created":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T04:12:16Z","timestamp":1784175136000},"page":"3016-3028","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Follow\u2010Up and Outcomes After Thermal Ablation Treatment Among\n                    <scp>HIV<\/scp>\n                    \u2010Infected Women From Resource\u2010Limited Countries With Positive\n                    <scp>HPV<\/scp>\n                    \u2010Based Screening: Results of the\n                    <scp>AIMA<\/scp>\n                    \u2010\n                    <scp>CC<\/scp>\n                    Cohort (\n                    <scp>ANRS<\/scp>\n                    12375)"],"prefix":"10.1002","volume":"159","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9037-6057","authenticated-orcid":false,"given":"Pierre","family":"Debeaudrap","sequence":"first","affiliation":[{"name":"Centre Population and Development (Ceped), French National Research Institute for Sustainable Development (IRD), Sorbonne Paris Nord University, Paris Cit\u00e9 University  France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Firmin Nongodo","family":"Kabore","sequence":"additional","affiliation":[{"name":"Muraz Centre, National Institute of Public Health  Bobo\u2010Dioulasso Burkina Faso"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Limsreng","family":"Setha","sequence":"additional","affiliation":[{"name":"Calmette Hospital  Phnom Penh 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