{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T12:18:05Z","timestamp":1788265085098,"version":"build-2803163510"},"reference-count":36,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T00:00:00Z","timestamp":1784678400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T00:00:00Z","timestamp":1784678400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["1K01HL175206"],"award-info":[{"award-number":["1K01HL175206"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl Journal of Cancer"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Venous thromboembolism (VTE) is a serious complication for breast cancer (BC) survivors. We identified records of female BC survivors from the Korean Health Insurance Service database between January 1, 2010, and December 31, 2016. After applying exclusion criteria (age\u2009&lt;\u200918\u2009years, prior cancers or VTE, absence of BC surgery, or missing data), 112,522\u2009BC survivors were included; for the comparison group, BC survivors were matched (1:3) to women without cancer history. VTE risk was evaluated with a Fine and Gray model, accounting for death as a competing risk; multiple time periods were analyzed. Associations between VTE risk and treatment modalities also were estimated. Over a mean analysis period of 7.4\u2009years, BC survivors had 3621 VTE events; their subdistribution hazard ratio (sHR) for VTE was greater than that of the comparison group (sHR 1.68, 95% CI 1.61\u20131.75). The risk was prominent within the first year post\u2010diagnosis (sHR 7.78, 95% CI 6.88\u20138.80) and attenuated in analyses restricted to VTE events occurring beyond 1\u2009year after diagnosis (sHR 1.34, 95% CI 1.28\u20131.40), but remained significantly elevated in landmark (delayed\u2010entry) analyses starting at later time points. Anthracycline (sHR 1.11, 95% CI 1.00\u20131.23) and taxane (sHR 1.73, 95% CI 1.57\u20131.91) therapies were associated with an increased risk of VTE in 1\u2010year landmark analysis. Female BC survivors are at increased risk of VTE, especially during the first year post\u2010diagnosis, which underscores the importance of VTE risk assessment for BC survivors.<\/jats:p>","DOI":"10.1002\/ijc.70662","type":"journal-article","created":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T06:46:37Z","timestamp":1784789197000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Mid\u2010 and Long\u2010Term Risk of Venous Thromboembolism Among Female Breast Cancer Survivors: A Nationwide Cohort Study"],"prefix":"10.1002","author":[{"given":"Jihun","family":"Kang","sequence":"first","affiliation":[{"name":"Department of Family Medicine Kosin University College of Medicine  Busan South Korea"},{"name":"Department of Family Medicine Saint Agnes Medical Center  Fresno California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wonyoung","family":"Jung","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine Perelman School of Medicine, University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bongseong","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Statistics and Actuarial Science Soongsil University  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyeonjin","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Digital Health Samsung Advanced Institute for Health Science and Technology, Sungkyunkwan University  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesang","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Kosin University College of Medicine  Busan South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael G.","family":"Fradley","sequence":"additional","affiliation":[{"name":"Cardio\u2010Oncology Program, Division of Cardiology, Department of Internal Medicine University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jawahar L.","family":"Mehta","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine University of Arkansas for Medical Sciences  Little Rock Arkansas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyungdo","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Statistics and Actuarial Science Soongsil University  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8128-8920","authenticated-orcid":false,"given":"Dong Wook","family":"Shin","sequence":"additional","affiliation":[{"name":"Supportive Care Center\/Department of Family Medicine Samsung Medical Center, Sungkyunkwan University School of Medicine  Seoul South Korea"},{"name":"Department of Clinical Research Design and Evaluation Samsung Advanced Institute for Health Science and Technology, Sungkyunkwan University  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5879-6879","authenticated-orcid":false,"given":"Yong\u2010Moon Mark","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Fay W. Boozman College of Public Health University of Arkansas for Medical Sciences  Little Rock Arkansas USA"},{"name":"Cancer Prevention and Population Sciences Research Program, Winthrop P. Rockefeller Cancer Institute University of Arkansas for Medical Sciences  Little Rock Arkansas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,22]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2000.18.17.3078"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.165.10.1173"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2006.07.4393"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.30364"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1160\/TH12-01-0010"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.164.15.1653"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2015-01-625582"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdq777"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1055\/a-1886-5991"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1160\/TH09-06-0397"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.19.01461"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annonc.2022.12.014"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11239-013-1015-8"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2014-005082"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1996.14.10.2731"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2021006209"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/cac2.12207"},{"key":"e_1_2_11_19_1","first-page":"799","article-title":"Data Resource Profile: The National Health Information Database of the National Health Insurance Service in South Korea","volume":"46","author":"Cheol Seong S.","year":"2017","journal-title":"International Journal of Epidemiology"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.23838\/pfm.2021.00135"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2018.33.e276"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.5009\/gnl210190"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.7570\/jomes23031"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1214\/aos\/1176350951"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/01621459.1999.10474144"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.110.957951"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2022.37"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-018-05086-8"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.24508"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-014-3140-2"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15123124"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000154545.84124.AC"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.2003.03976.x"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2018.10.002"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2024.0035"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2021006623"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djq211"}],"container-title":["International Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.70662","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ijc.70662","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.70662","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T11:44:32Z","timestamp":1788263072000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ijc.70662"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,22]]},"references-count":36,"alternative-id":["10.1002\/ijc.70662"],"URL":"https:\/\/doi.org\/10.1002\/ijc.70662","archive":["Portico"],"relation":{},"ISSN":["0020-7136","1097-0215"],"issn-type":[{"value":"0020-7136","type":"print"},{"value":"1097-0215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,22]]},"assertion":[{"value":"2025-11-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"ijc.70662"}}