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The role of social determinants of health (SDOH) in these aging trajectories remains understudied. We conducted a retrospective cohort study of 109,224 curatively treated Danish cancer survivors (lung, breast, prostate, or colon cancer, diagnosed between 1997 and 2018) and 574,022 age\u2010 and sex\u2010matched cancer\u2010free individuals. SDOH was assessed using educational level and cohabitation status. Using national registries, we investigated associations between SDOH and 16 post\u2010cancer new morbidities with Cox proportional hazard models and flexible parametric models. During a median 6.9\u2010year follow\u2010up, cancer survivors had significantly higher rates of new morbidities than cancer\u2010free individuals. Lung cancer survivors had elevated hazard rates for 14 morbidities, breast cancer survivors had increased rates for 12 morbidities, prostate cancer survivors exhibited elevated rates for 8 morbidities, and colon cancer survivors had rates for 14 morbidities. Educational disparities were evident: survivors with short education had higher rates for chronic respiratory disease (HRs: 1.30\u20131.55 across cancer types), heart failure (HRs: 1.50\u20131.54 in breast and colon), diabetes (HRs: 1.67\u20131.95 in breast, prostate, and colon), and depression (HRs: 1.32\u20131.37 in breast and colon). Living alone was also associated with increased but less pronounced rates. Cancer survivors experience elevated rates for age\u2010 and treatment\u2010related post\u2010cancer new morbidities compared to cancer\u2010free individuals. Sociodemographic disadvantages, particularly short education, further increase these rates. These findings suggest that SDOH play an important role in post\u2010cancer aging, highlighting the need for targeted interventions addressing social determinants in survivorship care.<\/jats:p>","DOI":"10.1002\/ijc.70770","type":"journal-article","created":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T16:23:16Z","timestamp":1791562996000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Persistent Health Disparities Among Adult Cancer Survivors"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1917-4241","authenticated-orcid":false,"given":"Trille K.","family":"Kjaer","sequence":"first","affiliation":[{"name":"Cancer Survivorship Danish Cancer Institute  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne K. 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Department of Oncology, Rigshospitalet University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanne K.","family":"Kjaer","sequence":"additional","affiliation":[{"name":"Unit of Virus, Lifestyle and Genes Danish Cancer Institute  Copenhagen Denmark"},{"name":"Department of Gynecology, Rigshospitalet University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ismail","family":"G\u00f6genur","sequence":"additional","affiliation":[{"name":"Department of Surgery, Center for Surgical Science Zealand University Hospital  K\u00f8ge Denmark"},{"name":"Institute for Clinical Medicine Copenhagen University  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lonneke","family":"van den Poll\u2010Franse","sequence":"additional","affiliation":[{"name":"Department of Psychosocial Research and Epidemiology The Netherlands Cancer Institute  Amsterdam the Netherlands"},{"name":"Center of Research on Psychology in Somatic Diseases, Department of Medical and Clinical Psychology Tilburg University  Tilburg the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5485-2730","authenticated-orcid":false,"given":"Susanne O.","family":"Dalton","sequence":"additional","affiliation":[{"name":"Cancer Survivorship Danish Cancer Institute  Copenhagen Denmark"},{"name":"Danish Research Center for Equality in Cancer (COMPAS), Department of Clinical Oncology &amp; Palliative Care Zealand University Hospital  Naestved Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,9]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2018.7192"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11764-024-01638-8"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2022.6881"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2007.10.9777"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djae211"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djz136"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-021-00580-3"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.3788"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/s43018-024-00745-w"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.17369"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.soc.012809.102529"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2021.101536"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurpub\/14.3.311"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-023-09683-2"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/curroncol29040211"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.6596"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlr.0000188986.84819.3a"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11764-022-01210-2"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2021.741334"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/s43587-021-00044-4"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyad189"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41416-025-03225-9"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.2147\/CLEP.S99470"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.2147\/CLEP.S99457"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.2147\/CLEP.S99484"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.2147\/CLEP.S99481"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.2147\/CLEP.S99458"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.2147\/CLEP.S100256"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1177\/1403494810393562"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1177\/1403494810387965"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1177\/1403494811399956"},{"key":"e_1_2_12_33_1","unstructured":"The Danish Health Authority \u201cSocial ulighed i sundhed og sygdom. 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