{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T02:28:16Z","timestamp":1773196096552,"version":"3.50.1"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,11,18]],"date-time":"2016-11-18T00:00:00Z","timestamp":1479427200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the usefulness of maternal serum c\u2010reactive protein (<jats:styled-content style=\"fixed-case\">CRP<\/jats:styled-content>), lipid peroxide, and oxygen radical absorbance capacity (<jats:styled-content style=\"fixed-case\">ORAC<\/jats:styled-content>), to predict the interval between membrane rupture and delivery in patients with preterm premature rupture of membranes (<jats:styled-content style=\"fixed-case\">PPROM<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The present prospective study included patients with singleton pregnancies experiencing <jats:styled-content style=\"fixed-case\">PPROM<\/jats:styled-content> at earlier than 34\u00a0weeks of pregnancy who underwent spontaneous vaginal delivery between August 1, 2010 and July 31, 2013 at Chonnam National University Hospital, Republic of Korea. Patients were categorized based on whether delivery occurred within 3\u00a0days of <jats:styled-content style=\"fixed-case\">PPROM<\/jats:styled-content> or after. <jats:styled-content style=\"fixed-case\">CRP<\/jats:styled-content> levels, lipid peroxide (using malondialdehyde levels), <jats:styled-content style=\"fixed-case\">ORAC<\/jats:styled-content>, protein carbonyl, and other potential risk factors were compared between the groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 72 patients included. Maternal serum <jats:styled-content style=\"fixed-case\">CRP<\/jats:styled-content> levels, malondialdehyde levels, and Bishop Score were higher in patients who underwent delivery within 3\u00a0days (all <jats:italic>P<\/jats:italic>&lt;0.05); <jats:styled-content style=\"fixed-case\">ORAC<\/jats:styled-content> levels were lower among these patients (<jats:italic>P<\/jats:italic>=0.002). A receiver operating characteristic curve analysis showed that <jats:styled-content style=\"fixed-case\">CRP<\/jats:styled-content>, malondialdehyde, and <jats:styled-content style=\"fixed-case\">ORAC<\/jats:styled-content> levels were predictive of delivery within 3\u00a0days after <jats:styled-content style=\"fixed-case\">PPROM<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Maternal serum <jats:styled-content style=\"fixed-case\">CRP<\/jats:styled-content>, malondialdehyde, and <jats:styled-content style=\"fixed-case\">ORAC<\/jats:styled-content> levels at admission were useful in predicting the latent period in patients with <jats:styled-content style=\"fixed-case\">PPROM<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.12024","type":"journal-article","created":{"date-parts":[[2017,1,13]],"date-time":"2017-01-13T04:43:47Z","timestamp":1484282627000},"page":"145-150","source":"Crossref","is-referenced-by-count":26,"title":["Maternal c\u2010reactive protein and oxidative stress markers as predictors of delivery latency in patients experiencing preterm premature rupture of membranes"],"prefix":"10.1002","volume":"136","author":[{"given":"Hyun Kyung","family":"Ryu","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Chonnam National University Medical School  Gwangju South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jong Ho","family":"Moon","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Chonnam National University Medical School  Gwangju South 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