{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T23:28:14Z","timestamp":1767137294000,"version":"build-2238731810"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,5,4]],"date-time":"2017-05-04T00:00:00Z","timestamp":1493856000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Gynecology & Obste"],"published-print":{"date-parts":[[2017,7]]},"abstract":"Abstract<\/jats:title>\n \n Objective<\/jats:title>\n To investigate the effect of endometrial injury on pregnancy outcomes among infertile women taking clomifene citrate.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n A prospective randomized trial was undertaken at an Egyptian hospital between January 26, 2015, and July 17, 2016. Eligible women (\u22651\u00a0year primary\/secondary\/unexplained infertility, aged 20\u201335\u00a0years, day\u20102 follicle\u2010stimulating hormone <12\u00a0\n IU<\/jats:styled-content>\n \/L, normal prolactin\/thyroid function\/uterine cavity, \u22651 patent tube, male partner with normal semen count and motility, 3 cycles of clomifene citrate without success) were randomly allocated (1:1) using computer\u2010generated numbers into intervention (received endometrial injury on cycle day 15\u201324) or control groups (sham procedure). Women began ovulation induction on days 3\u20135 of the following cycle. Participants and investigators were not masked to group assignment. The primary outcomes were clinical pregnancy, spontaneous abortion, and multiple pregnancy rates. Women who completed follow\u2010up were included in analyses.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The intervention group included 52 women and the control group 53 women. The clinical pregnancy rate was significantly higher in the intervention group (37% [n=19]) than in the control group (13% [n=7];\n P<\/jats:italic>\n =0.006). No differences between the intervention and control groups were noted for spontaneous abortion rate (11% [2\/19] vs 29% [2\/7];\n P<\/jats:italic>\n =0.287) or multiple pregnancy rate (11% [2\/19] vs 14% [1\/7];\n P<\/jats:italic>\n =0.790). No adverse effects were reported.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Endometrial injury before ovulation induction could improve chances of pregnancy and its outcomes.<\/jats:p>\n <\/jats:sec>\n \n ClinicalTrials.gov<\/jats:title>\n \n NCT<\/jats:styled-content>\n 02345837.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/ijgo.12178","type":"journal-article","created":{"date-parts":[[2017,4,11]],"date-time":"2017-04-11T08:26:01Z","timestamp":1491899161000},"page":"47-52","source":"Crossref","is-referenced-by-count":8,"title":["RETRACTED: A randomized trial of local endometrial injury during ovulation induction cycles"],"prefix":"10.1002","volume":"138","author":[{"given":"Medhat E.E.","family":"Helmy","sequence":"first","affiliation":[{"name":"Obstetrics and Gynecology Department Faculty of Medicine Menoufia University Shebin\u2010Elkom Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad 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Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,5,4]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dep343"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1447-0756.2005.00251.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2011.12.034"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1521-6934(02)00130-X"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/biolreprod\/7.1.82"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(03)00345-5"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-013-2785-0"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1447-0756.2012.02016.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmp048"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2008.01773.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.12539"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2006.05.062"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/GCO.0b013e32832a0654"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2010.02.022"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2007.05.064"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2008.01.043"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.3109\/09513590.2011.650750"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deu213"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo.143.6.8885"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2011.07.1055"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-009-1166-1"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2012.08.005"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.4103\/0974-1208.63116"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-828X.2009.01076.x"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-013-2931-8"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2012.06.012"}],"updated-by":[{"DOI":"10.1002\/ijgo.15566","type":"retraction","label":"Retraction","source":"retraction-watch","updated":{"date-parts":[[2024,5,4]],"date-time":"2024-05-04T00:00:00Z","timestamp":1714780800000},"record-id":"65707"},{"DOI":"10.1002\/ijgo.15566","type":"retraction","label":"Retraction","source":"publisher","updated":{"date-parts":[[2024,5,4]],"date-time":"2024-05-04T00:00:00Z","timestamp":1714780800000}}],"container-title":["International 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