{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T10:04:42Z","timestamp":1782295482292,"version":"3.54.5"},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,6,30]],"date-time":"2017-06-30T00:00:00Z","timestamp":1498780800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess first\u2010trimester ultrasound measurements for the prediction of early spontaneous abortion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In a prospective observational study in Jamshedpur, India, women with singleton pregnancies of 42\u201376\u00a0days were enrolled between November 2014 and April 2016. Inclusion criteria were spontaneous conception, embryonic cardiac activity, and regular menstrual cycle. Fetal crown\u2010to\u2010rump length (<jats:styled-content style=\"fixed-case\">CRL<\/jats:styled-content>), gestational sac diameter (<jats:styled-content style=\"fixed-case\">GSD<\/jats:styled-content>), yolk sac diameter (<jats:styled-content style=\"fixed-case\">YSD<\/jats:styled-content>), and fetal heart rate (<jats:styled-content style=\"fixed-case\">FHR<\/jats:styled-content>) were measured by transvaginal ultrasonography. Ultrasonography was repeated at 12\u00a0weeks and beyond to determine pregnancy continuation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 800 women, 140 (17.5%) experienced early spontaneous abortion. <jats:styled-content style=\"fixed-case\">CRL<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> GSD<\/jats:styled-content>, and <jats:styled-content style=\"fixed-case\">FHR<\/jats:styled-content> values below the 5th percentile (odds ratio [<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>] 26.48, 26.94, and 100.63, respectively), and <jats:styled-content style=\"fixed-case\">YSD<\/jats:styled-content> above the 95th percentile (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 1.04) were predictors of early abortion. Normal <jats:styled-content style=\"fixed-case\">YSD<\/jats:styled-content> did not reduce the risk of abortion if the other three parameters were below the 5th percentile (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 34.27). For every 10\u2010bpm decrease in <jats:styled-content style=\"fixed-case\">FHR<\/jats:styled-content> below 130, there was 26.7% increased risk of abortion. <jats:styled-content style=\"fixed-case\">GSD<\/jats:styled-content>\u2212<jats:styled-content style=\"fixed-case\">CRL<\/jats:styled-content> difference of less than 5\u00a0mm was associated with a higher likelihood of abortion (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 4.88).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>First\u2010trimester ultrasound measurements are predictors of early abortion. Risk assessment tables based on combinations of abnormal measures might improve prediction rates.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.12231","type":"journal-article","created":{"date-parts":[[2017,6,11]],"date-time":"2017-06-11T08:56:43Z","timestamp":1497171403000},"page":"325-330","source":"Crossref","is-referenced-by-count":29,"title":["Efficacy of first\u2010trimester ultrasound parameters for prediction of early spontaneous abortion"],"prefix":"10.1002","volume":"138","author":[{"given":"Mamta Rath","family":"Datta","sequence":"first","affiliation":[{"name":"Tata Main Hospital  Jamshedpur Jharkhand India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ankush","family":"Raut","sequence":"additional","affiliation":[{"name":"Tata Main Hospital  Jamshedpur Jharkhand India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,6,30]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(02)04694-0"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/epirev\/mxf006"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1975.tb00588.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.1993.12.11.665"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.humrep.a138544"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.humrep.a138510"},{"issue":"3","key":"e_1_2_7_8_1","first-page":"369","article-title":"Relationship of small\u2010for\u2010dates sac size to crown\u2010rump length and spontaneous abortion in patients with a known date of ovulation","volume":"78","author":"Nazari A","year":"1991","journal-title":"Obstet Gynecol"},{"key":"e_1_2_7_9_1","first-page":"459","article-title":"Predicting first\u2010trimester spontaneous abortion. 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