{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T06:49:35Z","timestamp":1791528575106,"version":"4.3.4"},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,8,18]],"date-time":"2017-08-18T00:00:00Z","timestamp":1503014400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2017,8,18]],"date-time":"2017-08-18T00:00:00Z","timestamp":1503014400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2017,11]]},"abstract":"Abstract<\/jats:title>\n \n Objective<\/jats:title>\n \n To determine whether deep\u2010infiltrating endometriosis (\n DE<\/jats:styled-content>\n ) carries an increased risk of appendiceal endometriosis (AppE) as compared with superficial endometriosis or no endometriosis.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n In a retrospective study, data were obtained by chart review of an internal database for women who underwent coincidental appendectomy during benign gynecologic surgery between July 2009 and February 2014 at a tertiary referral center in the\n USA<\/jats:styled-content>\n . Univariate, bivariate, and regression analyses were performed. The primary exposure was surgically documented endometriosis (\n DE<\/jats:styled-content>\n , superficial, or no endometriosis). The primary outcome was AppE.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Endometriosis was diagnosed for 151 (38.2%) of 395 women; 82 (54.3%) had\n DE<\/jats:styled-content>\n . The prevalence of AppE was 13.2% (52\/395) overall; 8 (11.6%) of 69 women with superficial endometriosis and 32 (39.0%) of 82 with\n DE<\/jats:styled-content>\n were affected. Frequency of AppE was increased among women with\n DE<\/jats:styled-content>\n , abnormal appendix appearance, and surgical indication (all\n P<<\/jats:italic>\n 0.001). Women with\n DE<\/jats:styled-content>\n had a 5.9\u2010fold (95% confidence interval [\n CI<\/jats:styled-content>\n ] 2.9\u201311.9) higher risk of AppE compared with women without endometriosis, controlling for appendiceal appearance and surgical indication, and a 2.7\u2010fold (95%\n CI<\/jats:styled-content>\n 1.2\u20136.2) higher risk of AppE compared with those with superficial endometriosis.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n Women with\n DE<\/jats:styled-content>\n have increased risk of AppE. Coincidental appendectomy should form part of complete endometriosis excision for these patients.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/ijgo.12286","type":"journal-article","created":{"date-parts":[[2017,7,29]],"date-time":"2017-07-29T11:06:44Z","timestamp":1501326404000},"page":"149-154","source":"Crossref","is-referenced-by-count":30,"title":["Risk of appendiceal endometriosis among women with deep\u2010infiltrating endometriosis"],"prefix":"10.1002","volume":"139","author":[{"given":"Janelle K.","family":"Moulder","sequence":"first","affiliation":[{"name":"Division of Minimally Invasive Gynecologic Surgery Department of Obstetrics and Gynecology University of North Carolina Chapel Hill NC USA"},{"name":"University of Tennessee Medical Center Knoxville TN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew T.","family":"Siedhoff","sequence":"additional","affiliation":[{"name":"Division of Minimally Invasive Gynecologic Surgery Department of Obstetrics and Gynecology Cedars\u2010Sinai Medical Center Los\u00a0Angeles CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn L.","family":"Melvin","sequence":"additional","affiliation":[{"name":"Yale School of Nursing New Haven CT USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth G.","family":"Jarvis","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology WakeMed Physician Practices Raleigh NC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kumari A.","family":"Hobbs","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology New York\u2010Presbyterian\/Lower Manhattan Hospital New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanne","family":"Garrett","sequence":"additional","affiliation":[{"name":"Division of Family Planning Department of Obstetrics and Gynecology University of North Carolina Chapel Hill NC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,8,18]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"93","article-title":"Metastatic or embolic endometriosis, due to the menstrual dissemination of endometrial tissue into the venous circulation","volume":"3","author":"Sampson JA","year":"1927","journal-title":"Am J Pathol"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)53570-5"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0412.2011.01097.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2005.01.015"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1159\/000317270"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-0997(1998)6:1<30::AID-IDOG7>3.0.CO;2-B"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2005.03.003"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2005.12.076"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-3804(05)80007-6"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.4293\/108680812X13517013317031"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-828X.2007.00811.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2010.08.042"},{"issue":"5","key":"e_1_2_7_14_1","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1097\/00006250-200511000-00060","article-title":"ACOG Committee Opinion #323: Elective coincidental appendectomy","volume":"106","author":"ACOG Committee on Gynecologic Practice","year":"2005","journal-title":"Obstet Gynecol"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwh090"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000142714.54857.f8"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmq050"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2012.05.031"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7292(02)00195-9"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181758ec6"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/del339"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2010.02.044"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2014.04.002"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(02)03331-9"}],"container-title":["International Journal of Gynecology & Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fijgo.12286","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijgo.12286","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ijgo.12286","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijgo.12286","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T05:58:20Z","timestamp":1791525500000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/ijgo.12286"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,18]]},"references-count":23,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["10.1002\/ijgo.12286"],"URL":"https:\/\/doi.org\/10.1002\/ijgo.12286","archive":["Portico"],"relation":{},"ISSN":["0020-7292","1879-3479"],"issn-type":[{"value":"0020-7292","type":"print"},{"value":"1879-3479","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,18]]}}}